Regulator List

All displayed regulators are experimentally validated.

Overview of the T6SS regulatory mechanism in Pseudomonas aeruginosa



Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Related T6SS Regulator type Regulatory pathway Organism                 Locus tag (Gene) Genome accession Coordinate (Strand) NCBI ID Target (Regulation)
REG0001 experimental T6SS0529 insolico; T6SS0530 insolico protein Transcription regulator Vibrio furnissii NCTC 11218 vfu_A02134 (ihfA) NC_016602 2226951..2227244 (-) 490864172 tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓)
REG0002 experimental T6SS0529 insolico; T6SS0530 insolico protein Transcription regulator Vibrio furnissii NCTC 11218 vfu_A02422 (ihfB) NC_016602 2516092..2516376 (-) 490864456 tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓)
REG0003 experimental T6SS1264 experimental protein TCS-HK Serratia marcescens RM66262 RT90_01105 (rcsC) JWLO01000001 232638..235499 (+) 735006326 RT90_01115 (rcsB) (↑)
REG0004 experimental T6SS1264 experimental protein TCS-RR Serratia marcescens RM66262 RT90_01115 (rcsB) JWLO01000001 235561..236211 (-) 735006328 vgrG promoter (↓)
REG0005 experimental T6SS1264 experimental protein TCS regulatory pathway Serratia marcescens RM66262 RT90_16255 (wecG) JWLO01000003 92056..92796 (+) 735005313 RT90_01105 (rcsC) (↑)
REG0006 experimental T6SS1033 experimental protein Tpp Serratia sp FS14 L085_RS13655 (ppka) NZ_CP005927 3028273..3029718 (-) 763151328 Unknown (↓)
REG0007 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK PA4740/Y880_04683 (pnp) NZ_CP020659 4637120..4639225 (-) 489185761 PA0527.1 (RsmY) (↑); PA3621.1 (RsmZ) (↑)
REG0008 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico ncRNA RsmA regulatory pathway Pseudomonas aeruginosa PAK PA0527.1 (RsmY) NZ_CP020659 586867..586990 (+) RsmA (Y880_06257) (↓)
REG0009 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico ncRNA RsmA regulatory pathway Pseudomonas aeruginosa PAK PA3621.1 (RsmZ) NZ_CP020659 4057543..4057658 (-) RsmA (Y880_06257) (↓)
REG0010 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK Y880_06257 (rsmA) NZ_CP020659 6213838..6214644 (-) 510932573 PA4492 mRNA (↑)
REG0011 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK Y880_05180 (rmsF) NZ_CP020659 5147809..5148024 (-) 489186811 tssA1 expression (↑)
REG0012 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein TCS-RR Pseudomonas aeruginosa PAK Y880_02189 (gacA/uvrY) NZ_CP020659 2199690..2200334 (-) 510933056 hcp expression (↓)
REG0013 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein TCS regulatory pathway Pseudomonas aeruginosa PAK Y880_03649 (suhB) NZ_CP020659 3616623..3617438 (+) 489183406 Y880_02189 (gacA/uvrY) (↓)
REG0014 experimental T6SS0929 experimental protein Tpp Serratia marcescens Db10 SMDB11_2275 (PpKA) HG326223 2399154..2400599 (+) 560174118 SMDB11_2267 (FHA) (↓)
REG0015 experimental T6SS0929 experimental protein Tpp Serratia marcescens Db10 SMDB11_2268 (PppA) HG326223 2390232..2391005 (+) 560174111 SMDB11_2267 (FHA) (↑)
REG0016 experimental T6SS0929 experimental protein Tpp Serratia marcescens Db10 SMDB11_2269 (RtkS) HG326223 2391034..2392020 (+) 560174112 SMDB11_2275 (PpKA) (↓)
REG0017 experimental T6SS0929 experimental protein Tpp Serratia marcescens Db10 SMDB11_2256 (TagF) HG326223 2380702..2381421 (+) 560174099 Unknown (↑)
REG0018 experimental T6SS0003 experimental; T6SS0004 experimental; T6SS0005 experimental protein Global regulator Pseudomonas aeruginosa PAO1 PA4462 (RpoN) NC_002516 4992870..4994363 (+) 15599658 PA1512 (hcpA) promotor (↓); PA5267 (hcpB) promotor (↓)
REG0019 experimental T6SS1001 insolico protein QS regulatory pathway Pectobacterium carotovorum subsp carotovorum PC1 PC1_3721 (Hfq) CP001657 4199890..4200189 (-) 251756660 hcp expression (↓)
REG0020 experimental T6SS1061 experimental ncRNA Unknown Vibrio cholerae 2740-80 Qrr4 NZ_CP016325 - () VCA0107 mRNA (↑)
REG0021 experimental T6SS1168 experimental protein Unknown Vibrio cholerae C6706 GPY04_RS11195 (CytR) NZ_CP046844 2449479..2450486 (-) 446146597 Unknown (↓)
REG0022 experimental T6SS1168 experimental protein QS regulatory pathway Vibrio cholerae C6706 GPY04_RS03590 (TfoX) NZ_CP046844 777344..777952 (+) 487807468 Unknown (↓)
REG0023 experimental T6SS1168 experimental protein QS regulatory pathway Vibrio cholerae C6706 GPY04_RS00870 (HapR) NZ_CP046844 164935..165546 (-) 446262243 Unknown (↓)
REG0024 experimental T6SS1168 experimental protein Global regulator Vibrio cholerae C6706 GPY04_RS13335/VC0070 (tsrA) NZ_CP046844 2888303..2888587 (+) 445982516 T6SS transcripts (↑)
REG0025 experimental T6SS1168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 Qrr1 quorum regulatory RNA NZ_CP046844/NZ_CP046845 - (-) VCA0107 mRNA (↑)
REG0026 experimental T6SS1168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 Qrr2 quorum regulatory RNA NZ_CP046844/NZ_CP046845 - (-) VCA0107 mRNA (↑)
REG0027 experimental T6SS1168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 Qrr3 quorum regulatory RNA NZ_CP046844/NZ_CP046845 - (-) VCA0107 mRNA (↑)
REG0028 experimental T6SS1168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 Qrr4 quorum regulatory RNA NZ_CP046844/NZ_CP046845 - (-) VCA0107 mRNA (↑)
REG0029 experimental T6SS1168 experimental protein QS regulatory pathway Vibrio cholerae C6706 GPY04_RS15835 (luxO) NZ_CP046844 273631..274983 (-) 446367907 VC0070 (tsrA) (↑)
REG0030 experimental T6SS1168 experimental protein Global regulator Vibrio cholerae C6706 GPY04_RS13825 (QstR) NZ_CP046844 2994333..2994977 (-) 447111060 Unknown (↓)
REG0031 experimental T6SS1168 experimental protein Global regulator Vibrio cholerae C6706 GPY04_RS15835 (luxO) NZ_CP046844 2994333..2994977 (-) 447111060 Unknown (↓)
REG0032 experimental T6SS1168 experimental protein QS regulatory pathway Vibrio cholerae C6706 GPY04_RS15835 (luxO) NZ_CP046845 273631..274983 (-) 446367907 GPY04_RS00870 (hapR) (↑)
REG0033 experimental T6SS1168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 GPY04_RS01040 (ChiS) NZ_CP046844 210606..213995 (-) 446410424 Necessory for TfoX/TfoR (↓)
REG0034 experimental T6SS1168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 GPY04_RS03200 (chiA2) NZ_CP046844 692014..695280 (+) 487807405 GPY04_RS01040 (ChiS) (↓)
REG0035 experimental T6SS1168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 GPY04_RS07700 (chiA1) NZ_CP046844 1709613..1712153 (-) 446755770 GPY04_RS01040 (ChiS) (↓)
REG0036 experimental T6SS1112 experimental protein Unknown Vibrio cholerae A1552 VC1920/VCA1552_01695 (LonA) NZ_CP024867 1845472..1847832 (-) 446970355 Unknown (↑)
REG0037 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein c-di-GMP regulatory pathway Pseudomonas aeruginosa PAK Y880_05519 (dgcP) NZ_CP020659 5487251..5489266 (-) 489205065 the levels of c-di-GMP (↓)
REG0038 experimental T6SS1041 insolico protein c-di-GMP regulatory pathway Pseudomonas savastanoi pv savastanoi NCPPB 3335 PSA3335_06200 (dgcP) NZ_CP008742 1344347..1346692 (+) 488618048 the levels of c-di-GMP (↓)
REG0039 experimental T6SS0002 experimental protein Global regulator Vibrio cholerae O1 biovar El Tor str. N16961 VC_RS13930 (VasH) NC_002506 128790..130382 (+) 446006938 VCA0017 (hcp-2) transcript (↓)
REG0040 experimental T6SS0003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 PA0592 (RsmA) NC_002516 650575..651381 (-) 15595789 FHA (PA0081) (↑)
REG0041 experimental T6SS0003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 PA5183a (RsmN) NC_002516 5836470..5836685 (-) 554753081 FHA (PA0081) (↑); PA3487 (pldA) expression (↑)
REG0042 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0075 (PppA) NC_002516 90106..90834 (-) 15595273 PA0081 (Fha-1/TagH) (↑)
REG0043 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0074 (PpkA) NC_002516 87000..90098 (-) 15595272 PA0081 (Fha-1/TagH) (↓)
REG0044 experimental T6SS0003 experimental TCS-RR Pseudomonas aeruginosa PAO1 PA2586 (gacA) NC_002516 2925788..2926432 (-) 15597782 hcp1 (PA0085) expression and secretion (↓)
REG0045 experimental T6SS0003 experimental TCS-HK Pseudomonas aeruginosa PAO1 PA0610 (prtN) NC_002516 672777..673091 (-) 15595807 PA0611 (prtR) (↑)
REG0046 experimental T6SS0003 experimental TCS-RR Pseudomonas aeruginosa PAO1 PA0611 (prtR) NC_002516 673191..673961 (-) 15595808 hcp1 (PA0085) expression and secretion (↑); PA2586 (gacA) (↑)
REG0047 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0072 (TagS) NC_002516 85085..86284 (-) 15595270 PA0073 (TagT) (↓)
REG0048 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0070 (TagQ) NC_002516 82404..83318 (-) 15595268 PA0071 (tagR) (↓)
REG0049 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0073 (TagT) NC_002516 86284..87003 (-) 15595271 PA0072 (TagS) (↓)
REG0050 experimental T6SS0003 experimental protein Unknown Pseudomonas aeruginosa PAO1 PA2492 (MexT) NC_002516 2807469..2808512 (+) 15597688 T6SS transcripts (↑)
REG0051 experimental T6SS0003 experimental protein Unknown Pseudomonas aeruginosa PAO1 PA1006 NC_002516 1090606..1090857 (+) 15596203 T6SS transcripts (↓)
REG0052 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0071 (tagR) NC_002516 83380..85092 (-) 15595269 PA0074 (PpkA) (↓)
REG0053 experimental T6SS0003 experimental protein Global regulator Pseudomonas aeruginosa PAO1 PA4856 (RetS) NC_002516 5452150..5454978 (+) 15600049 hcp1 (PA0085) expression and secretion (↑)
REG0054 experimental T6SS0003 experimental protein Global regulator Pseudomonas aeruginosa PAO1 PA3974 (LadS) NC_002516 4453289..4455676 (-) 15599169 hcp1 (PA0085) expression and secretion (↓)
REG0055 experimental T6SS0003 experimental Unknown Pseudomonas aeruginosa PAO1 PA4109 (AmpR) NC_002516 4592990..4593880 (-) 15599304 T6SS transcripts (↑)
REG0056 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0076 (TagF) NC_002516 90844..91524 (-) 15595274 hcp1 (PA0086) secretion (↑)
REG0057 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0081 (Fha-1/TagH) NC_002516 98263..99756 (-) 15595279 Unknown (↓); clpV (↓)
REG0058 experimental T6SS0003 experimental protein Unknown Pseudomonas aeruginosa PAO1 PA2976 (RNase E) NC_002516 3332881..3336054 (+) 15598172 PA0077 (icmF1) expression (↑)
REG0059 experimental T6SS0003 experimental; T6SS0004 experimental ncRNA QS regulatory pathway Pseudomonas aeruginosa PAO1 PA4704.1 (prrF1) NC_002516 5283960..5284110 (+) 4179187 T6SS transcripts (↓)
REG0060 experimental T6SS0003 experimental; T6SS0004 experimental ncRNA QS regulatory pathway Pseudomonas aeruginosa PAO1 PA4704.2 (prrF2) NC_002516 5284172..5284319 (+) 4179185 T6SS transcripts (↓)
REG0061 experimental T6SS0004 experimental protein Unknown Pseudomonas aeruginosa PAO1 PA0996 (pqsA) NC_002516 1078462..1080015 (+) 15596193 T6SS transcripts
REG0062 experimental T6SS0004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 PA1244 (QslA) NC_002516 1348060..1348401 (-) 15596441 H2-T6SS (PA1656) promotor (↑)
REG0063 experimental T6SS0004 experimental protein Transcription regulator Pseudomonas aeruginosa PAO1 PA4778 (CueR) NC_002516 5366257..5366655 (+) 15599972 tssA2 (-173 to -140 relative to the ATG start codon) (↓); hcp2 (-208 to -159 relative to the ATG start codon) (↓)
REG0064 experimental T6SS0004 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 PA4856 (RetS) NC_002516 5366257..5366655 (+) 15599972 H2-T6SS (↑)
REG0065 experimental T6SS0004 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 PA1430 (LasR) NC_002516 1558171..1558890 (+) 15596627 H2-T6SS promotor P (hsiA2) (↓)
REG0066 experimental T6SS0004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 PA3476 (rhlI) NC_002516 3889139..3889744 (-) 15598672 PA3477 (RhlR) (↓)
REG0067 experimental T6SS0004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 PA3477 (RhlR) NC_002516 3889925..3890650 (-) 15598673 T6SS transcript (↓)
REG0068 experimental T6SS0004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 PA4764 (Fur) NC_002516 5351675..5352079 (-) 15599958 H2-T6SS Transcription (↑)
REG0069 experimental T6SS0004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 PA4462 (rpoN) NC_002516 4992870..4994363 (+) 15599658 T6SS transcript (↑)
REG0070 experimental T6SS0004 experimental; T6SS0005 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 pa1663 (sfa2) NC_002516 1813395..1814906 (+) 15596860 PA4462 (rpoN) (↑); T6SS transcript (↑); T6SS transcript (↓)
REG0071 experimental T6SS0006 insolico protein Global regulator Escherichia coli O157:H7 str. EDL933 Z4049 (RpoS) NC_002655 3654380..3655372 (-) 446003635 Z1921 (KatN) (↓)
REG0072 experimental T6SS0006 insolico protein Global regulator Escherichia coli O157:H7 str. EDL933 Z5519 (OxyR) NC_002655 5033893..5034810 (+) 446948683 Z1921 (KatN) (↓)
REG0073 experimental T6SS0006 insolico protein Global regulator Escherichia coli O157:H7 str. EDL933 Z2013 (hns) NC_002655 1829490..1829903 (-) 447210122 Z0264 (hcp-2) (↑)
REG0074 experimental T6SS0014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 PP_4373 (FleQ) NC_002947 4963882..4965357 (-) 26991062 K1-T6SS (hcp1) expression (↑)
REG0075 experimental T6SS0014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 PP_0952 (RopN) NC_002947 1094567..1096060 (-) 26987688 PP_4373 (FleQ) (↑)
REG0076 experimental T6SS0014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 PP_0914 (BifA) NC_002947 1055990..1058071 (-) 26987650 the levels of c-di-GMP (↓)
REG0077 experimental T6SS0016 experimental protein Tpp Agrobacterium tumefaciens str. C58 Atu4335 (Fha/TagH) NC_003063 1467064..1468263 (-) 499280697 Unknown (↓)
REG0078 experimental T6SS0016 experimental protein Tpp Agrobacterium tumefaciens str. C58 Atu4330 (PpkA) NC_003063 1458366..1459271 (-) 737274050 Unknown (↓)
REG0079 experimental T6SS0016 experimental protein Tpp Agrobacterium tumefaciens str. C58 Atu4331 (TagF-PppA) NC_003063 1459258..1460673 (-) 159186120 Fha (Atu4335) (↑)
REG0080 experimental T6SS0016 experimental protein c-di-GMP regulatory pathway Agrobacterium tumefaciens str. C58 Atu2091 NC_003063 2054055..2054864 (-) 159185045 the levels of c-di-GMP (↑)
REG0081 experimental T6SS0016 experimental protein c-di-GMP regulatory pathway Agrobacterium tumefaciens str. C58 Atu5372 NC_003063 363152..364387 (+) 16119598 the levels of c-di-GMP (↑)
REG0082 experimental T6SS0016 experimental protein c-di-GMP regulatory pathway Agrobacterium tumefaciens str. C58 Atu1257 (DgcA) NC_003063 1244567..1245814 (-) 159184686 the levels of c-di-GMP (↑)
REG0083 experimental T6SS0016 experimental protein c-di-GMP regulatory pathway Agrobacterium tumefaciens str. C58 Atu2179 (DgcC) NC_003063 2154605..2155744 (-) 159185090 the levels of c-di-GMP (↑)
REG0084 experimental T6SS0016 experimental protein TCS-HK Agrobacterium tumefaciens str. C58 chvG NC_003062 34679..36469 (-) chvI (↓)
REG0085 experimental T6SS0016 experimental protein TCS-RR Agrobacterium tumefaciens str. C58 chvI NC_003062 36525..37250 (-) The intergenic region of the imp and hcp operons (↓)
REG0086 experimental T6SS0016 experimental protein TCS regulatory pathway Agrobacterium tumefaciens str. C58 exoR NC_003062 1702398..1703192 (-) chvG (↑)
REG0087 experimental T6SS0023 experimental protein Global regulator Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 STM1751 (H-NS) NC_003197 1847277..1847690 (+) 16765095 STM0272 (ClpV) promotor (↑); STM0279 (hcp) promotor (↑); STM0285 promotor (↑); STM0289 (VgrG) promotor (↑); STM0268 promotor (↑)
REG0088 experimental T6SS0023 experimental protein Global regulator Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 STM0693 (Fur) NC_003197 756397..756849 (-) 16764063 STM0272 (ClpV) promoter (↑)
REG0089 experimental T6SS0028 insolico protein Unknown Xanthomonas axonopodis pv. citri str. 306 xac4129 (ecfK/RpoE,ECF σ factor) NC_003919 4850278..4850805 (+) 489582896 Unknown (↓)
REG0090 experimental T6SS0028 insolico protein Unknown Xanthomonas axonopodis pv. citri str. 306 xac4127 (PknS) NC_003919 4846892..4849411 (+) 505284326 Unknown (↓)
REG0091 experimental T6SS0035 experimental protein TCS-RR Pseudomonas protegens Pf-5 PFL_RS17995 (gacA/uvrY/SirA) NC_004129 4110513..4111154 (-) 499374263 T6SS transcripts (↓)
REG0092 experimental T6SS0035 experimental protein Tpp Pseudomonas protegens Pf-5 PFL_RS30815 (pppA) NC_004129 6902924..6903658 (-) 499376669 Hcp secretion (↑)
REG0093 experimental T6SS0040 experimental protein QS regulatory pathway Pectobacterium atrosepticum SCRI1043 ECA_RS00520 (expI) NC_004547 125689..126339 (+) 499404281 T6SS transcripts (ECA4275[hcp1], ECA3428[hcp2] and ECA2866[hcp3]) (↓)
REG0094 experimental T6SS0040 experimental protein Global regulator Pectobacterium atrosepticum SCRI1043 ECA3435 (bEBP/VasH) NC_004547 3850745..3852298 (-) 499407476 T6SS gene cluster promoter (PECA3445) (↓); Hcp gene cluster promoter (PECA4275) (↓); Hcp gene cluster promoter (PECA2866) (↓)
REG0095 experimental T6SS0040 experimental protein Global regulator Pectobacterium atrosepticum SCRI1043 ECA0288 (rpoN) NC_004547 336007..337440 (-) 499404454 T6SS gene cluster promoter (PECA3445) (↓); Hcp gene cluster promoter (PECA4275) (↓); Hcp gene cluster promoter (PECA2866) (↓)
REG0096 experimental T6SS0041 insolico; T6SS0042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv. tomato str. DC3000 PSPTO_RS08845 (relA) NC_004578 1863879..1866122 (+) 494457621 T6SS transcripts (↓)
REG0097 experimental T6SS0041 insolico; T6SS0042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv. tomato str. DC3000 PSPTO_RS00410 (spoT) NC_004578 94805..96910 (-) 492171753 T6SS transcripts (↓)
REG0098 experimental T6SS0041 insolico; T6SS0042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv. tomato str. DC3000 PSPTO_RS04545 (fpRel) NC_004578 927082..927900 (+) 499415849 T6SS transcripts (↓)
REG0099 experimental T6SS0041 insolico; T6SS0042 experimental protein Global regulator Pseudomonas syringae pv. tomato str. DC3000 PSPTO_RS28060 (Sfa) NC_004578 6165047..6166564 (-) 499418021 T6SS transcripts (↓)
REG0100 experimental T6SS0043 experimental; T6SS0044 experimental protein TCS-HK Vibrio parahaemolyticus RIMD 2210633 VP_RS12495 (barA) NC_004603 2712492..2715290 (+) 491625032 Hcp expression and secretion (↓)
REG0101 experimental T6SS0043 experimental; T6SS0044 experimental protein TCS-RR Vibrio parahaemolyticus RIMD 2210633 VP_RS09470 (UvrY) NC_004603 2037468..2038112 (-) 491529158 CsrB (↓)
REG0102 experimental T6SS0043 experimental; T6SS0044 experimental protein carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP_RS12395 (CsrA) NC_004603 2688313..2688510 (-) 490550575 Hcp and vgrG expression and secretion (↓)
REG0103 experimental T6SS0043 experimental; T6SS0044 experimental ncRNA carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 CsrB1 NC_004603 243728..2439035 (+) VP_RS12395 (CsrA) (↑)
REG0104 experimental T6SS0043 experimental; T6SS0044 experimental ncRNA carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 CsrB2 NC_004603 3215766..3216162 (-) VP_RS12395 (CsrA) (↑)
REG0105 experimental T6SS0043 experimental; T6SS0044 experimental ncRNA carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 CsrB3 NC_004604 171473..171785 (+) VP_RS12395 (CsrA) (↑)
REG0106 experimental T6SS0043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 vp2049 (Thymidylate kinase,Tmk) NC_004603 2150113..2150745 (-) 28898823 T6SS1 (VgrG1) expression and secretion (↓)
REG0107 experimental T6SS0043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP1028 (TfoY) NC_004603 1077946..1078536 (-) 28897802 T6SS1 (VgrG1) expression and secretion (↓)
REG0108 experimental T6SS0043 experimental protein Global regulator Vibrio parahaemolyticus RIMD 2210633 vp1391 NC_004603 1491226..1492857 (-) 28898165 T6SS1 (VgrG1) expression and secretion (↓)
REG0109 experimental T6SS0043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 vp1407 NC_004603 1511565..1512017 (-) 28898181 T6SS1 (VgrG1) expression and secretion (↓)
REG0110 experimental T6SS0043 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP1133 (hns) NC_004603 1189718..1190125 (-) 28897907 VP1028 (TfoY) (↑)
REG0111 experimental T6SS0043 experimental; T6SS0044 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP2762 (AphA) NC_004603 2929909..2930448 (+) 28899536 T6SS1 transcript (↑); T6SS2 (VPA1027-1024, VPA1043-1028,VPA1044-1046) transcripts (↑)
REG0112 experimental T6SS0043 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP2516 (opaR) NC_004603 2653215..2653829 (+) 28899290 vp1407 (↑); VP1388 promotor (↑); VP1400 promotor (↑); VP1409 promotor (↑)
REG0113 experimental T6SS0044 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP2516 (opaR) NC_004605 2653215..2653829 (+) 28899290 T6SS2 (Hcp2) expression and secretion (↓); VPA1027-1024 transcript (↓); VPA1027-1024 transcript (↓); VPA1027-1024 transcript (↓); VPA1043-1028 transcript (↓); VPA1044-1046 transcript (↓)
REG0114 experimental T6SS0043 experimental protein Transcription regulator Vibrio parahaemolyticus RIMD 2210633 VP0820 (ToxR) NC_004603 847892..848770 (-) 28897594 VP1400 promotor (↑); VP1409 promotor (↑)
REG0115 experimental T6SS0044 experimental protein Transcription regulator Vibrio parahaemolyticus RIMD 2210633 VP0350 (CalR/LeuO) NC_004605 344763..345722 (+) 28897124 VPA1027 (hcp2) promotor (↓); VPA1043 (Fha) promotor (↓); VP1133 (H-NS) (↓)
REG0116 experimental T6SS0043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VPA1088 (cdpA) NC_004605 1147728..1150091 (+) 28900943 VP1028 (TfoY) (↑)
REG0117 experimental T6SS0043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VPA0739 (vdcA) NC_004605 772439..773809 (+) 28900594 VP1028 (TfoY) (↓)
REG0118 experimental T6SS0043 experimental protein Global regulator Vibrio parahaemolyticus RIMD 2210633 VP2516 (OpaR) NC_004603 2653215..2653829 (+) 28899290 T6SS1 (↓)
REG0119 experimental T6SS0044 experimental; T6SS0043 experimental protein QS regulatory pathway; c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP1241 (TfoX) NC_004603 1309223..1309810 (+) 28898016 T6SS2 (↓); T6SS1 (↓)
REG0120 experimental T6SS0049 insolico protein QS regulatory pathway Chromobacterium violaceum ATCC 12472 CV_RS20220 (CviR) NC_005085 4426186..4427046 (+) 1169634970 CV_RS06990 (VgrG) promotor (↓)
REG0121 experimental T6SS0049 insolico protein QS regulatory pathway Chromobacterium violaceum ATCC 12472 CV_RS23145 (CviI) NC_005085 4426967..4427620 (-) 499450174 CV_RS20220 (CviR) (↓)
REG0122 experimental T6SS0084 experimental protein QS regulatory pathway Vibrio fischeri ES114 VF2177 (LitR) NC_006840 2446537..2447142 (+) 59712784 Unknown (↓)
REG0123 experimental T6SS0084 experimental protein Global regulator Vibrio fischeri ES114 VF0896 (TfoX) NC_006840 986000..986629 (+) 59711503 T6SS transcripts (↓)
REG0124 experimental T6SS1277 experimental protein Global regulator Aliivibrio fischeri strain FQ-A001 VFFQA001_02105 (rpoN) NZ_SJSX01000002 62995..64464 (-) 501526930 hcp1/hcp transcript (↓)
REG0125 experimental T6SS1278 experimental protein Global regulator Aliivibrio fischeri strain FQ-A001 VFFQA001_15620 (VasH) NZ_SJSX01000004 359608..360108 (+) 1027725198 Unknown (↓)
REG0126 experimental T6SS0070 experimental protein Transcription regulator Burkholderia mallei ATCC 23344 BMAA1517 NC_006349 1646532..1647593 (-) 499517952 Hcp1 (BMAA0742) expression (↓)
REG0127 experimental T6SS0070 experimental protein TCS-RR Burkholderia mallei ATCC 23344 BMAA0746 (VirG) NC_006349 764773..765510 (+) 490311617 Hcp1 (BMAA0742) expression (↓)
REG0128 experimental T6SS0070 experimental protein TCS-HK Burkholderia mallei ATCC 23344 BMAA0745 (VirA) NC_006349 762932..764776 (+) 490305845 Hcp1 (BMAA0742) expression (↓)
REG0129 experimental T6SS0070 experimental protein TCS-RR Burkholderia mallei ATCC 23344 BMAA0746 (VirG) NC_006349 764773..765510 (+) 53717366 BMAA0742 (Hcp1) expression (↓); BMAA0729.1 (TssM1) expression (↓)
REG0130 experimental T6SS0070 experimental protein TCS-HK Burkholderia mallei ATCC 23344 BMAA0745 (VirA) NC_006349 763148..764776 (+) 53717365 BMAA0746 (VirG) (↓)
REG0131 experimental T6SS0074 insolico protein Unknown Burkholderia pseudomallei K96243 BPSL3431 (TctR) NC_006350 4073388..4074029 (-) 53721038 T6SS-2 (hcp2) transcript (↑)
REG0132 experimental T6SS0076 insolico; T6SS0077 insolico protein Unknown Burkholderia pseudomallei K96243 BPSL2246 (PpiB) NC_006350 2708622..2709113 (+) 53719855 T6SS-3 (BPSS2099/TssCIII and BPSS2098/HcpIII) expression (↑); T6SS-6 (hcp6) transcript (↓)
REG0133 experimental T6SS0077 insolico protein Unknown Burkholderia pseudomallei K96243 BPSS1504 NC_006351 2052905..2055547 (+) 499518990 hcp1 secretion
REG0134 experimental T6SS0077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 BPSS1546 (BsaN) NC_006351 2100565..2101230 (-) 490660320 BPSS1495 (virA) promotor (↓)
REG0135 experimental T6SS0077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 BPS_RS27070 (bicA) NC_006351 2087441..2087956 (-) 490293043 BPSS 1495(virA) (↓)
REG0136 experimental T6SS0077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 BPS_RS27175 (bprP) NC_006351 2105881..2106081 (+) 490293055 BPSS1546 (BsaN) (↓)
REG0137 experimental T6SS0077 insolico protein TCS-RR; BsaN regulon Burkholderia pseudomallei K96243 BPSS1495 (virA) NC_006351 2038711..2040555 (-) 499518988 T6SS-1 transpript (↓)
REG0138 experimental T6SS0077 insolico protein TCS-HK; BsaN regulon Burkholderia pseudomallei K96243 BPSS1494 (virG) NC_006351 2037977..2038714 (-) 490663798 BPSS1495 (virA) (↓)
REG0139 experimental T6SS0077 insolico protein bspR-dependent signalling cascade Burkholderia pseudomallei K96243 BPSL1105 (bprP) NC_006350 1275668..1276300 (+) 490290369 tssA expression (↓)
REG0140 experimental - protein bspR-dependent signalling cascade bprp HM447214 175..1146 (+) 298239796 tssA expression (↓)
REG0141 experimental - protein bspR-dependent signalling cascade bsaN - - () tssA expression (↓)
REG0142 experimental - protein bspR-dependent signalling cascade bspR HM358865 258..890 (+) 298239780 tssA expression (↓)
REG0143 experimental - protein bspR-dependent signalling cascade bprc - - () tssA expression (↓)
REG0144 experimental T6SS0077 insolico protein bspR-dependent signalling cascade Burkholderia pseudomallei K96243 BPSS1520 (bprC) NC_006351 2072125..2073186 (-) 499518995 tssA expression (↓)
REG0145 experimental T6SS0077 insolico protein TCS-HK Burkholderia pseudomallei K96243 BPSS1495 (virA) NC_006351 2038711..2040555 (-) 53722517 hcp1 expression (↓)
REG0146 experimental T6SS0077 insolico protein TCS-RR Burkholderia pseudomallei K96243 BPSS1494 (virG) NC_006351 2037977..2038714 (-) 53722516 hcp1 expression (↓)
REG0147 experimental T6SS0081 experimental protein TCS-RR Francisella tularensis subsp. tularensis SCHU S4 FTT1557c/FNU0663.2 (pmrA) NC_006570 1618742..1619428 (-) 489108239 T6SS transcription (↓)
REG0148 experimental T6SS0086 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv. syringae B728a PSYR_RS19090 (relA) NC_007005 4380642..4382885 (-) 499587809 T6SS transcripts (↓)
REG0149 experimental T6SS0086 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv. syringae B728a PSYR_RS01070 (spoT) NC_007005 223004..225109 (-) 489499092 T6SS transcripts (↓)
REG0150 experimental T6SS0086 experimental protein TCS-HK Pseudomonas syringae pv. syringae B728a Psyr_3698 (gacS) NC_007005 4385550..4388303 (+) 499587812 T6SS transcription (↓)
REG0151 experimental T6SS0086 experimental protein QS regulatory pathway Pseudomonas syringae pv. syringae B728a Psyr_4339 (ladS) NC_007005 5191591..5193585 (-) 639463044 T6SS transcription (↓)
REG0152 experimental T6SS0086 experimental protein QS regulatory pathway Pseudomonas syringae pv. syringae B728a Psyr_4408 (retS) NC_007005 5270882..5273671 (+) 489494774 T6SS transcription (↑)
REG0153 experimental T6SS0113 experimental protein Global regulator Burkholderia thailandensis E264 BTH_I1281 (OxyR) NC_007651 1432632..1433591 (+) 497575020 BTH_RS09735 (T6SS-4) Promotor,−536 to −186 relative to the ATG start codon (↑)
REG0154 experimental T6SS0113 experimental protein Global regulator Burkholderia thailandensis E264 bth_I0691 (Zur) NC_007651 796074..796538 (-) 497578547 BTH_RS09735 (T6SS-4) Promotor,−541 to −1 relative to the ATG start codon (↑)
REG0155 experimental T6SS0115 experimental protein QS regulatory pathway Burkholderia thailandensis E264 BTH_II1510 (BtaR1) NC_007650 1779070..1779789 (-) 497583165 BTH_I2691/BTH_I2693-99/BTH_I2701-702 (↓)
REG0156 experimental T6SS0125 insolico protein other regulator Pseudomonas entomophila L48 pvfC NC_008027 - () T6SS secreted proteome (↓)
REG0157 experimental T6SS0150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 rmsF NZ_JARI00000000 - (-) tssA1 RNA (↑); RsmY/Z (↑)
REG0158 experimental T6SS0150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_52570 (RsmA) NC_008463 4660393..4660578 (-) 489176459 RSMF (↑); tssA1 RNA (↑); RSMA (↑)
REG0159 experimental T6SS0150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_RS20260/PA1120 (YfiN/TpbB) NC_008463 4435431..4436738 (-) 489207392 Hcp1 production (↓)
REG0160 experimental T6SS0150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_RS15060 (PA2133 phosphodiesterase) NC_008463 3294000..3294857 (-) 489200657 Hcp1 production (↑)
REG0161 experimental T6SS0150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_RS06615 (WspR) NC_008463 1413158..1414201 (+) 489183089 Hcp1 production (↓)
REG0162 experimental T6SS0150 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 RsmY NC_008463 596840..596963 (+) Unknown
REG0163 experimental T6SS0150 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 RsmZ NC_008463 1500352..1500467 (+) Unknown
REG0164 experimental T6SS0150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_RS05020 (LadS) NC_008463 1069280..1071716 (+) 15599169 Unknown
REG0165 experimental T6SS0150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_64230/PA4856 (RetS) NC_008463 5722815..5725643 (+) 489202068 Unknown
REG0166 experimental T6SS0152 experimental; T6SS0151 experimental; T6SS0150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_45960 (lasR) NC_008463 4085339..4086058 (-) 489173455 TssA2 (PA14_43050) promotor (↓); HSI-III transcripts (↓); HSI-I transcripts (↑)
REG0167 experimental T6SS0152 experimental; T6SS0151 experimental; T6SS0150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_51340 (MvfR) NC_008463 4562837..4563835 (+) 489176730 Upstream of pqs operon (↓); HSI-III transcripts (↓); HSI-I transcripts (↑)
REG0168 experimental T6SS0150 experimental; T6SS0152 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_51380 (pqsE) NC_008463 4566077..4566982 (+) 489176725 T6SS Transciption (↓)
REG0169 experimental T6SS0150 experimental; T6SS0152 experimental; T6SS0151 experimental protein Global regulator Pseudomonas aeruginosa UCBPP-PA14 PA14_22470 (PA3225) NC_008463 1955624..1956553 (-) 489182081 PA14_00990 (TssA) promotor (↓); TssA1 (PA14_00990) transcript (↑); TssA2 (PA14_43050) transcript (↑); TssB3 (PA14_34070) transcript (↑)
REG0170 experimental T6SS0150 experimental; T6SS0152 experimental; T6SS0151 experimental protein Global regulator Pseudomonas aeruginosa UCBPP-PA14 PA14_20290 (AmrZ) NC_008463 1747602..1747928 (-) 489182353 TssA1 (PA14_00990) promotor (↓); TssA2 (PA14_43050) promotor (↑); TssB3 (PA14_34070) promotor (↓)
REG0171 experimental T6SS0155 insolico protein Global regulator Escherichia coli APEC O1 APECO1_487 (FNR) NC_008563 1455411..1456163 (-) 446534565 APECO1_1756 (VgrG1) (↓)
REG0172 experimental T6SS0152 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_48150 (QslA) NC_008463 4286195..4286536 (-) 489210784 H2-T6SS (PA14_43050) promotor (↑)
REG0173 experimental T6SS0158 experimental protein TCS regulatory pathway Francisella novicida U112 FTN_RS06610 (mglA) NC_008601 1362282..1362899 (+) 489124662 iglC transcription (↓); Unknown (↓)
REG0174 experimental T6SS0158 experimental protein TCS regulatory pathway Francisella novicida U112 FTN_RS02845 (SspA) NC_008601 574840..575472 (+) 500053699 FTN_1465 (pmrA) (↓)
REG0175 experimental T6SS0158 experimental protein TCS-HK Francisella novicida U112 FTN_RS08805 (KdpD) NC_008601 1838601..1841282 (-) 489131611 FTN_1465 (pmrA) (↓)
REG0176 experimental T6SS0158 experimental protein TCS-RR; TCS regulatory pathway Francisella novicida U112 FTN_1465 (pmrA) NC_008601 1553358..1554044 (-) 489108239 FTN_1465 (pmrA) promotor (↓); pdpD promotor (↓); IglA expression (↓)
REG0177 experimental T6SS0158 experimental protein Global regulator; TCS regulatory pathway Francisella novicida U112 FTN_RS06615 (mglB) NC_008601 1362901..1363308 (+) 489112095 IglA expression (↓); T6SS Transciption (↓)
REG0178 experimental T6SS0158 experimental protein TCS regulatory pathway Francisella novicida U112 FTN_0480 (fevR/PigR) NC_008601 486541..486876 (+) 489108070 T6SS Transciption (↓)
REG0179 experimental T6SS1000 insolico protein Global regulator Acinetobacter baumannii ATCC 17978 A1S_0268 (hns) CP000521 292215..292541 (+) A1S_1292 Transcript (↑)
REG0180 experimental T6SS0208 insolico; T6SS0487 insolico protein Global regulator Vibrio cholerae O395 VC0395_RS17530 (TsrA) NC_009457 2598392..2598676 (+) 445982516 T6SS Transciption (↑)
REG0181 experimental T6SS0208 insolico protein Global regulator Vibrio cholerae O395 VC0395_0020/VCA0117 (bEBP/vasH) NC_009456 22315..23907 (-) 446006938 T6SS gene cluster promoter (PVCA0107/VC0395_RS00160) (↓)
REG0182 experimental T6SS0208 insolico protein Global regulator Vibrio cholerae O395 VC0395_A2109 (rpoN) NC_009457 2265078..2266541 (+) 446727517 T6SS gene cluster promoter (PVCA0107/VC0395_RS00160) (↓); hcp promoter (PVCA0017/VC0395_0116) (↓)
REG0183 experimental T6SS0216 insolico protein Global regulator Marinomonas sp. MWYL1 Mmwyl1_1758 (bEBP/vasH) NC_009654 1985170..1986666 (+) 501016781 T6SS gene cluster promoter (PMWYL1196/PMWYL1195) (↓)
REG0184 experimental T6SS0216 insolico protein Global regulator Marinomonas sp. MWYL1 Mmwyl1_2418 (RpoN) NC_009654 2725212..2726687 (+) 501017436 T6SS gene cluster promoter (PMWYL1196/PMWYL1195) (↓)
REG0185 experimental T6SS0225 experimental protein TCS-RR Yersinia pseudotuberculosis IP 31758 YpsIP31758_3980 (ompR) NC_009708 4465260..4465979 (-) 490527984 T6SS-4 promoter (↓)
REG0186 experimental T6SS0225 experimental protein Unknown Yersinia pseudotuberculosis IP 31758 YpsIP31758_3441 (lptD) NC_009708 3878499..3880841 (+) 499505072 YpsIP31758_3980 (ompR) (↓)
REG0187 experimental T6SS0260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII YPK_3449 (RelA) NC_010465 3783755..3785989 (-) 488138165 YPK_1551 (RovM) (↓); YPK_1876 (RovA) (↓)
REG0188 experimental T6SS0260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII YPK_1876 (RovA) NC_010465 2082384..2082815 (+) 488139747 T6SS-4 promoter region (↓); T6SS-4 promoter region (↓)
REG0189 experimental T6SS0260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII YPK_4079 (OxyR) NC_010465 4502978..4503895 (-) 488138270 T6SS-4 promoter region (↓)
REG0190 experimental T6SS0260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII ypk_3425 (RpoS) NC_010465 3759239..3760237 (-) 499505140 T6SS-4 promoter region (↓)
REG0191 experimental T6SS0260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII YPK_1551 (RovM) NC_010465 1713682..1714884 (-) 499506038 T6SS-4 promoter region (↓)
REG0192 experimental T6SS0260 experimental protein carbon storage regulatory pathway Yersinia pseudotuberculosis YPIII YPK_3567 (RovC) NC_010465 3929654..3930397 (+) 170025782 YPK_3567 promotor (↓)
REG0193 experimental T6SS0260 experimental protein carbon storage regulatory pathway Yersinia pseudotuberculosis YPIII YPK_3372 (CsrA) NC_010465 3698608..3698793 (-) 169752121 YPK_3567 (RovC) (↑); YPK_3563 transcript (↑)
REG0194 experimental T6SS0260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII YPK_2462 (HpaR) NC_010465 2695107..2695574 (+) 169751221 T6SS4 promoter (↓)
REG0195 experimental T6SS0256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII YPK_RS08345 (YpsR) NC_010465 1837676..1838413 (+) 488140651 T6SS transcripts (↓)
REG0196 experimental T6SS0256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII YPK_RS03965 (YtbR) NC_010465 900476..901219 (+) 488140447 T6SS transcripts (↓)
REG0197 experimental T6SS0256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII YPK_RS08350 (ypsI) NC_010465 1838406..1839050 (-) 501053391 T6SS transcripts (↓)
REG0198 experimental T6SS0256 insolico; T6SS0260 experimental protein QS regulatory pathway Yersinia pseudotuberculosis YPIII YPK_RS03970 (ytbI) NC_010465 901200..901850 (-) 488144695 T6SS transcripts (↓); T6SS4 transcripts and hcp secretion (↓)
REG0199 experimental T6SS0260 experimental protein TCS-RR Yersinia pseudotuberculosis YPIII YPK_RS00840 (OmpR) NC_010465 223260..223979 (+) 488137706 T6SS4 promoter (↓)
REG0200 experimental T6SS0260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII YPK_RS01520 (ZntR) NC_010465 333471..333896 (+) 488144494 T6SS4 promoter (↓)
REG0201 experimental T6SS0272 experimental protein Global regulator Proteus mirabilis HI4320 PMI0271 (MrpJ) NC_010554 318458..318781 (+) 490365253 PMI0749 (tssA); PMI2990 (idsA/hcp)
REG0202 experimental T6SS0287 experimental protein Unknown Xanthomonas oryzae pv. oryzae PXO99A PXO_RS20535 NC_010717 4488457..4488843 (-) 499576999 Unknown (↓)
REG0203 experimental T6SS0344 experimental protein Global regulator Klebsiella pneumoniae NTUH-K2044 KP1_3314 (hns) NC_012731 3140175..3140582 (+) 238895262 KP1_2392 (TssB) promotor (↑); KP1_2392 (hcp) (↑)
REG0204 experimental T6SS0346 experimental protein TCS-RR Edwardsiella ictaluri 93-146 NT01EI_RS04325 (EsrB) NC_012779 955101..955745 (-) 506350644 T6SS translocon protein EvpC secretion (↓)
REG0205 experimental T6SS0346 experimental protein TCS regulatory pathway Edwardsiella ictaluri 93-146 NT01EI_RS04200 (EsrC) NC_012779 933326..934018 (-) 737638726 T6SS translocon protein EvpC secretion (↓)
REG0206 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2873 (RpoS) NC_013508 3025094..3026080 (-) 502612732 ETAE_0886 (esrB) promoter (↑)
REG0207 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0035 NC_013508 35881..37008 (-) 502609898 ETAE_0886 (esrB) promoter (↑)
REG0208 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0154 (hemB) NC_013508 159867..160889 (+) 502610017 ETAE_0886 (esrB) promoter (↑)
REG0209 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0743 (cdsA) NC_013508 820052..820909 (+) 502610607 ETAE_0886 (esrB) promoter (↑)
REG0210 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2082 (pyrF) NC_013508 2196136..2196858 (-) 502611934 ETAE_0886 (esrB) promoter (↑)
REG0211 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1096 (dapA) NC_013508 1194778..1195659 (+) 502610962 ETAE_0886 (esrB) promoter (↑)
REG0212 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2697 (cysS) NC_013508 2831230..2832615 (-) 502612557 ETAE_0886 (esrB) promoter (↑)
REG0213 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1760 CP001135 1870377..1870535 (+) 267984768 ETAE_0886 (esrB) promoter (↑)
REG0214 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1837 CP001135 1946159..1946284 (-) 267984845 ETAE_0886 (esrB) promoter (↑)
REG0215 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1202 (ugd) NC_013508 1306603..1307769 (+) 502611067 ETAE_0886 (esrB) promoter (↑)
REG0216 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2640 (holA) NC_013508 2779832..2780866 (+) 502612494 ETAE_0886 (esrB) promoter (↑)
REG0217 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1439 (ruvA) NC_013508 1550776..1551384 (+) 502611302 ETAE_0886 (esrB) promoter (↑)
REG0218 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0358 (purA) NC_013508 403538..404836 (+) 502610221 ETAE_0886 (esrB) promoter (↑)
REG0219 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2813 (iscA) NC_013508 2952011..2952334 (-) 491431780 ETAE_0886 (esrB) promoter (↑)
REG0220 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2787 (guaB) NC_013508 2925310..2926776 (-) 502612646 ETAE_0886 (esrB) promoter (↑)
REG0221 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1412 NC_013508 1522924..1523409 (-) 502611274 ETAE_0886 (esrB) promoter (↑)
REG0222 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0430 NC_013508 473075..473755 (-) 502610291 ETAE_0886 (esrB) promoter (↑)
REG0223 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0659 (aceE) NC_013508 731608..734271 (+) 502610523 ETAE_0886 (esrB) promoter (↑)
REG0224 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2773 (mtnN) NC_013508 2910743..2911441 (+) 502612632 ETAE_0886 (esrB) promoter (↑)
REG0225 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2468 NC_013508 2598484..2599356 (-) 504339400 ETAE_0886 (esrB) promoter (↑)
REG0226 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1614 NC_013508 1721332..1722024 (-) 754045576 ETAE_0886 (esrB) promoter (↑)
REG0227 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0994 (Lon) NC_013508 1085063..1087288 (+) 267984010 ETAE_0886 (esrB) promoter (↓)
REG0228 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_3542 (phoU) NC_013508 3747537..3748268 (+) 502613380 ETAE_0886 (esrB) promoter (↓)
REG0229 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_3449 (tpiA) NC_013508 3637381..3638145 (+) 502613286 ETAE_0886 (esrB) promoter (↓)
REG0230 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1655 (prc) NC_013508 1757898..1759940 (+) 735677771 ETAE_0886 (esrB) promoter (↓)
REG0231 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1158 NC_013508 1257412..1258584 (+) 502611022 ETAE_0886 (esrB) promoter (↓)
REG0232 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0772 (tadA) NC_013508 850367..850879 (+) 505698653 ETAE_0886 (esrB) promoter (↓)
REG0233 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0695 (mrcB) NC_013508 766885..769368 (+) 502610560 ETAE_0886 (esrB) promoter (↓)
REG0234 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1170 CP001135 1271304..1271447 (-) 267984186 ETAE_0886 (esrB) promoter (↓)
REG0235 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1562 NC_013508 1668753..1670378 (-) 780104675 ETAE_0886 (esrB) promoter (↓)
REG0236 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_3453 (cpxR) NC_013508 3641204..3641902 (+) 502613290 ETAE_0886 (esrB) promoter (↓)
REG0237 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0263 (mltC) NC_013508 293215..294306 (-) 1392602598 ETAE_0886 (esrB) promoter (↓)
REG0238 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0542 (slt) NC_013508 588958..590886 (+) 502610404 ETAE_0886 (esrB) promoter (↓)
REG0239 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2638 (leuS) NC_013508 2776570..2779152 (+) 502612492 ETAE_0886 (esrB) promoter (↓)
REG0240 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_3207 (rplQ) NC_013508 3390207..3390593 (-) 491439763 ETAE_0886 (esrB) promoter (↓)
REG0241 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1010 (acrB) NC_013508 1099309..1102461 (-) 502610875 ETAE_0886 (esrB) promoter (↓)
REG0242 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1425 (mviN) NC_013508 1535368..1536906 (+) 502611288 ETAE_0886 (esrB) promoter (↓)
REG0243 experimental T6SS0372 experimental protein TCS-RR Edwardsiella tarda EIB202 ETAE_0886 (EsrB) NC_013508 964658..965302 (-) 502610749 Unknown (↓); Unknown (↓)
REG0244 experimental T6SS0372 experimental protein TCS-HK Edwardsiella tarda EIB202 ETAE_2059 (phoP) NC_013508 2172565..2173239 (+) 502611910 ETAE_0886 (EsrB) (↓)
REG0245 experimental T6SS0372 experimental protein Transcription regulator Edwardsiella tarda EIB202 ETAE_3098 (PepA) NC_013508 3260322..3261833 (+) 502612947 ETAE_0886 (esrB) promoter (↑)
REG0246 experimental T6SS0372 experimental protein QS regulatory pathway Edwardsiella tarda EIB202 ETAE_3474 (fabR) NC_013508 3666488..3667159 (-) 502613311 Unknown (↓)
REG0247 experimental T6SS0372 experimental protein Transcription regulator Edwardsiella tarda EIB202 ETAE_1505 (H-NS) NC_013508 1615099..1615506 (-) 505274277 ETAE_2430 (evpB) (↑); evpC promotor (↑)
REG0248 experimental T6SS0464 experimental protein Transcription regulator Escherichia coli 042 EC042_RS26480 (aggR) NC_017627 41080..41877 (-) 446692110 EC042_RS26480 (aggR) promoter (↓); EC042_RS26480 (aggR) promoter (↓)
REG0249 experimental T6SS0464 experimental protein Transcription regulator Escherichia coli 042 EC042_RS18855 (FIS) NC_017626 3772795..3773091 (+) 446385050 EC042_RS26480 (aggR) promoter (↓)
REG0250 experimental T6SS0464 experimental protein Global regulator Escherichia coli 042 EC042_RS06800 (Hns) NC_017626 1376831..1377244 (-) 447210122 EC042_RS26480 (aggR) promoter (↑)
REG0251 experimental T6SS0464 experimental protein Global regulator Escherichia coli 042 EC042_RS03685 (Fur) NC_017626 786918..787364 (-) 446053847 EC042_4532 promoter (↑); EC042_4524 (TssB) promotor (↑)
REG0252 experimental T6SS0464 experimental protein Global regulator Escherichia coli 042 EC042_RS19435 (Dam) NC_017626 3861171..3862007 (-) 446664793 EC042_4532 promoter (↑)
REG0253 experimental T6SS0612 insolico; T6SS0613 insolico; T6SS0611 insolico protein TCS-RR Pseudomonas aeruginosa M18 PAM18_RS12360 (gacA) NC_017548 2625815..2626459 (+) 489180874 hsiA1 operon transcript (↓); hsiA2 operon transcript (↓); hsiA3 operon transcript (↓)
REG0254 experimental T6SS0788 experimental protein Transcription regulator Aeromonas hydrophila SSU VasH DQ667172 15458..16996 (+) 110277136 hcp expression (↓)
REG0255 experimental T6SS0788 experimental protein QS regulatory pathway Aeromonas hydrophila SSU ahyI DQ398101 843..1466 (+) 89027174 ahyR (↓)
REG0256 experimental T6SS0788 experimental protein QS regulatory pathway Aeromonas hydrophila SSU ahyR DQ398101 1..783 (-) 89027173 hcp and vgrG2 expression (↓)
REG0257 experimental T6SS0794 experimental protein Tpp Vibrio alginolyticus EPJS VEPGS_0614 (PppA) FJ790777 15765..16880 (+) 225382180 LuxR (↓)
REG0258 experimental T6SS0794 experimental protein Tpp Vibrio alginolyticus EPJS VEPGS_0606 (PpkA2) FJ790777 3227..5377 (-) 225382172 LuxR (↓); VEPGS_0610 (DotU2) (↓)
REG0259 experimental T6SS0794 experimental protein Tpp Vibrio alginolyticus EPJS VEPGS_0607 (Fha2) FJ790777 5690..6775 (+) 225382173 VEPGS_0610 (DotU2) (↓)
REG0260 experimental T6SS0794 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS EPGS_00471 (VtsR) FJ790777 - () LuxO (↓)
REG0261 experimental T6SS0793 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS EPGS_00471 (VtsR) FJ790776 - () LuxO (↑)
REG0262 experimental T6SS0794 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS luxR FJ790777 - () T6SS2 transcript and expression (↓)
REG0263 experimental T6SS0793 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS luxR FJ790776 - () T6SS1 transcript and expression (↑)
REG0264 experimental T6SS0793 experimental protein Tpp; QS regulatory pathway Vibrio alginolyticus EPJS VEPGS_0621 (pppA) FJ790776 23577..24245 (+) 225382187 Unknown (↑); T6SS1 transcript (↑); hcp1 transcript (↓)
REG0265 experimental T6SS0793 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS luxS FJ790776 - () hcp1 transcript (↓)
REG0266 experimental T6SS0793 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS LuxO FJ790776 - () hcp1 transcript (↓)
REG0267 experimental T6SS0794 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS LuxO FJ790777 - () Unknown (↑)
REG0268 experimental T6SS0793 experimental protein Transcription regulator Vibrio alginolyticus EPJS rpoN FJ790776 - () T6SS1 transcript (↓)
REG0269 experimental T6SS0793 experimental protein Transcription regulator Vibrio alginolyticus EPJS VasH FJ790776 - () T6SS1 transcript (↓)
REG0270 experimental T6SS0904 experimental protein Transcription regulator Escherichia coli strain TW-XM CXG97_03740 (Fur) NZ_CP025328 729474..729920 (-) 446053847 T6SS1 (TssB) promotor (↑)
REG0271 experimental T6SS0931 experimental protein Global regulator Escherichia coli 17-2 H1D38_08255 (fur) JACEFV010000001 1744748..1745194 (-) MBA2233871.1 sciH promotor (↑)
REG0272 experimental T6SS0931 experimental protein Global regulator Escherichia coli 17-2 H1D38_12840 (Dam) JACEFV010000002 105877..106713 (+) MBA2234741.1 sciH promotor (↑)
REG0273 experimental T6SS0937 experimental protein TCS-RR Escherichia coli DE719 W817_21870 (CpxR) NZ_CP007149 4360812..4361510 (-) 446956464 hcp2B promoter (↓)
REG0274 experimental T6SS0937 experimental protein TCS Escherichia coli DE719 W817_01610 (NplE) NZ_CP007149 214947..215657 (+) 446161331 W817_RS21690 (CpxA) (↓)
REG0275 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_21538 (LuxR) AAPS01000053 13551..14165 (-) 91187814 T6SS2 transcripts (↓)
REG0276 experimental T6SS0939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 V12G01_19736 (TfoX) AAPS01000019 47689..48276 (-) 91189146 T6SS2 transcripts (↓)
REG0277 experimental T6SS0939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 V12G01_20658 (TfoY) AAPS01000015 63783..64190 (+) 91189474 T6SS transcripts (↓)
REG0278 experimental T6SS0939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 V12G01_20201 (H-NS) AAPS01000015 63783..64190 (+) 91189474 VaT6SS1 transcripts (↑)
REG0279 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01-18672 (vqsA) AAPS01000003 114208..115086 (+) 91191289 V12G01-21538 (luxR) promoter (↓); V12G01-14830 (aphA) promoter (↓); V12G01-18672 (vqsA) promotor (↓)
REG0280 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_10813 (AsnC) AAPS01000004 181050..181484 (-) 91191052 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0281 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_02325 (HP) AAPS01000004 115263..116411 (+) 91190993 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0282 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_01665 (HP) AAPS01000007 185299..185712 (+) 91190406 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0283 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_06711 (HP) AAPS01000024 47707..48585 (-) 91188835 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0284 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_16177 (MetR) AAPS01000023 58420..59331 (-) 91188901 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0285 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_02620 (SoxR) AAPS01000004 181050..181484 (-) 91191052 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0286 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_21538 (luxR) AAPS01000053 13551..14165 (-) 91187814 V12G01-18672 (vqsA) promotor
REG0287 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01-14830 (aphA) AAPS01000027 42305..42880 (+) 91188695 V12G01-18672 (vqsA) promotor
REG0288 experimental T6SS0002 experimental protein TCS-RR Vibrio cholerae O1 biovar El Tor str. N16961 VCA1552_03277/VCA0566 (VxrB) NC_002506 504728..505384 (+) 446737785 Unknown (↑)
REG0289 experimental T6SS0002 experimental protein c-di-GMP regulatory pathway Vibrio cholerae O1 biovar El Tor str. N16961 VCA0933 (CspV) NC_002506 886068..886280 (+) 446027150 Unknown (↓)
REG0290 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_01380 (VdcA/ycdT) NZ_CP024867 1482426..1483715 (+) 446892247 the levels of c-di-GMP (↑)
REG0291 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_02536 (CdpA/YfgF) NZ_CP024867 2739669..2742158 (-) 446417730 the levels of c-di-GMP (↓)
REG0292 experimental T6SS1112 experimental protein Global regulator Vibrio cholerae A1552 VCA1552_02898 (VasH) NZ_CP024868 128889..130481 (+) 446006938 VCA1552_00900 (TfoX) (↓)
REG0293 experimental T6SS1112 experimental protein Global regulator Vibrio cholerae A1552 VCA1552_00351 (HapR) NZ_CP024867 340447..341058 (-) 446262243 Unknown; Hcp expression and secretion
REG0294 experimental T6SS1112 experimental protein Transcription regulator Vibrio cholerae A1552 VCA1552_RS04890 (ihfA) NZ_CP024867 1028170..1028466 (+) 447152004 Hcp secretion (↓)
REG0295 experimental T6SS1112 experimental protein Transcription regulator Vibrio cholerae A1552 VCA1552_RS08565 (ihfB) NZ_CP024867 1839353..1839631 (-) 446089486 Hcp secretion (↓)
REG0296 experimental T6SS1112 experimental protein QS regulatory pathway Vibrio cholerae A1552 VCA1552_RS03895 (LuxO) NZ_CP024867 818142..819509 (+) 487814784 Hcp expression and secretion (↑)
REG0297 experimental T6SS1112 experimental protein QS regulatory pathway Vibrio cholerae A1552 VCA1552_RS17020 (cqsa) NZ_CP024868 455238..456407 (-) 446962656 Hcp expression and secretion (↓)
REG0298 experimental T6SS1112 experimental protein QS regulatory pathway Vibrio cholerae A1552 VCA1552_RS01665 (LuxS) NZ_CP024867 319588..320106 (+) 447052971 Hcp expression and secretion (↓)
REG0299 experimental T6SS1112 experimental protein QS regulatory pathway Vibrio cholerae A1552 VCA1552_RS00505 (hfq) NZ_CP024867 92673..92936 (+) 446974616 VCA1552_00351 (HapR) (↑)
REG0300 experimental T6SS1112 experimental protein Global regulator Vibrio cholerae A1552 VCA1552_RS11610 (RpoN) NZ_CP024867 2488023..2489486 (+) 446727517 Hcp expression and secretion (↓)
REG0301 experimental T6SS1112 experimental protein QS regulatory pathway Vibrio cholerae A1552 VCA1552_RS12025 (crp) NZ_CP024867 2558371..2559003 (+) 446164894 Hcp expression and secretion (↓)
REG0302 experimental T6SS1112 experimental protein QS regulatory pathway; cAMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS12925 (cya) NZ_CP024867 2747346..2749877 (-) 447072406 VCA1552_RS12025 (crp) (↓)
REG0303 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway; QS regulatory pathway; Global regulator Vibrio cholerae A1552 VC0396/VCA1552_00154 (QstR) NZ_CP024867 149920..150564 (-) 447111060 TssB/ TfoY transcripts (↓); VC0396/VCA1552_00154 (QstR) (↓); T6SS transcripts (↓)
REG0304 experimental T6SS1112 experimental protein Global regulator Vibrio cholerae A1552 VCA1552_00900 (TfoX) NZ_CP024867 952868..953476 (+) 487807468 VC0396/VCA1552_00154 (QstR) (↓)
REG0305 experimental T6SS1112 experimental protein QS regulatory pathway; c-di-GMP regulatory pathway; Global regulator Vibrio cholerae A1552 VCA1552_00154 (QstR) NZ_CP024867 149920..150564 (-) 447111060 Unknown (↓)
REG0306 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_01510 (TfoY) NZ_CP024867 1636980..1637567 (+) 446282733 Unknown (↓)
REG0307 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS06160 (lonA) NZ_CP024867 1315238..1316887 (+) 446116573 VCA1552_01510 (TfoY) (↑)
REG0308 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS10420 (cdgL) NZ_CP024867 2215844..2217361 (-) 446975354 the levels of c-di-GMP (↓)
REG0309 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS04310 (cdgK) NZ_CP024867 901594..903063 (+) 487807420 the levels of c-di-GMP (↓)
REG0310 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS04130 (cdgH) NZ_CP024867 861187..863208 (+) 446848493 the levels of c-di-GMP (↓)
REG0311 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS02130 (rocS) NZ_CP024867 425233..427287 (-) 447034155 the levels of c-di-GMP (↑)
REG0312 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS12850 (cdgJ) NZ_CP024867 2733319..2734545 (-) 446210986 the levels of c-di-GMP (↑)
REG0313 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS17835 (cdgD) NZ_CP024868 633312..635195 (+) 446210820 the levels of c-di-GMP (↓)
REG0314 experimental T6SS0790 experimental protein Global regulator Vibrio cholerae V52 TfoY NZ_AAKJ02000013 - () Unknown (↓)
REG0315 experimental T6SS0790 experimental protein Global regulator Vibrio cholerae V52 VCV52_1108 (TfoX) NZ_KQ410501 68827..69435 (-) 487807468 Unknown (↓)
REG0316 experimental T6SS0790 experimental protein Global regulator Vibrio cholerae V52 VCV52_RS01020 (VasH) NZ_KQ410497 212259..213851 (-) 446006947 Unknown (↓)
REG0317 experimental T6SS0790 experimental protein Global regulator Vibrio cholerae V52 VCV52_RS13040 (rpoN) NZ_KQ410502 216932..218395 (-) 446727517 Unknown (↓)
REG0318 experimental T6SS0791 experimental protein TCS-HK Edwardsiella tarda PPD130/91 Y113_RS04835 (esrC) AY424360 20632..23367 (+) 1624663318 T6SS transcripts (↓)
REG0319 experimental T6SS0791 experimental protein TCS-RR Edwardsiella tarda PPD130/91 Y113_RS04830 (esrB) AY424360 19991..20635 (-) 502610749 EvpA and EvpC protein concentration (↓)
REG0320 experimental T6SS0002 experimental protein Transcription regulator Vibrio cholerae O1 biovar El Tor str. N16961 VC_A0122 NC_002506 137379..137621 (+) 9657509 hcp-2 expression (↓)
REG0321 experimental T6SS1170 experimental protein QS regulatory pathway Pectobacterium brasiliense 1692 GT391_RS06470 (expR1) NZ_CP047495 1453704..1455596 (+) 746272689 T6SS transcripts (↓)
REG0322 experimental T6SS1170 experimental protein QS regulatory pathway Pectobacterium brasiliense 1692 GT391_RS06405 (expI) NZ_CP047495 1436931..1437581 (-) 497970044 GT391_RS06470 (expR1) (↓)
REG0323 experimental T6SS1170 experimental protein TCS-HK Pectobacterium brasiliense 1692 GT391_RS16925 (phoP) NZ_CP047495 3795787..3796476 (-) 497961604 GT391_RS06470 (expR1) (↑)
REG0324 experimental T6SS1276 experimental protein QS regulatory pathway Burkholderia cenocepacia strain K56-2 WQ49_05050 (cepR) LAUA01000002 545988..546707 (-) 815852483 T6SS promotor (P (BCAL0340) ) (↓)
REG0325 experimental T6SS1276 experimental protein QS regulatory pathway Burkholderia cenocepacia strain K56-2 WQ49_20245 (cciR) LAUA01000016 843677..844378 (+) 815850423 Unknown (↑)
REG0326 experimental T6SS1276 experimental protein TCS-RR Burkholderia cenocepacia strain K56-2 WQ49_19595/BCAM0379 (atsR) LAUA01000016 710895..712715 (+) 815849700 T6SS transcripts (↑); T6SS expression (↑)
REG0327 experimental T6SS1276 experimental protein QS regulatory pathway Burkholderia cenocepacia strain K56-2 WQ49_05060 (cepI) LAUA01000002 547435..548043 (+) 815852485 T6SS expression (↓)
REG0328 experimental T6SS1276 experimental protein QS regulatory pathway Burkholderia cenocepacia strain K56-2 WQ49_20250 (cciI) LAUA01000016 844665..845255 (+) 815850424 T6SS expression (↓)
REG0329 experimental T6SS0719 experimental protein Transcription regulator Vibrio parahaemolyticus BB22OP VPBB_RS05425 (H-NS) NC_019955 1170475..1170882 (-) 505109423 VgrG1 expression and secretion (↑)
REG0330 experimental T6SS1266 insolico; T6SS1267 insolico protein TCS-RR Pseudomonas chlororaphis subsp. aureofaciens 30-84 Pchl3084_4333 (gacS) NZ_CM001559 5113748..5116501 (+) 496335944 Pchl3084_3491 (gacA) (↓)
REG0331 experimental T6SS1266 insolico; T6SS1267 insolico protein TCS-HK Pseudomonas chlororaphis subsp. aureofaciens 30-84 Pchl3084_3491 (gacA) NZ_CM001559 4134794..4135435 (-) 496335231 Pchl3084_5419 (rsmY)promotor (↓); Pchl3084_1190 (rsmZ)promotor (↓); Pchl3084_1189 (rpoS)transcript (↓)
REG0332 experimental T6SS1269 experimental protein TCS-RR Pseudomonas aeruginosa CHA GacS* - - () hcp1 expression and secretion (↑)
REG0333 experimental T6SS1269 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa CHA rsmA - - () hcp1 expression and secretion (↑)
REG0334 experimental T6SS1041 insolico protein IAA regulatory pathway Pseudomonas savastanoi pv savastanoi NCPPB 3335 PSA3335_RS05390 (iaaM) NZ_CP008742 1090961..1092634 (-) 488619197 The transcript levels of vgrG (↓)
REG0335 experimental T6SS1041 insolico protein IAA regulatory pathway Pseudomonas savastanoi pv savastanoi NCPPB 3335 PSA3335_RS05385 (iaaH) NZ_CP008742 1089578..1090918 (-) 488619198 The transcript levels of vgrG (↓)
REG0336 experimental T6SS1291 experimental protein TCS-RR Salmonella enterica subsp. enterica serovar Typhimurium strain ATCC 14028 BWP10_01550 (ssrB) MTFW01000001 296600..299362 (+) 1145677935 sciS/TssM transcription (↑)
REG0337 experimental T6SS1272 experimental protein TCS-RR Edwardsiella tarda PPD130/91 Y113_RS04830 (esrB) NZ_JACQ01000009 19991..20635 (+) 502610749 the expression of evpA and evpC (↓)
REG0338 experimental T6SS1214 experimental protein TCS-RR Klebsiella pneumoniae strain Kp52.145 BN49_2224 (phoQ) NZ_FO834906 2324171..2325637 (-) 490249900 TssB transcription (↓)
REG0339 experimental T6SS1214 experimental protein TCS-HK Klebsiella pneumoniae strain Kp52.145 BN49_2225 (phoP) NZ_FO834906 2325637..2326308 (-) 490252783 BN49_2224 (phoQ) (↓)
REG0340 experimental T6SS1214 experimental protein TCS regulatory pathway Klebsiella pneumoniae strain Kp52.145 BN49_RS29275 (mgrB) NZ_FO834906 3583038..3583181 (-) 489000713 phoPQ (↑)
REG0341 experimental T6SS1214 experimental protein TCS-RR Klebsiella pneumoniae strain Kp52.145 BN49_3854 (rcsB) NZ_FO834906 4066268..4066918 (+) 489002368 phoPQ (↑)
REG0342 experimental T6SS1214 experimental protein Global regulator Klebsiella pneumoniae strain Kp52.145 BN49_3310 (h-ns) NZ_FO834906 3427636..3428043 (+) 488999426 TssB transcription (↑)
REG0343 experimental T6SS1214 experimental protein Global regulator Klebsiella pneumoniae strain Kp52.145 BN49_1760 (fur) NZ_FO834906 1826878..1827330 (-) 514077307 TssB transcription (↓)
REG0344 experimental T6SS1214 experimental protein QS regulatory pathway Klebsiella pneumoniae strain Kp52.145 BN49_4862 (hfq) NZ_FO834906 5173711..5174019 (-) 488974767 TssB transcription (↓)
REG0345 experimental T6SS1214 experimental protein Global regulator Klebsiella pneumoniae strain Kp52.145 BN49_0508 (rpoN) NZ_FO834906 533564..534997 (-) 489007850 TssB transcription (↓)
REG0346 experimental T6SS1214 experimental protein Global regulator Klebsiella pneumoniae strain Kp52.145 BN49_1023 (rpoS) NZ_FO834906 1060230..1060235 (+) 489004494 TssB transcription (↓)
REG0347 experimental - protein Global regulator sdiA - - () ENC_07270 transcript (↓)
REG0348 experimental T6SS0929 experimental protein Tpp Serratia marcescens Db10 SMDB11_2275/SMA2275 (PpkA) HG326223 2399154..2400599 (+) 560174118 SMDB11_2267/SMA2267 (Fha) (↓); SMDB11_2267/SMA2267 (Fha) (↑)
REG0349 experimental T6SS0929 experimental protein Tpp Serratia marcescens Db10 SMDB11_2267/SMA2267 (Fha) HG326223 2388490..2390232 (+) 560174110 Unknown (↓)
REG0350 experimental T6SS1164 experimental protein Single regulator Acinetobacter baumannii AbCAN2 F9K57_RS04510 (VgrGi) NZ_CP045428 925473..928592 (+) 1797381381 T6SS structure (↑)
REG0351 experimental T6SS0431 insolico; T6SS0432 insolico protein TCS-RR Pseudomonas brassicacearum subsp. brassicacearum NFM421 PSEBR_RS22825 (GacS) NC_015379 5188012..5190762 (+) 503459407 hcp1 transcript (↓)
REG0352 experimental T6SS0431 insolico; T6SS0432 insolico protein TCS-RR Pseudomonas brassicacearum subsp. brassicacearum NFM421 NC_015379 5188012..5190762 (+) 503459407 hcp2 transcript (↓)
REG0353 experimental T6SS0157 experimental protein QS regulatory pathway Aeromonas hydrophila subsp. hydrophila ATCC 7966 AHA_1842 (VasH) NC_008570 2010521..2012059 (+) 117617496 T6SS gene cluster promoter (PAHA1826) (↓)
REG0354 experimental T6SS0157 experimental protein Global regulator Aeromonas hydrophila subsp. hydrophila ATCC 7966 AHA_3923 (rpoN) NC_008570 4350676..4352115 (-) 117618923 T6SS gene cluster promoter (PAHA1826) (↓)
REG0355 experimental T6SS1280 experimental; T6SS1281 experimental protein QS regulatory pathway Vibrio coralliilyticus OCN008 N779_15250 (VtpR) AVOO01000045 7579..8184 (-) 536747482 Unknown (↓)
REG0356 experimental T6SS1037 insolico protein TCS-RR Dickeya zeae EC1 W909_RS11820 (VfmH) NZ_CP006929 2699617..2701098 (+) 515507611 T6SS transcripts (↓)
REG0357 experimental T6SS1034 experimental protein TCS-HK Escherichia coli PCN033 PPECC33_RS11180 (BaeS) NZ_CP006632 2271464..2272867 (+) 446597798 PPECC33_RS11185 (BaeR) (↓)
REG0358 experimental T6SS1034 experimental protein TCS-RR Escherichia coli PCN033 PPECC33_RS11185 (BaeR) NZ_CP006632 2272864..2273586 (+) 446060022 T6SS promotor (↓)
REG0359 experimental T6SS0343 insolico protein Global regulator Burkholderia glumae BGR1 bglu_1g09700 (tepR) NC_012724 1045102..1046502 (-) Unknown (↓)
REG0360 experimental T6SS0195 insolico protein Global regulator ACX61_19655 (tetR2) NZ_CP012007 144108..144677 (+) 446104352 hcp secretion (↑)
REG0361 experimental T6SS0195 insolico protein Global regulator ACX61_19615 (tetR1) NZ_CP012007 139526..140098 (+) 487938137 hcp secretion (↑)
REG0362 experimental T6SS1034 experimental protein TCS-RR Escherichia coli PCN033 PPECC33_RS11945 (rcsB) NZ_CP006632 2429320..2429970 (+) 446984661 T6SS transcription (↓)

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Related T6SS Regulator type Regulatory pathway Organism                 Locus tag (Gene) Genome accession Coordinate (Strand) NCBI ID Target (Regulation)
REG0001 experimental T6SS0529 insolico; T6SS0530 insolico protein Transcription regulator Vibrio furnissii NCTC 11218 vfu_A02134 (ihfA) NC_016602 2226951..2227244 (-) 490864172 tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓)
REG0002 experimental T6SS0529 insolico; T6SS0530 insolico protein Transcription regulator Vibrio furnissii NCTC 11218 vfu_A02422 (ihfB) NC_016602 2516092..2516376 (-) 490864456 tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓)
REG0003 experimental T6SS1264 experimental protein TCS-HK Serratia marcescens RM66262 RT90_01105 (rcsC) JWLO01000001 232638..235499 (+) 735006326 RT90_01115 (rcsB) (↑)
REG0004 experimental T6SS1264 experimental protein TCS-RR Serratia marcescens RM66262 RT90_01115 (rcsB) JWLO01000001 235561..236211 (-) 735006328 vgrG promoter (↓)
REG0005 experimental T6SS1264 experimental protein TCS regulatory pathway Serratia marcescens RM66262 RT90_16255 (wecG) JWLO01000003 92056..92796 (+) 735005313 RT90_01105 (rcsC) (↑)
REG0006 experimental T6SS1033 experimental protein Tpp Serratia sp FS14 L085_RS13655 (ppka) NZ_CP005927 3028273..3029718 (-) 763151328 Unknown (↓)
REG0007 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK PA4740/Y880_04683 (pnp) NZ_CP020659 4637120..4639225 (-) 489185761 PA0527.1 (RsmY) (↑); PA3621.1 (RsmZ) (↑)
REG0010 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK Y880_06257 (rsmA) NZ_CP020659 6213838..6214644 (-) 510932573 PA4492 mRNA (↑)
REG0011 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK Y880_05180 (rmsF) NZ_CP020659 5147809..5148024 (-) 489186811 tssA1 expression (↑)
REG0012 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein TCS-RR Pseudomonas aeruginosa PAK Y880_02189 (gacA/uvrY) NZ_CP020659 2199690..2200334 (-) 510933056 hcp expression (↓)
REG0013 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein TCS regulatory pathway Pseudomonas aeruginosa PAK Y880_03649 (suhB) NZ_CP020659 3616623..3617438 (+) 489183406 Y880_02189 (gacA/uvrY) (↓)
REG0014 experimental T6SS0929 experimental protein Tpp Serratia marcescens Db10 SMDB11_2275 (PpKA) HG326223 2399154..2400599 (+) 560174118 SMDB11_2267 (FHA) (↓)
REG0015 experimental T6SS0929 experimental protein Tpp Serratia marcescens Db10 SMDB11_2268 (PppA) HG326223 2390232..2391005 (+) 560174111 SMDB11_2267 (FHA) (↑)
REG0016 experimental T6SS0929 experimental protein Tpp Serratia marcescens Db10 SMDB11_2269 (RtkS) HG326223 2391034..2392020 (+) 560174112 SMDB11_2275 (PpKA) (↓)
REG0017 experimental T6SS0929 experimental protein Tpp Serratia marcescens Db10 SMDB11_2256 (TagF) HG326223 2380702..2381421 (+) 560174099 Unknown (↑)
REG0018 experimental T6SS0003 experimental; T6SS0004 experimental; T6SS0005 experimental protein Global regulator Pseudomonas aeruginosa PAO1 PA4462 (RpoN) NC_002516 4992870..4994363 (+) 15599658 PA1512 (hcpA) promotor (↓); PA5267 (hcpB) promotor (↓)
REG0019 experimental T6SS1001 insolico protein QS regulatory pathway Pectobacterium carotovorum subsp carotovorum PC1 PC1_3721 (Hfq) CP001657 4199890..4200189 (-) 251756660 hcp expression (↓)
REG0021 experimental T6SS1168 experimental protein Unknown Vibrio cholerae C6706 GPY04_RS11195 (CytR) NZ_CP046844 2449479..2450486 (-) 446146597 Unknown (↓)
REG0022 experimental T6SS1168 experimental protein QS regulatory pathway Vibrio cholerae C6706 GPY04_RS03590 (TfoX) NZ_CP046844 777344..777952 (+) 487807468 Unknown (↓)
REG0023 experimental T6SS1168 experimental protein QS regulatory pathway Vibrio cholerae C6706 GPY04_RS00870 (HapR) NZ_CP046844 164935..165546 (-) 446262243 Unknown (↓)
REG0024 experimental T6SS1168 experimental protein Global regulator Vibrio cholerae C6706 GPY04_RS13335/VC0070 (tsrA) NZ_CP046844 2888303..2888587 (+) 445982516 T6SS transcripts (↑)
REG0029 experimental T6SS1168 experimental protein QS regulatory pathway Vibrio cholerae C6706 GPY04_RS15835 (luxO) NZ_CP046844 273631..274983 (-) 446367907 VC0070 (tsrA) (↑)
REG0030 experimental T6SS1168 experimental protein Global regulator Vibrio cholerae C6706 GPY04_RS13825 (QstR) NZ_CP046844 2994333..2994977 (-) 447111060 Unknown (↓)
REG0031 experimental T6SS1168 experimental protein Global regulator Vibrio cholerae C6706 GPY04_RS15835 (luxO) NZ_CP046844 2994333..2994977 (-) 447111060 Unknown (↓)
REG0032 experimental T6SS1168 experimental protein QS regulatory pathway Vibrio cholerae C6706 GPY04_RS15835 (luxO) NZ_CP046845 273631..274983 (-) 446367907 GPY04_RS00870 (hapR) (↑)
REG0033 experimental T6SS1168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 GPY04_RS01040 (ChiS) NZ_CP046844 210606..213995 (-) 446410424 Necessory for TfoX/TfoR (↓)
REG0034 experimental T6SS1168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 GPY04_RS03200 (chiA2) NZ_CP046844 692014..695280 (+) 487807405 GPY04_RS01040 (ChiS) (↓)
REG0035 experimental T6SS1168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 GPY04_RS07700 (chiA1) NZ_CP046844 1709613..1712153 (-) 446755770 GPY04_RS01040 (ChiS) (↓)
REG0036 experimental T6SS1112 experimental protein Unknown Vibrio cholerae A1552 VC1920/VCA1552_01695 (LonA) NZ_CP024867 1845472..1847832 (-) 446970355 Unknown (↑)
REG0037 experimental T6SS1211 insolico; T6SS1212 insolico; T6SS1213 insolico protein c-di-GMP regulatory pathway Pseudomonas aeruginosa PAK Y880_05519 (dgcP) NZ_CP020659 5487251..5489266 (-) 489205065 the levels of c-di-GMP (↓)
REG0038 experimental T6SS1041 insolico protein c-di-GMP regulatory pathway Pseudomonas savastanoi pv savastanoi NCPPB 3335 PSA3335_06200 (dgcP) NZ_CP008742 1344347..1346692 (+) 488618048 the levels of c-di-GMP (↓)
REG0039 experimental T6SS0002 experimental protein Global regulator Vibrio cholerae O1 biovar El Tor str. N16961 VC_RS13930 (VasH) NC_002506 128790..130382 (+) 446006938 VCA0017 (hcp-2) transcript (↓)
REG0040 experimental T6SS0003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 PA0592 (RsmA) NC_002516 650575..651381 (-) 15595789 FHA (PA0081) (↑)
REG0041 experimental T6SS0003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 PA5183a (RsmN) NC_002516 5836470..5836685 (-) 554753081 FHA (PA0081) (↑); PA3487 (pldA) expression (↑)
REG0042 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0075 (PppA) NC_002516 90106..90834 (-) 15595273 PA0081 (Fha-1/TagH) (↑)
REG0043 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0074 (PpkA) NC_002516 87000..90098 (-) 15595272 PA0081 (Fha-1/TagH) (↓)
REG0047 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0072 (TagS) NC_002516 85085..86284 (-) 15595270 PA0073 (TagT) (↓)
REG0048 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0070 (TagQ) NC_002516 82404..83318 (-) 15595268 PA0071 (tagR) (↓)
REG0049 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0073 (TagT) NC_002516 86284..87003 (-) 15595271 PA0072 (TagS) (↓)
REG0050 experimental T6SS0003 experimental protein Unknown Pseudomonas aeruginosa PAO1 PA2492 (MexT) NC_002516 2807469..2808512 (+) 15597688 T6SS transcripts (↑)
REG0051 experimental T6SS0003 experimental protein Unknown Pseudomonas aeruginosa PAO1 PA1006 NC_002516 1090606..1090857 (+) 15596203 T6SS transcripts (↓)
REG0052 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0071 (tagR) NC_002516 83380..85092 (-) 15595269 PA0074 (PpkA) (↓)
REG0053 experimental T6SS0003 experimental protein Global regulator Pseudomonas aeruginosa PAO1 PA4856 (RetS) NC_002516 5452150..5454978 (+) 15600049 hcp1 (PA0085) expression and secretion (↑)
REG0054 experimental T6SS0003 experimental protein Global regulator Pseudomonas aeruginosa PAO1 PA3974 (LadS) NC_002516 4453289..4455676 (-) 15599169 hcp1 (PA0085) expression and secretion (↓)
REG0056 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0076 (TagF) NC_002516 90844..91524 (-) 15595274 hcp1 (PA0086) secretion (↑)
REG0057 experimental T6SS0003 experimental protein Tpp Pseudomonas aeruginosa PAO1 PA0081 (Fha-1/TagH) NC_002516 98263..99756 (-) 15595279 Unknown (↓); clpV (↓)
REG0058 experimental T6SS0003 experimental protein Unknown Pseudomonas aeruginosa PAO1 PA2976 (RNase E) NC_002516 3332881..3336054 (+) 15598172 PA0077 (icmF1) expression (↑)
REG0061 experimental T6SS0004 experimental protein Unknown Pseudomonas aeruginosa PAO1 PA0996 (pqsA) NC_002516 1078462..1080015 (+) 15596193 T6SS transcripts
REG0062 experimental T6SS0004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 PA1244 (QslA) NC_002516 1348060..1348401 (-) 15596441 H2-T6SS (PA1656) promotor (↑)
REG0063 experimental T6SS0004 experimental protein Transcription regulator Pseudomonas aeruginosa PAO1 PA4778 (CueR) NC_002516 5366257..5366655 (+) 15599972 tssA2 (-173 to -140 relative to the ATG start codon) (↓); hcp2 (-208 to -159 relative to the ATG start codon) (↓)
REG0064 experimental T6SS0004 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 PA4856 (RetS) NC_002516 5366257..5366655 (+) 15599972 H2-T6SS (↑)
REG0065 experimental T6SS0004 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 PA1430 (LasR) NC_002516 1558171..1558890 (+) 15596627 H2-T6SS promotor P (hsiA2) (↓)
REG0066 experimental T6SS0004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 PA3476 (rhlI) NC_002516 3889139..3889744 (-) 15598672 PA3477 (RhlR) (↓)
REG0067 experimental T6SS0004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 PA3477 (RhlR) NC_002516 3889925..3890650 (-) 15598673 T6SS transcript (↓)
REG0068 experimental T6SS0004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 PA4764 (Fur) NC_002516 5351675..5352079 (-) 15599958 H2-T6SS Transcription (↑)
REG0069 experimental T6SS0004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 PA4462 (rpoN) NC_002516 4992870..4994363 (+) 15599658 T6SS transcript (↑)
REG0070 experimental T6SS0004 experimental; T6SS0005 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 pa1663 (sfa2) NC_002516 1813395..1814906 (+) 15596860 PA4462 (rpoN) (↑); T6SS transcript (↑); T6SS transcript (↓)
REG0071 experimental T6SS0006 insolico protein Global regulator Escherichia coli O157:H7 str. EDL933 Z4049 (RpoS) NC_002655 3654380..3655372 (-) 446003635 Z1921 (KatN) (↓)
REG0072 experimental T6SS0006 insolico protein Global regulator Escherichia coli O157:H7 str. EDL933 Z5519 (OxyR) NC_002655 5033893..5034810 (+) 446948683 Z1921 (KatN) (↓)
REG0073 experimental T6SS0006 insolico protein Global regulator Escherichia coli O157:H7 str. EDL933 Z2013 (hns) NC_002655 1829490..1829903 (-) 447210122 Z0264 (hcp-2) (↑)
REG0074 experimental T6SS0014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 PP_4373 (FleQ) NC_002947 4963882..4965357 (-) 26991062 K1-T6SS (hcp1) expression (↑)
REG0075 experimental T6SS0014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 PP_0952 (RopN) NC_002947 1094567..1096060 (-) 26987688 PP_4373 (FleQ) (↑)
REG0076 experimental T6SS0014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 PP_0914 (BifA) NC_002947 1055990..1058071 (-) 26987650 the levels of c-di-GMP (↓)
REG0077 experimental T6SS0016 experimental protein Tpp Agrobacterium tumefaciens str. C58 Atu4335 (Fha/TagH) NC_003063 1467064..1468263 (-) 499280697 Unknown (↓)
REG0078 experimental T6SS0016 experimental protein Tpp Agrobacterium tumefaciens str. C58 Atu4330 (PpkA) NC_003063 1458366..1459271 (-) 737274050 Unknown (↓)
REG0079 experimental T6SS0016 experimental protein Tpp Agrobacterium tumefaciens str. C58 Atu4331 (TagF-PppA) NC_003063 1459258..1460673 (-) 159186120 Fha (Atu4335) (↑)
REG0080 experimental T6SS0016 experimental protein c-di-GMP regulatory pathway Agrobacterium tumefaciens str. C58 Atu2091 NC_003063 2054055..2054864 (-) 159185045 the levels of c-di-GMP (↑)
REG0081 experimental T6SS0016 experimental protein c-di-GMP regulatory pathway Agrobacterium tumefaciens str. C58 Atu5372 NC_003063 363152..364387 (+) 16119598 the levels of c-di-GMP (↑)
REG0082 experimental T6SS0016 experimental protein c-di-GMP regulatory pathway Agrobacterium tumefaciens str. C58 Atu1257 (DgcA) NC_003063 1244567..1245814 (-) 159184686 the levels of c-di-GMP (↑)
REG0083 experimental T6SS0016 experimental protein c-di-GMP regulatory pathway Agrobacterium tumefaciens str. C58 Atu2179 (DgcC) NC_003063 2154605..2155744 (-) 159185090 the levels of c-di-GMP (↑)
REG0084 experimental T6SS0016 experimental protein TCS-HK Agrobacterium tumefaciens str. C58 chvG NC_003062 34679..36469 (-) chvI (↓)
REG0085 experimental T6SS0016 experimental protein TCS-RR Agrobacterium tumefaciens str. C58 chvI NC_003062 36525..37250 (-) The intergenic region of the imp and hcp operons (↓)
REG0086 experimental T6SS0016 experimental protein TCS regulatory pathway Agrobacterium tumefaciens str. C58 exoR NC_003062 1702398..1703192 (-) chvG (↑)
REG0087 experimental T6SS0023 experimental protein Global regulator Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 STM1751 (H-NS) NC_003197 1847277..1847690 (+) 16765095 STM0272 (ClpV) promotor (↑); STM0279 (hcp) promotor (↑); STM0285 promotor (↑); STM0289 (VgrG) promotor (↑); STM0268 promotor (↑)
REG0088 experimental T6SS0023 experimental protein Global regulator Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 STM0693 (Fur) NC_003197 756397..756849 (-) 16764063 STM0272 (ClpV) promoter (↑)
REG0089 experimental T6SS0028 insolico protein Unknown Xanthomonas axonopodis pv. citri str. 306 xac4129 (ecfK/RpoE,ECF σ factor) NC_003919 4850278..4850805 (+) 489582896 Unknown (↓)
REG0090 experimental T6SS0028 insolico protein Unknown Xanthomonas axonopodis pv. citri str. 306 xac4127 (PknS) NC_003919 4846892..4849411 (+) 505284326 Unknown (↓)
REG0091 experimental T6SS0035 experimental protein TCS-RR Pseudomonas protegens Pf-5 PFL_RS17995 (gacA/uvrY/SirA) NC_004129 4110513..4111154 (-) 499374263 T6SS transcripts (↓)
REG0092 experimental T6SS0035 experimental protein Tpp Pseudomonas protegens Pf-5 PFL_RS30815 (pppA) NC_004129 6902924..6903658 (-) 499376669 Hcp secretion (↑)
REG0093 experimental T6SS0040 experimental protein QS regulatory pathway Pectobacterium atrosepticum SCRI1043 ECA_RS00520 (expI) NC_004547 125689..126339 (+) 499404281 T6SS transcripts (ECA4275[hcp1], ECA3428[hcp2] and ECA2866[hcp3]) (↓)
REG0094 experimental T6SS0040 experimental protein Global regulator Pectobacterium atrosepticum SCRI1043 ECA3435 (bEBP/VasH) NC_004547 3850745..3852298 (-) 499407476 T6SS gene cluster promoter (PECA3445) (↓); Hcp gene cluster promoter (PECA4275) (↓); Hcp gene cluster promoter (PECA2866) (↓)
REG0095 experimental T6SS0040 experimental protein Global regulator Pectobacterium atrosepticum SCRI1043 ECA0288 (rpoN) NC_004547 336007..337440 (-) 499404454 T6SS gene cluster promoter (PECA3445) (↓); Hcp gene cluster promoter (PECA4275) (↓); Hcp gene cluster promoter (PECA2866) (↓)
REG0096 experimental T6SS0041 insolico; T6SS0042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv. tomato str. DC3000 PSPTO_RS08845 (relA) NC_004578 1863879..1866122 (+) 494457621 T6SS transcripts (↓)
REG0097 experimental T6SS0041 insolico; T6SS0042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv. tomato str. DC3000 PSPTO_RS00410 (spoT) NC_004578 94805..96910 (-) 492171753 T6SS transcripts (↓)
REG0098 experimental T6SS0041 insolico; T6SS0042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv. tomato str. DC3000 PSPTO_RS04545 (fpRel) NC_004578 927082..927900 (+) 499415849 T6SS transcripts (↓)
REG0099 experimental T6SS0041 insolico; T6SS0042 experimental protein Global regulator Pseudomonas syringae pv. tomato str. DC3000 PSPTO_RS28060 (Sfa) NC_004578 6165047..6166564 (-) 499418021 T6SS transcripts (↓)
REG0100 experimental T6SS0043 experimental; T6SS0044 experimental protein TCS-HK Vibrio parahaemolyticus RIMD 2210633 VP_RS12495 (barA) NC_004603 2712492..2715290 (+) 491625032 Hcp expression and secretion (↓)
REG0101 experimental T6SS0043 experimental; T6SS0044 experimental protein TCS-RR Vibrio parahaemolyticus RIMD 2210633 VP_RS09470 (UvrY) NC_004603 2037468..2038112 (-) 491529158 CsrB (↓)
REG0102 experimental T6SS0043 experimental; T6SS0044 experimental protein carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP_RS12395 (CsrA) NC_004603 2688313..2688510 (-) 490550575 Hcp and vgrG expression and secretion (↓)
REG0106 experimental T6SS0043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 vp2049 (Thymidylate kinase,Tmk) NC_004603 2150113..2150745 (-) 28898823 T6SS1 (VgrG1) expression and secretion (↓)
REG0107 experimental T6SS0043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP1028 (TfoY) NC_004603 1077946..1078536 (-) 28897802 T6SS1 (VgrG1) expression and secretion (↓)
REG0108 experimental T6SS0043 experimental protein Global regulator Vibrio parahaemolyticus RIMD 2210633 vp1391 NC_004603 1491226..1492857 (-) 28898165 T6SS1 (VgrG1) expression and secretion (↓)
REG0109 experimental T6SS0043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 vp1407 NC_004603 1511565..1512017 (-) 28898181 T6SS1 (VgrG1) expression and secretion (↓)
REG0110 experimental T6SS0043 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP1133 (hns) NC_004603 1189718..1190125 (-) 28897907 VP1028 (TfoY) (↑)
REG0111 experimental T6SS0043 experimental; T6SS0044 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP2762 (AphA) NC_004603 2929909..2930448 (+) 28899536 T6SS1 transcript (↑); T6SS2 (VPA1027-1024, VPA1043-1028,VPA1044-1046) transcripts (↑)
REG0112 experimental T6SS0043 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP2516 (opaR) NC_004603 2653215..2653829 (+) 28899290 vp1407 (↑); VP1388 promotor (↑); VP1400 promotor (↑); VP1409 promotor (↑)
REG0113 experimental T6SS0044 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP2516 (opaR) NC_004605 2653215..2653829 (+) 28899290 T6SS2 (Hcp2) expression and secretion (↓); VPA1027-1024 transcript (↓); VPA1027-1024 transcript (↓); VPA1027-1024 transcript (↓); VPA1043-1028 transcript (↓); VPA1044-1046 transcript (↓)
REG0114 experimental T6SS0043 experimental protein Transcription regulator Vibrio parahaemolyticus RIMD 2210633 VP0820 (ToxR) NC_004603 847892..848770 (-) 28897594 VP1400 promotor (↑); VP1409 promotor (↑)
REG0115 experimental T6SS0044 experimental protein Transcription regulator Vibrio parahaemolyticus RIMD 2210633 VP0350 (CalR/LeuO) NC_004605 344763..345722 (+) 28897124 VPA1027 (hcp2) promotor (↓); VPA1043 (Fha) promotor (↓); VP1133 (H-NS) (↓)
REG0116 experimental T6SS0043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VPA1088 (cdpA) NC_004605 1147728..1150091 (+) 28900943 VP1028 (TfoY) (↑)
REG0117 experimental T6SS0043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VPA0739 (vdcA) NC_004605 772439..773809 (+) 28900594 VP1028 (TfoY) (↓)
REG0118 experimental T6SS0043 experimental protein Global regulator Vibrio parahaemolyticus RIMD 2210633 VP2516 (OpaR) NC_004603 2653215..2653829 (+) 28899290 T6SS1 (↓)
REG0119 experimental T6SS0044 experimental; T6SS0043 experimental protein QS regulatory pathway; c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 VP1241 (TfoX) NC_004603 1309223..1309810 (+) 28898016 T6SS2 (↓); T6SS1 (↓)
REG0120 experimental T6SS0049 insolico protein QS regulatory pathway Chromobacterium violaceum ATCC 12472 CV_RS20220 (CviR) NC_005085 4426186..4427046 (+) 1169634970 CV_RS06990 (VgrG) promotor (↓)
REG0121 experimental T6SS0049 insolico protein QS regulatory pathway Chromobacterium violaceum ATCC 12472 CV_RS23145 (CviI) NC_005085 4426967..4427620 (-) 499450174 CV_RS20220 (CviR) (↓)
REG0122 experimental T6SS0084 experimental protein QS regulatory pathway Vibrio fischeri ES114 VF2177 (LitR) NC_006840 2446537..2447142 (+) 59712784 Unknown (↓)
REG0123 experimental T6SS0084 experimental protein Global regulator Vibrio fischeri ES114 VF0896 (TfoX) NC_006840 986000..986629 (+) 59711503 T6SS transcripts (↓)
REG0124 experimental T6SS1277 experimental protein Global regulator Aliivibrio fischeri strain FQ-A001 VFFQA001_02105 (rpoN) NZ_SJSX01000002 62995..64464 (-) 501526930 hcp1/hcp transcript (↓)
REG0125 experimental T6SS1278 experimental protein Global regulator Aliivibrio fischeri strain FQ-A001 VFFQA001_15620 (VasH) NZ_SJSX01000004 359608..360108 (+) 1027725198 Unknown (↓)
REG0126 experimental T6SS0070 experimental protein Transcription regulator Burkholderia mallei ATCC 23344 BMAA1517 NC_006349 1646532..1647593 (-) 499517952 Hcp1 (BMAA0742) expression (↓)
REG0127 experimental T6SS0070 experimental protein TCS-RR Burkholderia mallei ATCC 23344 BMAA0746 (VirG) NC_006349 764773..765510 (+) 490311617 Hcp1 (BMAA0742) expression (↓)
REG0128 experimental T6SS0070 experimental protein TCS-HK Burkholderia mallei ATCC 23344 BMAA0745 (VirA) NC_006349 762932..764776 (+) 490305845 Hcp1 (BMAA0742) expression (↓)
REG0129 experimental T6SS0070 experimental protein TCS-RR Burkholderia mallei ATCC 23344 BMAA0746 (VirG) NC_006349 764773..765510 (+) 53717366 BMAA0742 (Hcp1) expression (↓); BMAA0729.1 (TssM1) expression (↓)
REG0130 experimental T6SS0070 experimental protein TCS-HK Burkholderia mallei ATCC 23344 BMAA0745 (VirA) NC_006349 763148..764776 (+) 53717365 BMAA0746 (VirG) (↓)
REG0131 experimental T6SS0074 insolico protein Unknown Burkholderia pseudomallei K96243 BPSL3431 (TctR) NC_006350 4073388..4074029 (-) 53721038 T6SS-2 (hcp2) transcript (↑)
REG0132 experimental T6SS0076 insolico; T6SS0077 insolico protein Unknown Burkholderia pseudomallei K96243 BPSL2246 (PpiB) NC_006350 2708622..2709113 (+) 53719855 T6SS-3 (BPSS2099/TssCIII and BPSS2098/HcpIII) expression (↑); T6SS-6 (hcp6) transcript (↓)
REG0133 experimental T6SS0077 insolico protein Unknown Burkholderia pseudomallei K96243 BPSS1504 NC_006351 2052905..2055547 (+) 499518990 hcp1 secretion
REG0134 experimental T6SS0077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 BPSS1546 (BsaN) NC_006351 2100565..2101230 (-) 490660320 BPSS1495 (virA) promotor (↓)
REG0135 experimental T6SS0077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 BPS_RS27070 (bicA) NC_006351 2087441..2087956 (-) 490293043 BPSS 1495(virA) (↓)
REG0136 experimental T6SS0077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 BPS_RS27175 (bprP) NC_006351 2105881..2106081 (+) 490293055 BPSS1546 (BsaN) (↓)
REG0137 experimental T6SS0077 insolico protein TCS-RR; BsaN regulon Burkholderia pseudomallei K96243 BPSS1495 (virA) NC_006351 2038711..2040555 (-) 499518988 T6SS-1 transpript (↓)
REG0138 experimental T6SS0077 insolico protein TCS-HK; BsaN regulon Burkholderia pseudomallei K96243 BPSS1494 (virG) NC_006351 2037977..2038714 (-) 490663798 BPSS1495 (virA) (↓)
REG0139 experimental T6SS0077 insolico protein bspR-dependent signalling cascade Burkholderia pseudomallei K96243 BPSL1105 (bprP) NC_006350 1275668..1276300 (+) 490290369 tssA expression (↓)
REG0140 experimental - protein bspR-dependent signalling cascade bprp HM447214 175..1146 (+) 298239796 tssA expression (↓)
REG0141 experimental - protein bspR-dependent signalling cascade bsaN - - () tssA expression (↓)
REG0142 experimental - protein bspR-dependent signalling cascade bspR HM358865 258..890 (+) 298239780 tssA expression (↓)
