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GE37468
  
Thiopeptide:GE37468 (Series d)  ChemDraw eXchange file 
Genotype:Type III (No MIA (indolyl), no QA (quinolinic acid))
Structural Peptide:STNCFCYICCSCSSN
Antibiotics: Antibacterial;
Gram Nature: Gram+,Gram-;
Target Organism: Staphylococcus aureus Smith (MIC=0.016µg/ml);
Staphylococcus epidermidis ATCC 12228 (MIC=0.06µg/ml);
Staphylococcus haemolyticus L602 (MIC=0.13µg/ml);
Streptococcus pyogenes L49 (MIC=4µg/ml);
Streptococcus pneumoniae L44 (MIC=0.5µg/ml);
Enterococcus faecalis ATCC 7080 (MIC=0.016µg/ml);
Propionibacterium acnes ATCC 6919 (MIC=0.002µg/ml);
Clostridium perfringens L290 (MIC=0.004µg/ml);
Bacteroides fragilis ATCC 25285 (MIC=4µg/ml);
Haemophilus influenzae ATCC 19418(MIC>128µg/ml);
Escherichia coli L47(MIC>128µg/ml);
Pseudomonas aeruginosa ATCC 10145(MIC>128µg/ml);
Anticancer:[Patent: WO2002066046]
Producer Organism:Streptomyces sp. ATCC 55365/O/5;
Streptomyces sp. ATCC 55365;
Reference: Stella, et al. (1995). Antibiotic GE37468 A: a new inhibitor of bacterial protein synthesis. I. Isolation and characterization. J Antibiot (Tokyo). 48(8):780-6. [PudMed:7592021]  
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Analogues: 
(1) GE37468A     GE37468A JEPG file GE37468A ChemDraw eXchange file   gene cluster experimental 
CAS: 160262-65-7P
(2) GE37468B 
(3) GE37468C 

structure: Structure in JEPG file
ChemDraw eXchange file: ChemDraw eXchange file
PubChem Link: PubChem Link
gene cluster: Biosynthetic gene cluster identified
experimental: Data derived from experimental literature