I. Summary
SecReT6 ID111 insolico
StrainBurkholderia thailandensis E264
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BTH_II0115132907..133461 [+], 55583717319frimbrial protein 
2BTH_II0116133543..134268 [+], 72683717851fimbrial chaperone protein ecpD 
3BTH_II0117134305..137124 [+], 282083716782outer membrane usher protein 
4BTH_II0118137144..137689 [+], 54683716399major fimbrial subunit protein 
5BTH_II0119137720..138409 [+], 69083717840hypothetical protein  TssL
6BTH_II0120138412..140088 [+], 167783717470hypothetical protein  TagL
7BTH_II0121140432..140971 [+], 54083716514hypothetical protein  TssB
8BTH_II0122141005..142504 [+], 150083716153hypothetical protein  TssC
9BTH_II0123142705..143187 [+], 48383717589hypothetical protein  TssD
10BTH_II0124143315..143857 [+], 54383717629lipoprotein  TssJ
11BTH_II0125143770..145212 [+], 144383717986hypothetical protein  TssK
12BTH_II0126145209..146510 [+], 130283716132hypothetical protein  TssL
13BTH_II0127146525..150433 [+], 390983716562lipoprotein  TssM
14BTH_II0128150603..151172 [+], 57083717749hypothetical protein 
15BTH_II0129151273..153891 [+], 261983718246Rhs element Vgr protein  TssI
16BTH_II0130153966..154235 [+], 27083716387Rhs family protein  PAAR
17BTH_II0131154248..157700 [+], 345383716726Rhs1 protein 
18BTH_II0132157593..158975 [-], 138383716926hypothetical protein 
19BTH_II0133158984..160117 [-], 113483717748fimbrial protein subfamily protein 
20BTH_II0134160068..161138 [-], 107183716195ImpA-like N-terminal family protein  TssA
21BTH_II0135161157..162206 [-], 105083716825hypothetical protein  TssG
22BTH_II0136162203..164083 [-], 188183718132hypothetical protein  TssF
23BTH_II0137164085..164603 [-], 51983718123hypothetical protein  TssE
24BTH_II0138164590..165444 [-], 85583716566ImpE protein superfamily protein  TagJ
25BTH_II0139165428..166483 [-], 105683717118hypothetical protein 
26BTH_II0140166857..169613 [+], 275783717355ClpA/B type protease  TssH
27BTH_II0141170006..172864 [-], 285983717305two-component system sensor protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Russell AB et al. (2012). A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe. 11(5):538-49. [PudMed:22607806] experimental in_silico
(2) Schwarz S et al. (2010). Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog. 6(8):e1001068. [PudMed:20865170] experimental
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation