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thiomuracins
  
Thiopeptide:thiomuracins (Series d)  ChemDraw eXchange file 
Genotype:Type III (No MIA (indolyl), no QA (quinolinic acid))
Structural Peptide:SCNCFCYICCSCSSA
Antibiotics: Antimicrobial;
Gram Nature: Gram+;
Target Organism: Staphylococcus aureus NCTC 8325-4 (MIC=0.125µg/ml);
Staphylococcus aureus tufA G826A(Gly275fSer) (MIC=4µg/ml);
Staphylococcus aureus rplK Δ 58-75(L11Δ P20-G25) (MIC=0.25µg/ml);
Producer Organism:Nonomuraea sp. Bp3714-39;
Reference: Morris, et al. (2009). Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu.. J Am Chem Soc.. 131(16):5946-55. [PudMed:19338336]  
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Analogues: 
(1) thiomuracin A     thiomuracin A JEPG file thiomuracin A ChemDraw eXchange file   gene cluster experimental 
CAS: 1146340-78-4
(2) thiomuracin B     thiomuracin B JEPG file thiomuracin B ChemDraw eXchange file  
CAS: 1035876-75-5
(3) thiomuracin C     thiomuracin C JEPG file thiomuracin C ChemDraw eXchange file  
CAS: 1035560-66-7
(4) thiomuracin D     thiomuracin D JEPG file thiomuracin D ChemDraw eXchange file  
CAS: 1035560-67-8
(5) thiomuracin E     thiomuracin E JEPG file thiomuracin E ChemDraw eXchange file  
CAS: 1035876-77-7
(6) thiomuracin F     thiomuracin F JEPG file thiomuracin F ChemDraw eXchange file  
CAS: 1035560-64-5
(7) thiomuracin G     thiomuracin G JEPG file thiomuracin G ChemDraw eXchange file  
CAS: 1035560-65-6
(8) thiomuracin H     thiomuracin H JEPG file thiomuracin H ChemDraw eXchange file  
CAS: 1035560-64-5 
(9) thiomuracin I     thiomuracin I JEPG file thiomuracin I ChemDraw eXchange file  
CAS: 1035560-68-9

structure: Structure in JEPG file
ChemDraw eXchange file: ChemDraw eXchange file
PubChem Link: PubChem Link
gene cluster: Biosynthetic gene cluster identified
experimental: Data derived from experimental literature