SecReT6
T6SSs that participate in two functions

IDOrganism Replicon [Accession] Location TypeNote
945 experimental T6SS [BATJ01000011] Vpr kills competing bacteria mediated by T6SS1 and induces hemolysin‐independent morphological changes in macrophages.Vpr uses the T6SS1 MIX‐effector Vpr01570 to manipulate actin in macrophages.
941 experimental T6SS2 [KX118288] E. coli STEC004 cells deploy Rhs-CT1 to inhibit neighboring cells and protect themselves with the corresponding immunity protein CTI1.
948 experimental Aeromonas hydrophila NJ-35 chromosome [CP006870] 2935924..2976020i1 T6SS can secrete hcp and contributes to antiphagocytic activity against T.thermophila as well as the antibacterial property.
16 experimental Agrobacterium tumefaciens str. C58 chromosome linear [NC_003063] 1460756..1488734i5 anti-eukaryotic and anti-bacterial; effector translocation
942 E. coli (ETEC) strain PE027 T6SS [KX118287] i1 Wt-PE027 inhibited recipient cells by more than 100-fold compared with △CT3 and △T6SS2 (a ClpV2 mutant).
947 experimental Escherichia coli strain PE050 VgrG island T6SS [KX118292] i1 ETEC strains lacking vt1 or vgrG displayed a marked impairment in their capacity to kill Δvt1Δvti1 recipient cells, and VgrG and icmF are required for the antibacterial capacity of vt1+ strains.
946 experimental Escherichia coli strain PE117 T6SS [KX118293] i1 Δvt5Δvti5 mutant was significantly inhibited by vt5+ strains under cell contact-promoting conditions, and the complementation of vti5 in Δvt5Δvti5 provided effective protection against growth inhibition by vti1+ Wt-PE171 strains. VgrG and icmF are required for the antibacterial capacity of vt5+ strains.
944 experimental ETEC strain PE086 T6SS [KX118289] i1 The Hcp-ET1 is delivered by T6SS2 and t E.coli STEC004 cells deploy Hcp-ET1 to kill recipient cells.
3 experimental Pseudomonas aeruginosa PAO1 chromosome (H1-T6SS) [NC_002516] 83380..123495i3 anti-bacterial and anti-eukaryotic; effector translocation;virulence
4 experimental Pseudomonas aeruginosa PAO1 chromosome (H2-T6SS) [NC_002516] 1797958..1827821i1 anti-eukaryotic and anti-bacterial; effector translocation;virulence
5 experimental Pseudomonas aeruginosa PAO1 chromosome (H3-T6SS) [NC_002516] 2599893..2632231i4a anti-eukaryotic and anti-bacterial; effector translocation; virulence
152 experimental Pseudomonas aeruginosa UCBPP-PA14 chromosome [NC_008463] 3806993..3840213i1 anti-eukaryotic and anti-bacterial; virulence
150 experimental Pseudomonas aeruginosa UCBPP-PA14 chromosome [NC_008463] 82730..121410i3 anti-eukaryotic and anti-bacterial; effector translocation;virulence
42 experimental Pseudomonas syringae pv. tomato str. DC3000 chromosome [NC_004578] 6149242..6189243i1 anti-eukaryotic and anti-bacterial; effector translocation;virulence
790 experimental Vibrio cholerae V52 chromosome [NZ_AAKJ02000013] 12546..38192i1 anti-bacterial and anti-eukaryotic; effector translocation;virulence; adherence
43 experimental Vibrio parahaemolyticus RIMD 2210633 chromosome I [NC_004603] 1486402..1526996i1 anti-eukaryotic and anti-bacterial;effector translocation;adherence;virulence
949 experimental Vibrio parahaemolyticus strain 12-297/B C4271 T6SS [NZ_MYFG01000470] i1 V. parahaemolyticus 12-297/B T6SS1 is functional and can secret VgrG1b, as well as mediate antibacterial activity under warm marine-like conditions in the presence of surface-sensing activation.

experimental T6SS derived from experimental literature