ThioFinder
Home 
Homologues of NosE
#OrganismProteinFunction
 1Streptomyces actuosus ATCC 25421NosEdehydratase
 2Nocardia sp. ATCC 202099NocEdehydratase
 3Streptomyces laurentii ATCC 31255TsrJdehydratase
 4Streptomyces sioyaensis ATCC 13989SioJdehydrotase
 5Nocardiopsis sp. TFS65-07TpaKputative dehydratase
 6Streptomyces hygroscopicus 10-22CltElantibiotic dehydratase domain protein
 7Nonomuraea sp. Bp3714-39TpdBdehydratase
 8Nonomuraea sp. WU8817TpdBdehydratase
 9Bacillus cereus ATCC 14579BC5084lanthionine biosynthesis protein
 10Propionibacterium acnes KPA171202PPA0859putative lanthionine biosynthesis protein
 11Catenulispora acidiphila DSM 44928Caci_4205Lantibiotic dehydratase domain-containing protein
 12Catenulispora acidiphila DSM 44928Caci_3692Lantibiotic dehydratase domain-containing protein
 13Salinispora tropica CNB-440Strop_2433lantibiotic dehydratase domain-containing protein
 14Salinispora arenicola CNS-205Sare_2588lantibiotic dehydratase domain-containing protein
 15Streptomyces griseus subsp. griseus NBRC 13350SGR_4412hypothetical protein
 16Thermobispora bispora DSM 43833Tbis_0550Lantibiotic dehydratase domain-containing protein
 17Sorangium cellulosum 'So ce 56'Sce9070hypothetical protein
 18Actinosynnema mirum DSM 43827Amir_3861Lantibiotic dehydratase domain protein
 19Verrucosispora maris AB-18-032VAB18032_21125Lantibiotic dehydratase domain-containing protein
 20Frankia sp. CcI3Francci3_4196hypothetical protein
 21Corynebacterium pseudotuberculosis FRC41Cpfrc_01626hypothetical protein
 22Lysinibacillus sphaericus C3-41Bsph_4017lanthionine biosynthesis protein
 23Herpetosiphon aurantiacus ATCC 23779Haur_0922lantibiotic dehydratase domain-containing protein
 24Clostridium cellulovorans 743BClocel_3634Lantibiotic dehydratase domain-containing protein
 25Streptomyces venezuelae ATCC 10712SVEN_5134hypothetical protein
 26Streptomyces bingchenggensis BCW-1SBI_02229Lantibiotic dehydratase domain protein
 27Propionibacterium acnes HL030PA1HMPREF9601_02024lantibiotic dehydratase
 28Micromonospora sp. ATCC 39149MCAG_03946hypothetical protein
 29Streptomyces sp. CSSNG_06377lantibiotic dehydratase domain-containing protein
 30Streptomyces griseus XylebKG-1SACT1_4711Lantibiotic dehydratase domain protein
 31Actinomyces viscosus C505HMPREF0059_01140basic proline-rich protein
 32Streptomyces sp. AA4SSMG_08017predicted protein
 33Streptomyces pristinaespiralis ATCC 25486SSDG_06099predicted protein
 34Bacillus cereus G9241BCE_G9241_0519lanthionine biosynthesis protein, putative
 35Bacillus sp. B14905BB14905_21638Lanthionine biosynthesis protein
 36Bacillus cereus NVH0597-99BC059799_0521lantibiotic dehydratase family protein
 37Lactobacillus gasseri JV-V03HMPREF0514_11731lantibiotic dehydratase, superfamily protein
 38Propionibacterium acnes SK187HMPREF1034_2448lantibiotic dehydratase, C-terminal domain protein
 39Actinomyces sp. oral taxon 170 str. F0386HMPREF9056_02781hypothetical protein
 40Corynebacterium pseudotuberculosis I19CpI19_1628Lantibiotic dehydratase, N terminus/C terminus family
 41Streptococcus pneumoniae INV104INV104_02840Lantibiotic biosynthesis protein
 42Streptomyces albus J1074SSHG_03898lantibiotic dehydratase domain-containing
 43Bacillus cereus BDRD-Cer4 Bcere0015_51750similar to Lanthionine biosynthesis protein of Bacillus cereus ATCC 14579 UniRef RepID=Q815Q1_BACCR
 44Actinomadura melliaura SCC 1655ORF4unknown
 45Streptomyces sp. NRRL 30471Mur1lantibiotic dehydratase domain-containing protein
 46Streptomyces laurentii ATCC 31255TsrCputative lantibiotic dehydratase
 47Bacillus atrophaeus 1942BATR1942_14075lantibiotic dehydratase domain-containing protein
 48Corynebacterium ulcerans 809CULC809_01698hypothetical protein
 49Corynebacterium ulcerans BR-AD22CULC22_01776hypothetical protein
 50Streptococcus downei F0415HMPREF9176_0871lantibiotic dehydratase, C-terminal domain protein
 51Lysinibacillus fusiformis ZC1BFZC1_19165hypothetical protein
 52Propionibacterium sp. 434-HC2HMPREF9948_1490lantibiotic dehydratase, C-terminal domain protein
 53Streptomyces sp. ATCC 55365GetDlantibiotic-type dehydratase
 54Corynebacterium pseudotuberculosis 3/99-5Cp3995_1663Lantibiotic dehydratase, N terminus/C terminus family
 55Corynebacterium diphtheriae INCA 402CDB402_1842lantibiotic dehydratase domain-containing protein
 56Corynebacterium diphtheriae CDCE 8392CDCE8392_1865lantibiotic dehydratase domain-containing protein
 57Corynebacterium diphtheriae HC03CDHC03_1857lantibiotic dehydratase domain-containing protein
 58Corynebacterium diphtheriae PW8CDPW8_1946lantibiotic dehydratase domain-containing protein
 59Corynebacterium diphtheriae 31ACD31A_1974lantibiotic dehydratase domain-containing protein
 60Corynebacterium diphtheriae BH8CDBH8_1949lantibiotic dehydratase domain-containing protein
 61Corynebacterium diphtheriae C7CDC7B_1945lantibiotic dehydratase domain-containing protein
 62Corynebacterium pseudotuberculosis 316Cp316_1662Lantibiotic dehydratase, N terminus/C terminus family
 63Corynebacterium pseudotuberculosis P54B96CpP54B96_1649Lantibiotic dehydratase, N terminus/C terminus family protein
 64Weissella paramesenteroides ATCC 33313HMPREF0877_1441possible lantibiotic epidermin biosynthesis protein EpiB
 65Streptomyces chartreusis NRRL 12338SchaN1_010100008060hypothetical protein
Protein:   NosE, dehydratase
Conserved Domains
 PF04738, Lant_dehyd_N, Lantibiotic dehydratase, N terminus
 PF04737, Lant_dehyd_C, Lantibiotic dehydratase, C terminus
Homology analysis using profile hidden Markov models
    Construct profile HMM(s): eleven sequences of NosE homologues experimentally reported, NosE.fasta
    link HMMER3 profile HMM file: NosE.hmm
    Generate HMM-logos with link LogoMat-M
NumberSequenceMultiple Alignment by link MUSCLE
 65Fasta  DNA   Protein
(1)Wieland Brown LC et al (2009). Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin. Proc Natl Acad Sci U S A. 106(8):2549-53. [PudMed:19196969]
(2)Kelly WL et al (2009). Thiostrepton biosynthesis: prototype for a new family of bacteriocins. J Am Chem Soc. 131(12):4327-34. [PudMed:19265401]
(3)Yu Y et al (2009). Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework. ACS Chem Biol. 4(10):855-64. [PudMed:19678698]
(4)Wang J et al (2010). Identification and analysis of the biosynthetic gene cluster encoding the thiopeptide antibiotic cyclothiazomycin in Streptomyces hygroscopicus 10-22. Appl Environ Microbiol. 76(7):2335-44. [PudMed:20154110]
(5)Ding Y et al (2010). Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099. Mol Biosyst. 6(7):1180-5. [PudMed:20473441]
(6)Engelhardt K et al (2010). Isolation and characterization of the gene cluster for biosynthesis of the thiopeptide antibiotic TP-1161.. Appl Environ Microbiol.. 76(21):7093-101.. [PudMed:20851988]
(7)Liao R et al (2009). Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications.. Chem Biol. 16(2):141-7. [PudMed:19246004]
(8)Liao R et al (2009). Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications.. Chem Biol. 16(2):141-7. [PudMed:19246004]
(9)Morris RP et al (2009). Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu.. J Am Chem Soc.. 131(16):5946-55. [PudMed:19338336]
(10)Morris RP et al (2009). Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu.. J Am Chem Soc.. 131(16):5946-55. [PudMed:19338336]
(11)Young TS et al (2011). Identification of the thiazolyl peptide GE37468 gene cluster from Streptomyces ATCC 55365 and heterologous expression in Streptomyces lividans. Proc Natl Acad Sci U S A. . [PudMed:21788474]