SecReT6: a web-based resource for type VI secretion systems found in bacteria

Overview of the classic T6SS assembly mode

Type VI secretion system (T6SS) is a class of sophisticated protein delivering apparatus, composed of 13 core components with or withnot accessory proteins in different species, involved in mediating antagonistic or synergistic communications between bacteria and/or bacteria and eukaryotes. This apparatus has been found to be widely distributed among Gram-negative bacterial species. To date, only a few datasets of T6SS core components are available, such as KEGG and MicrobeWiki, and two comprehensive databases EffectiveDB and BastionHub are mainly focus on effectors of several secretion systems in bacteria, lacking specific and integrated full-scale data of T6SS. Here, we have organized information derived from the reported literature of T6SS gene cluster, T6SS regulator and accessory protein, as well as cognate effector, immunity and structure protein, together with tools for T6SS classification and T6SS protein detection as the web-based resource SecReT6 (Type VI Secretion system Resource) 2.0 version. More...

Citation: J. Li, Y. Yao, H. H. Xu, L. Hao, Z. Deng, K. Rajakumar, H.Y. Ou* (2015) SecReT6: a web-based resource for type VI secretion systems found in bacteria. Environmental Microbiology, 2015 Jan 30. doi: 10.1111/1462-2920.12794. [Abstract]
Current version: 2.0 | Since: May 2012 | Recently update: July, 2020
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