I. Information of ICE
ICEberg ID377
Name ICESa2603 This ICE is derived from experimental literature
ICEO ID ICEO_0000126
OrganismStreptococcus agalactiae 2603V/R
Size (bp)54349
GC content [Genome] (%)38.35[35.65]
Insertion site-
Species that ICE can be transferred to-
Nucleotide SequenceAE009948 (complete ICE sequence in this genome)
Replicon chromosome (2160267 bp, BioProject:330) [NC_004116]
Genome coordinates1256680..1311028 
Putative oriT region -
Putative relaxase -

II. ICE interaction with IME/CIME/

The interaction information of ICESa2603 is not available.

The graph information of ICESa2603 components from AE009948
Complete gene list of ICESa2603 from AE009948
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
1SAG12381252057..1252665 [-], 609hypothetical protein
2SAG12391252715..1252945 [-], 231conserved hypothetical protein
3SAG12411253409..1253684 [+], 276transposase OrfA, IS3 family
4SAG12431254003..1254293 [+], 291ISSdy1, transposase OrfA
5SAG12441254329..1255108 [+], 780ISSdy1, transposase OrfB
6SAG12451255213..1255329 [-], 117hypothetical protein
7SAG12461255316..1256485 [+], 1170hypothetical protein
8SAG12471256680..1257879 [-], 1200site-specific recombinase, phage integrase familyIntegrase 
9SAG12481257902..1258129 [-], 228conserved hypothetical protein
10SAG12491258408..1258632 [-], 225transcriptional regulator, Cro/CI family
11SAG12501258813..1260678 [-], 1866Tn5252, relaxase
12SAG12511260665..1261030 [-], 366Tn5252, Orf 9 protein
13SAG12521261037..1261399 [-], 363Tn5252, Orf 10 protein
14SAG12531261820..1263127 [-], 1308transposase, ISL3 family
15merA-11263287..1264927 [-], 1641mercuric reductase
16merR-11264956..1265348 [-], 393mercuric resistance operon regulatory protein MerR
17SAG12571266612..1268741 [-], 2130cation-transporting ATPase, E1-E2 family
18cadC1268734..1269102 [-], 369cadmium efflux system accessory protein
19SAG12591269305..1269604 [+], 300conserved hypothetical protein
20SAG12601269658..1270446 [-], 789hypothetical protein
21SAG12611270455..1271051 [+], 597conserved hypothetical protein
22SAG12621271225..1273312 [-], 2088cation-transporting ATPase, E1-E2 family
23SAG12641274268..1274714 [-], 447transcriptional repressor CopY, putative
24SAG12651275139..1275759 [-], 621cadmium resistance transporter, putative
25SAG12661276299..1276757 [+], 459hypothetical protein
26SAG12671276791..1277117 [+], 327hypothetical protein
27SAG12681277301..1277993 [+], 693repressor protein, putative
28SAG12691277996..1278130 [+], 135hypothetical protein
29SAG12701278136..1279551 [+], 1416ImpB/MucB/SamB family protein
30SAG12711279548..1279898 [+], 351conserved hypothetical protein
31SAG12721279885..1280193 [+], 309conserved hypothetical protein
32SAG12731280202..1280558 [-], 357conserved hypothetical protein
33SAG12741280548..1280937 [-], 390conserved hypothetical protein
34SAG12751280934..1281161 [-], 228hypothetical protein
35SAG12761281215..1282291 [-], 1077conserved hypothetical protein
36SAG12771282330..1282821 [-], 492hypothetical proteinPrgL, T4SS component 
37SAG12781283064..1283354 [-], 291hypothetical protein
38SAG12791283368..1283667 [-], 300conserved domain protein
39SAG12801283738..1290562 [-], 6825SNF2 family protein
40SAG12811290611..1291162 [-], 552hypothetical protein
41SAG12821291146..1291337 [-], 192calcium-binding protein, putative
42ssp-51291338..1296233 [-], 4896agglutinin receptorPrgB, T4SS component 
43abiGI1296512..1297102 [+], 591abortive infection protein AbiGI
44abiGII1297099..1297944 [+], 846abortive infection protein AbiGII
45SAG12861298030..1300831 [-], 2802Tn5252, Orf28PrgK, T4SS component 
46SAG12871300833..1303163 [-], 2331Tn5252, Orf26PrgJ, T4SS component 
47SAG12891303556..1304410 [-], 855Tn5252, Orf23
48SAG12901304429..1304671 [-], 243hypothetical protein
49SAG12921306506..1306994 [-], 489hypothetical protein
50SAG12931307071..1307655 [-], 585protease, putative
51SAG12941307658..1307891 [-], 234conserved hypothetical protein
52SAG12951307900..1308283 [-], 384conserved hypothetical protein
53SAG12961308294..1308722 [-], 429conserved hypothetical protein
54SAG12971308706..1310061 [-], 1356C-5 cytosine-specific DNA methylase
55SAG12981310113..1310208 [-], 96hypothetical protein
56SAG12991310210..1311028 [-], 819conserved hypothetical protein
57SAG13001311025..1311198 [-], 174conserved hypothetical protein
58rplL1311397..1311762 [-], 366ribosomal protein L7/L12
59rplJ1311826..1312326 [-], 501ribosomal protein L10
60SAG13031312759..1314867 [+], 2109ATP-dependent Clp protease, ATP-binding subunit
61SAG13041314851..1314949 [-], 99hypothetical protein
62SAG13051314960..1315904 [-], 945homocysteine S-methyltransferase MmuM, putative
flank Flanking regions

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
(1) Haenni M; Saras E; Bertin S; Leblond P; Madec JY; Payot S (2010). Diversity and mobility of integrative and conjugative elements in bovine isolates of Streptococcus agalactiae, S. dysgalactiae subsp. dysgalactiae, and S. uberis. Appl Environ Microbiol. 76(24):7957-65. [PudMed:20952646] experimental
(2) Davies MR; Shera J; Van Domselaar GH; Sriprakash KS; McMillan DJ (2009). A novel integrative conjugative element mediates genetic transfer from group G Streptococcus to other {beta}-hemolytic Streptococci. J Bacteriol. 191(7):2257-65. [PudMed:19168609] experimental
(3) Tettelin H; Masignani V; Cieslewicz MJ; Eisen JA; Peterson S; Wessels MR; Paulsen IT; Nelson KE; Margarit I; Read TD; Madoff LC; Wolf AM; Beanan MJ; Brinkac LM; Daugherty SC; DeBoy RT; Durkin AS; Kolonay JF; Madupu R; Lewis MR; Radune D; Fedorova NB; Scanlan D; Khouri H; Mulligan S; Carty HA; Cline RT; Van Aken SE; Gill J; Scarselli M; Mora M; Iacobini ET; Brettoni C; Galli G; Mariani M; Vegni F; Maione D; Rinaudo D; Rappuoli R; Telford JL; Kasper DL; Grandi G; Fraser CM (2002). Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae. Proc Natl Acad Sci U S A. 99(19):12391-6. [PudMed:12200547]
experimental experimental literature