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Organism: Nocardia sp. ATCC 202099
Accession No. of Nucleotide Sequence: GU564398
Location of the putative gene cluster: 25968..34683
    
Thiopeptide Series, Family: series e, nocathiacin
Thiopeptide: nocathiacin I  
Thiopeptide genotype: Type I

Table 1. The context of the putative gene cluster involved in the thiopeptide biosynthesis
Gene Position Strand Lenth(bp) Product Note Linkout
nocP10404..11303
-1
900pathway specific regulatory protein[NCBI] [UniProt]
nocS111505..12683
-1
1179glycosyltransferase[NCBI] [UniProt]
nocB12704..13912
-1
1209cytochrome P450 protein[NCBI] [UniProt]
nocQ13909..14532
-1
624methyltransferase[NCBI] [UniProt]
nocA14529..14984
-1
456hypothetical protein[NCBI] [UniProt]
nocS214990..15703
-1
714sugar N-dimethyltransferase[NCBI] [UniProt]
nocS315728..16972
-1
1245sugar 3-C-methyltransferase[NCBI] [UniProt]
nocS416984..17970
-1
987NDP-hexose 3-ketoreductase[NCBI] [UniProt]
nocS517988..19418
-1
1431NDP-hexose 2,3-dehydratase[NCBI] [UniProt]
nocS619424..20560
-1
1137sugar aminotransferase[NCBI] [UniProt]
nocT20591..21703
-1
1113cytochrome P450 protein[NCBI] [UniProt]
nocU21696..22934
-1
1239cytochrome P450 protein[NCBI] [UniProt]
nocR22956..23480
-1
525resistance protein; glyoxalase/bleomycin resistanceprotein /diox ygenase[NCBI] [UniProt]
nocV23507..24649
-1
1143cytochrome P450 protein[NCBI] [UniProt]
nocC24646..25926
-1
1281cytochrome P450 protein[NCBI] [UniProt]
nocD25968..26960
-1
993dehydratasenosD[NCBI] [UniProt]
nocE26965..29523
-1
2559dehydratasenosE[NCBI] [UniProt]
nocF29544..30983
-1
1440dehydrogenasenosF[NCBI] [UniProt]
nocG30980..32875
-1
1896cyclodehydratasenosG[NCBI] [UniProt]
nocH32902..34683
-1
1782hypothetical proteinnosH[NCBI] [UniProt]
nocI34680..35912
-1
1233ATP-dependent synthetase or ligase[NCBI] [UniProt]
nocK35933..36820
-1
888hydrolase/acyltransferase[NCBI] [UniProt]
nocL36848..37984
-1
1137radical SAM-dependent proteinType I thiopeptide-specific[NCBI] [UniProt]
nocM38432..38581
1
150NOC precursor peptideprecursor peptide[NCBI] [UniProt]
nocN38714..39976
1
1263radical SAM-dependent methyltransferase[NCBI] [UniProt]
nocO39973..40914
1
942hypothetical proteinnosO[NCBI] [UniProt]

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Table 2. Reference
Ding Y et al (2010). Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099. Mol Biosyst. 6(7):1180-5. [PudMed:20473441]