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TP-1161
  
Thiopeptide:TP-1161 (Series d)  ChemDraw eXchange file 
Genotype:Type III (No MIA (indolyl), no QA (quinolinic acid))
Structural Peptide:SCTTSGCACSSSSSS
Antibiotics: Antibacterial;
Gram Nature: Gram+;
Target Organism: Staphylococcus aureus 10 (MIC=1mcg/ml);
Staphylococcus aureus 3797 (MIC>32mcg/ml);
Staphylococcus aureus 3798(MIC>32mcg/ml);
Staphylococcus aureus 5 (MIC=0.5mcg/ml);
Staphylococcus aureus 100 (MIC=2.5mcg/ml);
Staphylococcus aureus ATCC 25923 (MIC=4mcg/ml);
Staphylococcus haemolyticus 161 (MIC=1mcg/ml);
Staphylococcus haemolyticus 1025 (MIC=0.5mcg/ml);
Staphylococcus haemolyticus 602 (MIC=1mcg/ml);
Staphylococcus haemolyticus 585 (MIC=0.5mcg/ml);
Staphylococcus epidermidis 533 (MIC=0.5mcg/ml);
Staphylococcus epidermidis 4603 (MIC=4mcg/ml);
Staphylococcus epidermidis 22 (MIC=0.5mcg/ml);
Staphylococcus epidermidis 9 (MIC=0.5mcg/ml);
Enterococcus faecalis 559 (MIC=1mcg/ml);
Enterococcus faecalis 568 (MIC=0.5mcg/ml);
Enterococcus faecalis 560 (MIC=1mcg/ml);
Enterococcus faecium 569 (MIC=1mcg/ml);
Enterococcus faecalis ATCC 29212 (MIC=0.25mcg/ml);
Streptococcus pneumoniae ATCC 49619 (MIC=0.5mcg/ml);
Streptococcus B 52 (MIC=0.5mcg/ml);
Streptococcus B 209 (MIC=0.5mcg/ml);
Producer Organism:Nocardiopsis sp. TFS65-07;
Reference: Engelhardt, et al. (2010). Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species. Appl Environ Microbiol. 76(15):4969-76. [PudMed:20562278]  
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Gene Cluster: gene cluster experimental 

structure: Structure in JEPG file
ChemDraw eXchange file: ChemDraw eXchange file
PubChem Link: PubChem Link
gene cluster: Biosynthetic gene cluster identified
experimental: Data derived from experimental literature