REG0143 experimental - protein bspR-dependent signalling cascade bprc - - () tssA expression (↓)
REG0144 experimental T6SS0077 insolico protein bspR-dependent signalling cascade Burkholderia pseudomallei K96243 BPSS1520 (bprC) NC_006351 2072125..2073186 (-) 499518995 tssA expression (↓)
REG0145 experimental T6SS0077 insolico protein TCS-HK Burkholderia pseudomallei K96243 BPSS1495 (virA) NC_006351 2038711..2040555 (-) 53722517 hcp1 expression (↓)
REG0146 experimental T6SS0077 insolico protein TCS-RR Burkholderia pseudomallei K96243 BPSS1494 (virG) NC_006351 2037977..2038714 (-) 53722516 hcp1 expression (↓)
REG0147 experimental T6SS0081 experimental protein TCS-RR Francisella tularensis subsp. tularensis SCHU S4 FTT1557c/FNU0663.2 (pmrA) NC_006570 1618742..1619428 (-) 489108239 T6SS transcription (↓)
REG0148 experimental T6SS0086 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv. syringae B728a PSYR_RS19090 (relA) NC_007005 4380642..4382885 (-) 499587809 T6SS transcripts (↓)
REG0149 experimental T6SS0086 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv. syringae B728a PSYR_RS01070 (spoT) NC_007005 223004..225109 (-) 489499092 T6SS transcripts (↓)
REG0150 experimental T6SS0086 experimental protein TCS-HK Pseudomonas syringae pv. syringae B728a Psyr_3698 (gacS) NC_007005 4385550..4388303 (+) 499587812 T6SS transcription (↓)
REG0151 experimental T6SS0086 experimental protein QS regulatory pathway Pseudomonas syringae pv. syringae B728a Psyr_4339 (ladS) NC_007005 5191591..5193585 (-) 639463044 T6SS transcription (↓)
REG0152 experimental T6SS0086 experimental protein QS regulatory pathway Pseudomonas syringae pv. syringae B728a Psyr_4408 (retS) NC_007005 5270882..5273671 (+) 489494774 T6SS transcription (↑)
REG0153 experimental T6SS0113 experimental protein Global regulator Burkholderia thailandensis E264 BTH_I1281 (OxyR) NC_007651 1432632..1433591 (+) 497575020 BTH_RS09735 (T6SS-4) Promotor,−536 to −186 relative to the ATG start codon (↑)
REG0154 experimental T6SS0113 experimental protein Global regulator Burkholderia thailandensis E264 bth_I0691 (Zur) NC_007651 796074..796538 (-) 497578547 BTH_RS09735 (T6SS-4) Promotor,−541 to −1 relative to the ATG start codon (↑)
REG0155 experimental T6SS0115 experimental protein QS regulatory pathway Burkholderia thailandensis E264 BTH_II1510 (BtaR1) NC_007650 1779070..1779789 (-) 497583165 BTH_I2691/BTH_I2693-99/BTH_I2701-702 (↓)
REG0156 experimental T6SS0125 insolico protein other regulator Pseudomonas entomophila L48 pvfC NC_008027 - () T6SS secreted proteome (↓)
REG0157 experimental T6SS0150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 rmsF NZ_JARI00000000 - (-) tssA1 RNA (↑); RsmY/Z (↑)
REG0158 experimental T6SS0150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_52570 (RsmA) NC_008463 4660393..4660578 (-) 489176459 RSMF (↑); tssA1 RNA (↑); RSMA (↑)
REG0159 experimental T6SS0150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_RS20260/PA1120 (YfiN/TpbB) NC_008463 4435431..4436738 (-) 489207392 Hcp1 production (↓)
REG0160 experimental T6SS0150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_RS15060 (PA2133 phosphodiesterase) NC_008463 3294000..3294857 (-) 489200657 Hcp1 production (↑)
REG0161 experimental T6SS0150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_RS06615 (WspR) NC_008463 1413158..1414201 (+) 489183089 Hcp1 production (↓)
REG0164 experimental T6SS0150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_RS05020 (LadS) NC_008463 1069280..1071716 (+) 15599169 Unknown
REG0165 experimental T6SS0150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_64230/PA4856 (RetS) NC_008463 5722815..5725643 (+) 489202068 Unknown
REG0166 experimental T6SS0152 experimental; T6SS0151 experimental; T6SS0150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_45960 (lasR) NC_008463 4085339..4086058 (-) 489173455 TssA2 (PA14_43050) promotor (↓); HSI-III transcripts (↓); HSI-I transcripts (↑)
REG0167 experimental T6SS0152 experimental; T6SS0151 experimental; T6SS0150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_51340 (MvfR) NC_008463 4562837..4563835 (+) 489176730 Upstream of pqs operon (↓); HSI-III transcripts (↓); HSI-I transcripts (↑)
REG0168 experimental T6SS0150 experimental; T6SS0152 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_51380 (pqsE) NC_008463 4566077..4566982 (+) 489176725 T6SS Transciption (↓)
REG0169 experimental T6SS0150 experimental; T6SS0152 experimental; T6SS0151 experimental protein Global regulator Pseudomonas aeruginosa UCBPP-PA14 PA14_22470 (PA3225) NC_008463 1955624..1956553 (-) 489182081 PA14_00990 (TssA) promotor (↓); TssA1 (PA14_00990) transcript (↑); TssA2 (PA14_43050) transcript (↑); TssB3 (PA14_34070) transcript (↑)
REG0170 experimental T6SS0150 experimental; T6SS0152 experimental; T6SS0151 experimental protein Global regulator Pseudomonas aeruginosa UCBPP-PA14 PA14_20290 (AmrZ) NC_008463 1747602..1747928 (-) 489182353 TssA1 (PA14_00990) promotor (↓); TssA2 (PA14_43050) promotor (↑); TssB3 (PA14_34070) promotor (↓)
REG0171 experimental T6SS0155 insolico protein Global regulator Escherichia coli APEC O1 APECO1_487 (FNR) NC_008563 1455411..1456163 (-) 446534565 APECO1_1756 (VgrG1) (↓)
REG0172 experimental T6SS0152 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 PA14_48150 (QslA) NC_008463 4286195..4286536 (-) 489210784 H2-T6SS (PA14_43050) promotor (↑)
REG0173 experimental T6SS0158 experimental protein TCS regulatory pathway Francisella novicida U112 FTN_RS06610 (mglA) NC_008601 1362282..1362899 (+) 489124662 iglC transcription (↓); Unknown (↓)
REG0174 experimental T6SS0158 experimental protein TCS regulatory pathway Francisella novicida U112 FTN_RS02845 (SspA) NC_008601 574840..575472 (+) 500053699 FTN_1465 (pmrA) (↓)
REG0175 experimental T6SS0158 experimental protein TCS-HK Francisella novicida U112 FTN_RS08805 (KdpD) NC_008601 1838601..1841282 (-) 489131611 FTN_1465 (pmrA) (↓)
REG0176 experimental T6SS0158 experimental protein TCS-RR; TCS regulatory pathway Francisella novicida U112 FTN_1465 (pmrA) NC_008601 1553358..1554044 (-) 489108239 FTN_1465 (pmrA) promotor (↓); pdpD promotor (↓); IglA expression (↓)
REG0177 experimental T6SS0158 experimental protein Global regulator; TCS regulatory pathway Francisella novicida U112 FTN_RS06615 (mglB) NC_008601 1362901..1363308 (+) 489112095 IglA expression (↓); T6SS Transciption (↓)
REG0178 experimental T6SS0158 experimental protein TCS regulatory pathway Francisella novicida U112 FTN_0480 (fevR/PigR) NC_008601 486541..486876 (+) 489108070 T6SS Transciption (↓)
REG0179 experimental T6SS1000 insolico protein Global regulator Acinetobacter baumannii ATCC 17978 A1S_0268 (hns) CP000521 292215..292541 (+) A1S_1292 Transcript (↑)
REG0180 experimental T6SS0208 insolico; T6SS0487 insolico protein Global regulator Vibrio cholerae O395 VC0395_RS17530 (TsrA) NC_009457 2598392..2598676 (+) 445982516 T6SS Transciption (↑)
REG0181 experimental T6SS0208 insolico protein Global regulator Vibrio cholerae O395 VC0395_0020/VCA0117 (bEBP/vasH) NC_009456 22315..23907 (-) 446006938 T6SS gene cluster promoter (PVCA0107/VC0395_RS00160) (↓)
REG0182 experimental T6SS0208 insolico protein Global regulator Vibrio cholerae O395 VC0395_A2109 (rpoN) NC_009457 2265078..2266541 (+) 446727517 T6SS gene cluster promoter (PVCA0107/VC0395_RS00160) (↓); hcp promoter (PVCA0017/VC0395_0116) (↓)
REG0183 experimental T6SS0216 insolico protein Global regulator Marinomonas sp. MWYL1 Mmwyl1_1758 (bEBP/vasH) NC_009654 1985170..1986666 (+) 501016781 T6SS gene cluster promoter (PMWYL1196/PMWYL1195) (↓)
REG0184 experimental T6SS0216 insolico protein Global regulator Marinomonas sp. MWYL1 Mmwyl1_2418 (RpoN) NC_009654 2725212..2726687 (+) 501017436 T6SS gene cluster promoter (PMWYL1196/PMWYL1195) (↓)
REG0185 experimental T6SS0225 experimental protein TCS-RR Yersinia pseudotuberculosis IP 31758 YpsIP31758_3980 (ompR) NC_009708 4465260..4465979 (-) 490527984 T6SS-4 promoter (↓)
REG0186 experimental T6SS0225 experimental protein Unknown Yersinia pseudotuberculosis IP 31758 YpsIP31758_3441 (lptD) NC_009708 3878499..3880841 (+) 499505072 YpsIP31758_3980 (ompR) (↓)
REG0187 experimental T6SS0260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII YPK_3449 (RelA) NC_010465 3783755..3785989 (-) 488138165 YPK_1551 (RovM) (↓); YPK_1876 (RovA) (↓)
REG0188 experimental T6SS0260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII YPK_1876 (RovA) NC_010465 2082384..2082815 (+) 488139747 T6SS-4 promoter region (↓); T6SS-4 promoter region (↓)
REG0189 experimental T6SS0260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII YPK_4079 (OxyR) NC_010465 4502978..4503895 (-) 488138270 T6SS-4 promoter region (↓)
REG0190 experimental T6SS0260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII ypk_3425 (RpoS) NC_010465 3759239..3760237 (-) 499505140 T6SS-4 promoter region (↓)
REG0191 experimental T6SS0260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII YPK_1551 (RovM) NC_010465 1713682..1714884 (-) 499506038 T6SS-4 promoter region (↓)
REG0192 experimental T6SS0260 experimental protein carbon storage regulatory pathway Yersinia pseudotuberculosis YPIII YPK_3567 (RovC) NC_010465 3929654..3930397 (+) 170025782 YPK_3567 promotor (↓)
REG0193 experimental T6SS0260 experimental protein carbon storage regulatory pathway Yersinia pseudotuberculosis YPIII YPK_3372 (CsrA) NC_010465 3698608..3698793 (-) 169752121 YPK_3567 (RovC) (↑); YPK_3563 transcript (↑)
REG0194 experimental T6SS0260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII YPK_2462 (HpaR) NC_010465 2695107..2695574 (+) 169751221 T6SS4 promoter (↓)
REG0195 experimental T6SS0256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII YPK_RS08345 (YpsR) NC_010465 1837676..1838413 (+) 488140651 T6SS transcripts (↓)
REG0196 experimental T6SS0256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII YPK_RS03965 (YtbR) NC_010465 900476..901219 (+) 488140447 T6SS transcripts (↓)
REG0197 experimental T6SS0256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII YPK_RS08350 (ypsI) NC_010465 1838406..1839050 (-) 501053391 T6SS transcripts (↓)
REG0198 experimental T6SS0256 insolico; T6SS0260 experimental protein QS regulatory pathway Yersinia pseudotuberculosis YPIII YPK_RS03970 (ytbI) NC_010465 901200..901850 (-) 488144695 T6SS transcripts (↓); T6SS4 transcripts and hcp secretion (↓)
REG0199 experimental T6SS0260 experimental protein TCS-RR Yersinia pseudotuberculosis YPIII YPK_RS00840 (OmpR) NC_010465 223260..223979 (+) 488137706 T6SS4 promoter (↓)
REG0200 experimental T6SS0260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII YPK_RS01520 (ZntR) NC_010465 333471..333896 (+) 488144494 T6SS4 promoter (↓)
REG0201 experimental T6SS0272 experimental protein Global regulator Proteus mirabilis HI4320 PMI0271 (MrpJ) NC_010554 318458..318781 (+) 490365253 PMI0749 (tssA); PMI2990 (idsA/hcp)
REG0202 experimental T6SS0287 experimental protein Unknown Xanthomonas oryzae pv. oryzae PXO99A PXO_RS20535 NC_010717 4488457..4488843 (-) 499576999 Unknown (↓)
REG0203 experimental T6SS0344 experimental protein Global regulator Klebsiella pneumoniae NTUH-K2044 KP1_3314 (hns) NC_012731 3140175..3140582 (+) 238895262 KP1_2392 (TssB) promotor (↑); KP1_2392 (hcp) (↑)
REG0204 experimental T6SS0346 experimental protein TCS-RR Edwardsiella ictaluri 93-146 NT01EI_RS04325 (EsrB) NC_012779 955101..955745 (-) 506350644 T6SS translocon protein EvpC secretion (↓)
REG0205 experimental T6SS0346 experimental protein TCS regulatory pathway Edwardsiella ictaluri 93-146 NT01EI_RS04200 (EsrC) NC_012779 933326..934018 (-) 737638726 T6SS translocon protein EvpC secretion (↓)
REG0206 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2873 (RpoS) NC_013508 3025094..3026080 (-) 502612732 ETAE_0886 (esrB) promoter (↑)
REG0207 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0035 NC_013508 35881..37008 (-) 502609898 ETAE_0886 (esrB) promoter (↑)
REG0208 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0154 (hemB) NC_013508 159867..160889 (+) 502610017 ETAE_0886 (esrB) promoter (↑)
REG0209 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0743 (cdsA) NC_013508 820052..820909 (+) 502610607 ETAE_0886 (esrB) promoter (↑)
REG0210 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2082 (pyrF) NC_013508 2196136..2196858 (-) 502611934 ETAE_0886 (esrB) promoter (↑)
REG0211 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1096 (dapA) NC_013508 1194778..1195659 (+) 502610962 ETAE_0886 (esrB) promoter (↑)
REG0212 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2697 (cysS) NC_013508 2831230..2832615 (-) 502612557 ETAE_0886 (esrB) promoter (↑)
REG0213 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1760 CP001135 1870377..1870535 (+) 267984768 ETAE_0886 (esrB) promoter (↑)
REG0214 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1837 CP001135 1946159..1946284 (-) 267984845 ETAE_0886 (esrB) promoter (↑)
REG0215 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1202 (ugd) NC_013508 1306603..1307769 (+) 502611067 ETAE_0886 (esrB) promoter (↑)
REG0216 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2640 (holA) NC_013508 2779832..2780866 (+) 502612494 ETAE_0886 (esrB) promoter (↑)
REG0217 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1439 (ruvA) NC_013508 1550776..1551384 (+) 502611302 ETAE_0886 (esrB) promoter (↑)
REG0218 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0358 (purA) NC_013508 403538..404836 (+) 502610221 ETAE_0886 (esrB) promoter (↑)
REG0219 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2813 (iscA) NC_013508 2952011..2952334 (-) 491431780 ETAE_0886 (esrB) promoter (↑)
REG0220 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2787 (guaB) NC_013508 2925310..2926776 (-) 502612646 ETAE_0886 (esrB) promoter (↑)
REG0221 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1412 NC_013508 1522924..1523409 (-) 502611274 ETAE_0886 (esrB) promoter (↑)
REG0222 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0430 NC_013508 473075..473755 (-) 502610291 ETAE_0886 (esrB) promoter (↑)
REG0223 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0659 (aceE) NC_013508 731608..734271 (+) 502610523 ETAE_0886 (esrB) promoter (↑)
REG0224 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2773 (mtnN) NC_013508 2910743..2911441 (+) 502612632 ETAE_0886 (esrB) promoter (↑)
REG0225 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2468 NC_013508 2598484..2599356 (-) 504339400 ETAE_0886 (esrB) promoter (↑)
REG0226 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1614 NC_013508 1721332..1722024 (-) 754045576 ETAE_0886 (esrB) promoter (↑)
REG0227 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0994 (Lon) NC_013508 1085063..1087288 (+) 267984010 ETAE_0886 (esrB) promoter (↓)
REG0228 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_3542 (phoU) NC_013508 3747537..3748268 (+) 502613380 ETAE_0886 (esrB) promoter (↓)
REG0229 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_3449 (tpiA) NC_013508 3637381..3638145 (+) 502613286 ETAE_0886 (esrB) promoter (↓)
REG0230 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1655 (prc) NC_013508 1757898..1759940 (+) 735677771 ETAE_0886 (esrB) promoter (↓)
REG0231 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1158 NC_013508 1257412..1258584 (+) 502611022 ETAE_0886 (esrB) promoter (↓)
REG0232 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0772 (tadA) NC_013508 850367..850879 (+) 505698653 ETAE_0886 (esrB) promoter (↓)
REG0233 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0695 (mrcB) NC_013508 766885..769368 (+) 502610560 ETAE_0886 (esrB) promoter (↓)
REG0234 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1170 CP001135 1271304..1271447 (-) 267984186 ETAE_0886 (esrB) promoter (↓)
REG0235 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1562 NC_013508 1668753..1670378 (-) 780104675 ETAE_0886 (esrB) promoter (↓)
REG0236 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_3453 (cpxR) NC_013508 3641204..3641902 (+) 502613290 ETAE_0886 (esrB) promoter (↓)
REG0237 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0263 (mltC) NC_013508 293215..294306 (-) 1392602598 ETAE_0886 (esrB) promoter (↓)
REG0238 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_0542 (slt) NC_013508 588958..590886 (+) 502610404 ETAE_0886 (esrB) promoter (↓)
REG0239 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_2638 (leuS) NC_013508 2776570..2779152 (+) 502612492 ETAE_0886 (esrB) promoter (↓)
REG0240 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_3207 (rplQ) NC_013508 3390207..3390593 (-) 491439763 ETAE_0886 (esrB) promoter (↓)
REG0241 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1010 (acrB) NC_013508 1099309..1102461 (-) 502610875 ETAE_0886 (esrB) promoter (↓)
REG0242 experimental T6SS0372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 ETAE_1425 (mviN) NC_013508 1535368..1536906 (+) 502611288 ETAE_0886 (esrB) promoter (↓)
REG0243 experimental T6SS0372 experimental protein TCS-RR Edwardsiella tarda EIB202 ETAE_0886 (EsrB) NC_013508 964658..965302 (-) 502610749 Unknown (↓); Unknown (↓)
REG0244 experimental T6SS0372 experimental protein TCS-HK Edwardsiella tarda EIB202 ETAE_2059 (phoP) NC_013508 2172565..2173239 (+) 502611910 ETAE_0886 (EsrB) (↓)
REG0245 experimental T6SS0372 experimental protein Transcription regulator Edwardsiella tarda EIB202 ETAE_3098 (PepA) NC_013508 3260322..3261833 (+) 502612947 ETAE_0886 (esrB) promoter (↑)
REG0246 experimental T6SS0372 experimental protein QS regulatory pathway Edwardsiella tarda EIB202 ETAE_3474 (fabR) NC_013508 3666488..3667159 (-) 502613311 Unknown (↓)
REG0247 experimental T6SS0372 experimental protein Transcription regulator Edwardsiella tarda EIB202 ETAE_1505 (H-NS) NC_013508 1615099..1615506 (-) 505274277 ETAE_2430 (evpB) (↑); evpC promotor (↑)
REG0248 experimental T6SS0464 experimental protein Transcription regulator Escherichia coli 042 EC042_RS26480 (aggR) NC_017627 41080..41877 (-) 446692110 EC042_RS26480 (aggR) promoter (↓); EC042_RS26480 (aggR) promoter (↓)
REG0249 experimental T6SS0464 experimental protein Transcription regulator Escherichia coli 042 EC042_RS18855 (FIS) NC_017626 3772795..3773091 (+) 446385050 EC042_RS26480 (aggR) promoter (↓)
REG0250 experimental T6SS0464 experimental protein Global regulator Escherichia coli 042 EC042_RS06800 (Hns) NC_017626 1376831..1377244 (-) 447210122 EC042_RS26480 (aggR) promoter (↑)
REG0251 experimental T6SS0464 experimental protein Global regulator Escherichia coli 042 EC042_RS03685 (Fur) NC_017626 786918..787364 (-) 446053847 EC042_4532 promoter (↑); EC042_4524 (TssB) promotor (↑)
REG0252 experimental T6SS0464 experimental protein Global regulator Escherichia coli 042 EC042_RS19435 (Dam) NC_017626 3861171..3862007 (-) 446664793 EC042_4532 promoter (↑)
REG0253 experimental T6SS0612 insolico; T6SS0613 insolico; T6SS0611 insolico protein TCS-RR Pseudomonas aeruginosa M18 PAM18_RS12360 (gacA) NC_017548 2625815..2626459 (+) 489180874 hsiA1 operon transcript (↓); hsiA2 operon transcript (↓); hsiA3 operon transcript (↓)
REG0254 experimental T6SS0788 experimental protein Transcription regulator Aeromonas hydrophila SSU VasH DQ667172 15458..16996 (+) 110277136 hcp expression (↓)
REG0255 experimental T6SS0788 experimental protein QS regulatory pathway Aeromonas hydrophila SSU ahyI DQ398101 843..1466 (+) 89027174 ahyR (↓)
REG0256 experimental T6SS0788 experimental protein QS regulatory pathway Aeromonas hydrophila SSU ahyR DQ398101 1..783 (-) 89027173 hcp and vgrG2 expression (↓)
REG0257 experimental T6SS0794 experimental protein Tpp Vibrio alginolyticus EPJS VEPGS_0614 (PppA) FJ790777 15765..16880 (+) 225382180 LuxR (↓)
REG0258 experimental T6SS0794 experimental protein Tpp Vibrio alginolyticus EPJS VEPGS_0606 (PpkA2) FJ790777 3227..5377 (-) 225382172 LuxR (↓); VEPGS_0610 (DotU2) (↓)
REG0259 experimental T6SS0794 experimental protein Tpp Vibrio alginolyticus EPJS VEPGS_0607 (Fha2) FJ790777 5690..6775 (+) 225382173 VEPGS_0610 (DotU2) (↓)
REG0260 experimental T6SS0794 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS EPGS_00471 (VtsR) FJ790777 - () LuxO (↓)
REG0261 experimental T6SS0793 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS EPGS_00471 (VtsR) FJ790776 - () LuxO (↑)
REG0262 experimental T6SS0794 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS luxR FJ790777 - () T6SS2 transcript and expression (↓)
REG0263 experimental T6SS0793 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS luxR FJ790776 - () T6SS1 transcript and expression (↑)
REG0264 experimental T6SS0793 experimental protein Tpp; QS regulatory pathway Vibrio alginolyticus EPJS VEPGS_0621 (pppA) FJ790776 23577..24245 (+) 225382187 Unknown (↑); T6SS1 transcript (↑); hcp1 transcript (↓)
REG0265 experimental T6SS0793 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS luxS FJ790776 - () hcp1 transcript (↓)
REG0266 experimental T6SS0793 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS LuxO FJ790776 - () hcp1 transcript (↓)
REG0267 experimental T6SS0794 experimental protein QS regulatory pathway Vibrio alginolyticus EPJS LuxO FJ790777 - () Unknown (↑)
REG0268 experimental T6SS0793 experimental protein Transcription regulator Vibrio alginolyticus EPJS rpoN FJ790776 - () T6SS1 transcript (↓)
REG0269 experimental T6SS0793 experimental protein Transcription regulator Vibrio alginolyticus EPJS VasH FJ790776 - () T6SS1 transcript (↓)
REG0270 experimental T6SS0904 experimental protein Transcription regulator Escherichia coli strain TW-XM CXG97_03740 (Fur) NZ_CP025328 729474..729920 (-) 446053847 T6SS1 (TssB) promotor (↑)
REG0271 experimental T6SS0931 experimental protein Global regulator Escherichia coli 17-2 H1D38_08255 (fur) JACEFV010000001 1744748..1745194 (-) MBA2233871.1 sciH promotor (↑)
REG0272 experimental T6SS0931 experimental protein Global regulator Escherichia coli 17-2 H1D38_12840 (Dam) JACEFV010000002 105877..106713 (+) MBA2234741.1 sciH promotor (↑)
REG0273 experimental T6SS0937 experimental protein TCS-RR Escherichia coli DE719 W817_21870 (CpxR) NZ_CP007149 4360812..4361510 (-) 446956464 hcp2B promoter (↓)
REG0274 experimental T6SS0937 experimental protein TCS Escherichia coli DE719 W817_01610 (NplE) NZ_CP007149 214947..215657 (+) 446161331 W817_RS21690 (CpxA) (↓)
REG0275 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_21538 (LuxR) AAPS01000053 13551..14165 (-) 91187814 T6SS2 transcripts (↓)
REG0276 experimental T6SS0939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 V12G01_19736 (TfoX) AAPS01000019 47689..48276 (-) 91189146 T6SS2 transcripts (↓)
REG0277 experimental T6SS0939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 V12G01_20658 (TfoY) AAPS01000015 63783..64190 (+) 91189474 T6SS transcripts (↓)
REG0278 experimental T6SS0939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 V12G01_20201 (H-NS) AAPS01000015 63783..64190 (+) 91189474 VaT6SS1 transcripts (↑)
REG0279 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01-18672 (vqsA) AAPS01000003 114208..115086 (+) 91191289 V12G01-21538 (luxR) promoter (↓); V12G01-14830 (aphA) promoter (↓); V12G01-18672 (vqsA) promotor (↓)
REG0280 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_10813 (AsnC) AAPS01000004 181050..181484 (-) 91191052 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0281 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_02325 (HP) AAPS01000004 115263..116411 (+) 91190993 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0282 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_01665 (HP) AAPS01000007 185299..185712 (+) 91190406 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0283 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_06711 (HP) AAPS01000024 47707..48585 (-) 91188835 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0284 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_16177 (MetR) AAPS01000023 58420..59331 (-) 91188901 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0285 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_02620 (SoxR) AAPS01000004 181050..181484 (-) 91191052 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0286 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01_21538 (luxR) AAPS01000053 13551..14165 (-) 91187814 V12G01-18672 (vqsA) promotor
REG0287 experimental T6SS0939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 V12G01-14830 (aphA) AAPS01000027 42305..42880 (+) 91188695 V12G01-18672 (vqsA) promotor
REG0288 experimental T6SS0002 experimental protein TCS-RR Vibrio cholerae O1 biovar El Tor str. N16961 VCA1552_03277/VCA0566 (VxrB) NC_002506 504728..505384 (+) 446737785 Unknown (↑)
REG0289 experimental T6SS0002 experimental protein c-di-GMP regulatory pathway Vibrio cholerae O1 biovar El Tor str. N16961 VCA0933 (CspV) NC_002506 886068..886280 (+) 446027150 Unknown (↓)
REG0290 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_01380 (VdcA/ycdT) NZ_CP024867 1482426..1483715 (+) 446892247 the levels of c-di-GMP (↑)
REG0291 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_02536 (CdpA/YfgF) NZ_CP024867 2739669..2742158 (-) 446417730 the levels of c-di-GMP (↓)
REG0292 experimental T6SS1112 experimental protein Global regulator Vibrio cholerae A1552 VCA1552_02898 (VasH) NZ_CP024868 128889..130481 (+) 446006938 VCA1552_00900 (TfoX) (↓)
REG0293 experimental T6SS1112 experimental protein Global regulator Vibrio cholerae A1552 VCA1552_00351 (HapR) NZ_CP024867 340447..341058 (-) 446262243 Unknown; Hcp expression and secretion
REG0294 experimental T6SS1112 experimental protein Transcription regulator Vibrio cholerae A1552 VCA1552_RS04890 (ihfA) NZ_CP024867 1028170..1028466 (+) 447152004 Hcp secretion (↓)
REG0295 experimental T6SS1112 experimental protein Transcription regulator Vibrio cholerae A1552 VCA1552_RS08565 (ihfB) NZ_CP024867 1839353..1839631 (-) 446089486 Hcp secretion (↓)
REG0296 experimental T6SS1112 experimental protein QS regulatory pathway Vibrio cholerae A1552 VCA1552_RS03895 (LuxO) NZ_CP024867 818142..819509 (+) 487814784 Hcp expression and secretion (↑)
REG0297 experimental T6SS1112 experimental protein QS regulatory pathway Vibrio cholerae A1552 VCA1552_RS17020 (cqsa) NZ_CP024868 455238..456407 (-) 446962656 Hcp expression and secretion (↓)
REG0298 experimental T6SS1112 experimental protein QS regulatory pathway Vibrio cholerae A1552 VCA1552_RS01665 (LuxS) NZ_CP024867 319588..320106 (+) 447052971 Hcp expression and secretion (↓)
REG0299 experimental T6SS1112 experimental protein QS regulatory pathway Vibrio cholerae A1552 VCA1552_RS00505 (hfq) NZ_CP024867 92673..92936 (+) 446974616 VCA1552_00351 (HapR) (↑)
REG0300 experimental T6SS1112 experimental protein Global regulator Vibrio cholerae A1552 VCA1552_RS11610 (RpoN) NZ_CP024867 2488023..2489486 (+) 446727517 Hcp expression and secretion (↓)
REG0301 experimental T6SS1112 experimental protein QS regulatory pathway Vibrio cholerae A1552 VCA1552_RS12025 (crp) NZ_CP024867 2558371..2559003 (+) 446164894 Hcp expression and secretion (↓)
REG0302 experimental T6SS1112 experimental protein QS regulatory pathway; cAMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS12925 (cya) NZ_CP024867 2747346..2749877 (-) 447072406 VCA1552_RS12025 (crp) (↓)
REG0303 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway; QS regulatory pathway; Global regulator Vibrio cholerae A1552 VC0396/VCA1552_00154 (QstR) NZ_CP024867 149920..150564 (-) 447111060 TssB/ TfoY transcripts (↓); VC0396/VCA1552_00154 (QstR) (↓); T6SS transcripts (↓)
REG0304 experimental T6SS1112 experimental protein Global regulator Vibrio cholerae A1552 VCA1552_00900 (TfoX) NZ_CP024867 952868..953476 (+) 487807468 VC0396/VCA1552_00154 (QstR) (↓)
REG0305 experimental T6SS1112 experimental protein QS regulatory pathway; c-di-GMP regulatory pathway; Global regulator Vibrio cholerae A1552 VCA1552_00154 (QstR) NZ_CP024867 149920..150564 (-) 447111060 Unknown (↓)
REG0306 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_01510 (TfoY) NZ_CP024867 1636980..1637567 (+) 446282733 Unknown (↓)
REG0307 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS06160 (lonA) NZ_CP024867 1315238..1316887 (+) 446116573 VCA1552_01510 (TfoY) (↑)
REG0308 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS10420 (cdgL) NZ_CP024867 2215844..2217361 (-) 446975354 the levels of c-di-GMP (↓)
REG0309 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS04310 (cdgK) NZ_CP024867 901594..903063 (+) 487807420 the levels of c-di-GMP (↓)
REG0310 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS04130 (cdgH) NZ_CP024867 861187..863208 (+) 446848493 the levels of c-di-GMP (↓)
REG0311 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS02130 (rocS) NZ_CP024867 425233..427287 (-) 447034155 the levels of c-di-GMP (↑)
REG0312 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS12850 (cdgJ) NZ_CP024867 2733319..2734545 (-) 446210986 the levels of c-di-GMP (↑)
REG0313 experimental T6SS1112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae A1552 VCA1552_RS17835 (cdgD)