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Organism: Bacillus cereus ATCC 14579
Accession No. of Nucleotide Sequence: NC_004722
Location of the putative gene cluster: 4988049..4996167
    
Thiopeptide Series, Family: series d, thiocillin
Thiopeptide: thiocillin I  
Thiopeptide genotype: Type III

Table 1. The context of the putative gene cluster involved in the thiopeptide biosynthesis
Gene Position Strand Lenth(bp) Product Note Linkout
BC50724978496..4980043
-1
1548ABC transporter ATP-binding protein[NCBI] [UniProt] [KEGG]
BC50734980481..4980996
-1
516spermidine N1-acetyltransferase[NCBI] [UniProt] [KEGG]
BC50744981513..4981884
-1
372MerR family transcriptional regulator[NCBI] [UniProt] [KEGG]
BC50754982430..4982855
-1
42650S ribosomal protein L11[NCBI] [UniProt] [KEGG]
BC50764983112..4983894
-1
783Short chain dehydrogenase[NCBI] [UniProt] [KEGG]
BC50774983851..4984330
-1
480hypothetical protein[NCBI] [UniProt] [KEGG]
BC50784984409..4984834
-1
42650S ribosomal protein L11[NCBI] [UniProt] [KEGG]
BC50794984927..4985697
-1
771Short chain dehydrogenase[NCBI] [UniProt] [KEGG]
BC50804985716..4986513
-1
798methyltransferase[NCBI] [UniProt] [KEGG]
BC50814986506..4988074
-1
1569NADH oxidasenosF[NCBI] [UniProt] [KEGG]
BC50824988049..4989026
-1
978hypothetical proteinnosO[NCBI] [UniProt] [KEGG]
BC50834989031..4990002
-1
972lantibiotic biosynthesis proteinnosD[NCBI] [UniProt] [KEGG]
BC50844990018..4992633
-1
2616lanthionine biosynthesis proteinnosE[NCBI] [UniProt] [KEGG]
BC50854992661..4994304
-1
1644putative cytoplasmic proteinnosG[NCBI] [UniProt] [KEGG]
BC50864994656..4996167
-1
1512putative lantibiotic biosynthesis proteinnosH[NCBI] [UniProt] [KEGG]
BC50874996424..4996582
-1
159putative lantibiotic precursor peptideprecursor peptide[NCBI] [UniProt] [KEGG]
BC50884996628..4996786
-1
159putative lantibiotic precursor peptideprecursor peptide[NCBI] [UniProt] [KEGG]
BC50894996832..4996990
-1
159putative lantibiotic precursor peptideprecursor peptide[NCBI] [UniProt] [KEGG]
BC50904997036..4997194
-1
159putative lantibiotic precursor peptideprecursor peptide[NCBI] [UniProt] [KEGG]
BC50914997392..4998135
1
744SnoK-like protein[NCBI] [UniProt] [KEGG]
BC50924998132..4998464
1
333glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein[NCBI] [UniProt] [KEGG]
BC50934998622..4998933
1
312xanthine permease[NCBI] [UniProt] [KEGG]
BC50944999000..4999227
-1
228transposase[NCBI] [UniProt] [KEGG]

View genome context of this sequence in the genome browser
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Table 2. Reference
Wieland Brown LC et al (2009). Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin. Proc Natl Acad Sci U S A. 106(8):2549-53. [PudMed:19196969]
Liao R et al (2009). Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications.. Chem Biol. 16(2):141-7. [PudMed:19246004]