SecReT6
SecReT6 ID928 experimental
StrainCampylobacter jejuni 108
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionJX436460
Location1..17012
CommentC. jejuni T6SS confers contact-dependent cytotoxicity towards red blood cells but not macrophages; Colonisation of mouse; adhesion to and invasion of cultured colonic epithelial cells
Functionanti-eukaryotic
T6SS TypeType i; subtype i1
experimental Experimental investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number011111111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1TagH1..900 [-], 900510027015TagH  Fha
2TssM897..4424 [-], 3528510027003TssM  TssM
3TssD4542..5057 [+], 516510027004TssD  TssD
4TssL5312..6085 [-], 774510027005TssL  TssL
5TssK6082..7479 [-], 1398510027006TssK  TssK
6TssJ7489..7935 [-], 447510027007TssJ  TssJ
7TssA8061..9308 [+], 1248510027008TssA  TssA
8TssB9377..9862 [+], 486510027009TssB  TssB
9TssC9864..11318 [+], 1455510027010TssC  TssC
10TssE11321..11713 [+], 393510027011TssE  TssE
11TssF11710..13431 [+], 1722510027012TssF  TssF
12TssG13428..14336 [+], 909510027013TssG  TssG
13TssI14486..17002 [+], 2517510027014TssI  TssI
 

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1TssD4542..5057 [+], 516510027004TssD Hcp

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Proteins        Genes
Homology immunity protein (immunity protein label, when available)
(1) Bleumink-Pluym NM et al. (2013). Identification of a Functional Type VI Secretion System in Campylobacter jejuni Conferring Capsule Polysaccharide Sensitive Cytotoxicity. PLoS Pathog. 9(5):e1003393. [PudMed:23737749] experimental
 
experimental This literature contains experimental investigation