T4SS ID447
StrainHelicobacter pylori P12
Repliconchromosome [Browse all T4SS(s) in this replicon]
Location13587..16496; 36339..40378
FunctionDNA uptake
ClassificationType IVA; Type P
experimental Experimental investigation has been performed on this T4SS.

T4SS components

The information of T4SS components from NC_011498
Region 1: 13587..16496
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1HPP12_0009 (groES)9151..9507 [-], 357210134210co-chaperonin GroES 
2HPP12_0010 (dnaG)9795..11474 [+], 1680210134211DNA primase 
3HPP12_001111471..12523 [+], 1053210134212argininosuccinate synthase 
4HPP12_001212615..13442 [+], 828210134213hypothetical protein 
5HPP12_0013 (comB2)13587..13868 [+], 282210134214ComB2 competence protein  ComB2
6HPP12_0014 (comB3)13868..14131 [+], 264210134215ComB3 competence protein  ComB3
7HPP12_0015 (comB4)14133..16496 [+], 2364210134216ComB4 competence protein  ComB4
8HPP12_001616729..18138 [+], 1410210134217hypothetical protein 
9HPP12_0017 (cheV-1)18238..19203 [+], 966210134218chemotaxis signal transduction protein CheV 
10HPP12_0018 (nspC)19200..20417 [+], 1218210134219carboxynorspermidine decarboxylase 
11HPP12_001920436..21011 [-], 576210134220lipid A 1-phosphatase 
Region 2: 36339..40378
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1HPP12_002731734..32147 [+], 414210134228hypothetical protein 
2HPP12_0028 (clpS)32183..32458 [+], 276210134229ATP-dependent clp protease adapter protein ClpS 
3HPP12_0029 (clpA)32458..34683 [+], 2226210134230ATP-dependent clp protease 
4HPP12_0030 (panD)34673..35023 [+], 351210134231aspartate alpha-decarboxylase 
5HPP12_003135034..35327 [+], 294210134232hypothetical protein 
6HPP12_003235327..36331 [+], 1005210134233hypothetical protein 
7HPP12_0033 (comB6)36339..37394 [+], 1056210134234ComB6 competence protein  ComB6
8HPP12_0034 (comb7)37410..37523 [+], 114210134235Comb7 competence protein  ComB7
9HPP12_0035 (comB8)37520..38263 [+], 744210134236ComB8 competence protein  ComB8
10HPP12_0036 (comB9)38263..39249 [+], 987210134237ComB9 competence protein  ComB9
11HPP12_0037 (comB10)39242..40378 [+], 1137210134238ComB10 competence protein  ComB10
12HPP12_003840448..41767 [+], 1320210134239bifunctional mannose-6-phosphate isomerase / mannose-1-phosphate guanylyltransferase 
13HPP12_0039 (gmd)41888..43033 [+], 1146210134240GDP-D-mannose dehydratase 
14HPP12_004043026..43958 [+], 933210134241GDP-fucose synthetase 
flank Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

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Proteins        Genes
(1) Karnholz A; Hoefler C; Odenbreit S; Fischer W; Hofreuter D; Haas R (2006). Functional and topological characterization of novel components of the comB DNA transformation competence system in Helicobacter pylori. J Bacteriol. 188(3):882-93. [PudMed:16428391] experimental in_silico
(2) Backert S; Kwok T; Konig W (2005). Conjugative plasmid DNA transfer in Helicobacter pylori mediated by chromosomally encoded relaxase and TraG-like proteins. Microbiology. 151(Pt 11):3493-503. [PudMed:16272373] experimental
(3) Hofreuter D; Odenbreit S; Haas R (2001). Natural transformation competence in Helicobacter pylori is mediated by the basic components of a type IV secretion system. Mol Microbiol. 41(2):379-91. [PudMed:11489125] experimental
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation