I. Summary
SecReT6 ID111 insolico
StrainBurkholderia thailandensis E264
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BTH_RS00590132907..133461 [+], 555499720066type 1 fimbrial protein 
2BTH_RS00595133543..134268 [+], 726499720067fimbria/pilus periplasmic chaperone 
3BTH_RS34170134317..134475 [-], 1591807074601hypothetical protein 
4BTH_RS00600134428..137124 [+], 2697497580537fimbrial biogenesis outer membrane usher protein 
5BTH_RS00605137117..137689 [+], 573648185552type 1 fimbrial protein 
6BTH_RS00610137720..138409 [+], 690497592905DotU family type IV/VI secretion system protein  TssL
7BTH_RS00615138412..140088 [+], 1677497580543OmpA family protein  TagL
8BTH_RS00620 (tssB)140432..140971 [+], 540497580544type VI secretion system contractile sheath small subunit  TssB
9BTH_RS00625 (tssC)141005..142504 [+], 1500497580545type VI secretion system contractile sheath large subunit  TssC
10BTH_RS00630142705..143187 [+], 483497580546type VI secretion system tube protein Hcp  TssD
11BTH_RS00635 (tssJ)143315..143857 [+], 543499720069type VI secretion system lipoprotein TssJ  TssJ
12BTH_RS00640 (tssK)143863..145212 [+], 1350497580548type VI secretion system baseplate subunit TssK 
13BTH_RS00645 (tssL)145209..146510 [+], 1302497580549type VI secretion system protein TssL, long form  TssL
14BTH_RS00650 (tssM)146525..150433 [+], 3909497580552type VI secretion system membrane subunit TssM  TssM
15BTH_RS00655150603..151172 [+], 570497580554hypothetical protein 
16BTH_RS00660 (tssI)151273..153891 [+], 2619499720071type VI secretion system tip protein VgrG  TssI
17BTH_RS00665153966..154235 [+], 270490658703PAAR domain-containing protein  PAAR
18BTH_RS00670154248..157700 [+], 3453499720072RHS repeat protein 
19BTH_RS00675157593..158951 [-], 1359740922510hypothetical protein 
20BTH_RS00680158984..160012 [-], 1029497580566fimbrial protein 
21BTH_RS00685160068..161138 [-], 1071497580567type VI secretion system ImpA family N-terminal domain-containing protein  TssA
22BTH_RS00690 (tssG)161157..162206 [-], 1050497580569type VI secretion system baseplate subunit TssG  TssG
23BTH_RS00695 (tssF)162203..164083 [-], 1881497580571type VI secretion system baseplate subunit TssF  TssF
24BTH_RS00700 (tssE)164085..164603 [-], 519497580573type VI secretion system baseplate subunit TssE  TssE
25BTH_RS00705164590..165396 [-], 807497580574ImpE protein 
26BTH_RS00710165428..166411 [-], 9841844068774TagK domain-containing protein 
27BTH_RS00715 (tssH)166968..169613 [+], 2646497592915type VI secretion system ATPase TssH 
28BTH_RS00720170006..173047 [-], 3042644827693response regulator 
29BTH_RS29330173846..174040 [-], 195497592916hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Russell AB et al. (2012). A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe. 11(5):538-49. [PudMed:22607806] experimental in_silico
(2) Schwarz S et al. (2010). Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog. 6(8):e1001068. [PudMed:20865170] experimental
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation