CagL is a component of Cag T4SS. CagL is a specialized adhesin that is targeted to the pilus surface, where it binds to and activates integrin alpha5beta1 receptor on gastric epithelial cells through an arginine-glycine-aspartate motif. This interaction triggers CagA delivery into target cells as well as activation of focal adhesion kinase and Src. CagL is a VirB5 homologue

Proteins belonging to this kind of component are listed
(You can select < 50 proteins to perform sequence alignment by MUSCLE)
#ComponentProtein ID T4SS Accession Organism
1 CagL15645165CagNC_000915Helicobacter pylori 26695
2 CagL298736199CagNC_014256Helicobacter pylori B8
3 CagL208434459CagNC_011333Helicobacter pylori G27
4 CagL108562939CagNC_008086Helicobacter pylori HPAG1
5 CagL15611554CagNC_000921Helicobacter pylori J99
6 CagL210134741CagNC_011498Helicobacter pylori P12
7 CagL308182694CagNC_014555Helicobacter pylori PeCan4
8 CagL188527617CagNC_010698Helicobacter pylori Shi470
9 CagL308184300CagNC_014560Helicobacter pylori SJM180
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Multiple protein sequence alignment by MUSCLE online