I. Summary
SecReT6 ID112 insolico
StrainBurkholderia thailandensis E264
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BTH_II0246299015..299911 [-], 89783716438LysR family transcriptional regulator 
2BTH_II0247300115..300819 [+], 70583717769short chain dehydrogenase/reductase oxidoreductase 
3BTH_II0248301071..303068 [+], 199883717274lipoprotein 
4BTH_II0249303044..304426 [-], 138383717306FHA domain-containing protein  Fha
5BTH_II0250304544..304942 [-], 39983717834lipoprotein 
6BTH_II0251305598..306116 [+], 51983716922lipoprotein  TssJ
7BTH_II0252306113..307519 [+], 140783717553hypothetical protein  TssK
8BTH_II0253307535..308848 [+], 131483718191hypothetical protein  TssL
9BTH_II0254308851..312480 [+], 363083716527lipoprotein  TssM
10BTH_II0255312486..313352 [+], 86783716732hypothetical protein 
11BTH_II0256313510..316143 [+], 263483716861serine/threonine protein kinase 
12BTH_II0257316196..317260 [+], 106583717862ImpA-like N-terminal family protein  TssA
13BTH_II0258317322..317903 [+], 58283717683hypothetical protein  TssB
14BTH_II0259317896..319404 [+], 150983717013hypothetical protein  TssC
15BTH_II0260319462..319953 [+], 49283717048hypothetical protein  TssD
16BTH_II0261319972..320532 [+], 56183716379hypothetical protein  TssE
17BTH_II0262320537..322408 [+], 187283717522hypothetical protein  TssF
18BTH_II0263322405..323688 [+], 128483716780hypothetical protein  TssG
19BTH_II0264323701..326358 [+], 265883717896ClpA/B type protease  TssH
20BTH_II0265326364..328559 [+], 219683717324Rhs element Vgr protein  TssI
21BTH_II0266328575..329840 [+], 126683716814hypothetical protein 
22BTH_II0267329863..334482 [+], 462083716862rhsD protein 
23BTH_II0268334616..334726 [-], 11183718106isrso7-transposase 
24BTH_II0269334727..334909 [-], 18383716429transposase 
25BTH_II0270334964..335452 [-], 48983716583transposase 
26BTH_II0271335205..336473 [-], 126983717124transposase mutator family protein 
27BTH_II0272336667..337332 [-], 66683717766HAD-superfamily hydrolase 
28BTH_II0273337540..338127 [-], 58883716564hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Russell AB et al. (2012). A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe. 11(5):538-49. [PudMed:22607806] experimental in_silico
(2) Schwarz S et al. (2010). Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog. 6(8):e1001068. [PudMed:20865170] experimental
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation