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Organism: Nonomuraea sp. Bp3714-39
Accession No. of Nucleotide Sequence: FJ461360
Location of the putative gene cluster: 4866..14255
    
Thiopeptide Series, Family: series d, thiomuracins
Thiopeptide: thiomuracin A  
Thiopeptide genotype: Type III

Table 1. The context of the putative gene cluster involved in the thiopeptide biosynthesis
Gene Position Strand Lenth(bp) Product Note Linkout
tpdI1..1212
-1
1212coproporphyrinogen III oxidase[NCBI] [UniProt]
tpdJ11209..2372
-1
1164cytochrome P450 monooxygenase[NCBI] [UniProt]
tpdJ22369..3589
-1
1221cytochrome P450 monooxygenase[NCBI] [UniProt]
tpdR3600..4331
-1
732TetR transcriptional regulator[NCBI] [UniProt]
tpdA4677..4826
1
150thiomuracin prepropeptideprecursor peptide[NCBI] [UniProt]
tpdB4866..7478
1
2613dehydratasenosE[NCBI] [UniProt]
tpdC7475..8290
1
816dehydratasenosD[NCBI] [UniProt]
tpdD8287..9246
1
960hypothetical proteinnosO[NCBI] [UniProt]
tpdE9243..10529
1
1287dehydrogenasenosF[NCBI] [UniProt]
tpdF10526..12418
1
1893hypothetical proteinnosH[NCBI] [UniProt]
tpdG12411..14255
1
1845cyclodehydratasenosG[NCBI] [UniProt]
tpdH14252..15586
1
1335peptidase[NCBI] [UniProt]

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Table 2. Reference
Morris RP et al (2009). Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu.. J Am Chem Soc.. 131(16):5946-55. [PudMed:19338336]