I. Summary

SecReT6 ID	114
Strain	Burkholderia thailandensis E264
Replicon	chromosome II [Browse all T6SS(s) in this replicon]
Accession	NC_007650
Location	2282208..2308569
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	2	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	BTH_II1880	2277721..2279148 [-], 1428	83716540	rhamnosyltransferase I subunit B
2	BTH_II1881	2279278..2280177 [-], 900	83716935	rhamnosyltransferase 1 subunit A
3	BTH_II1882	2280750..2281121 [-], 372	83717991	hypothetical protein
4	BTH_II1883	2281342..2281767 [-], 426	83718045	hypothetical protein
5	BTH_II1884	2281790..2282149 [-], 360	83717690	hypothetical protein
6	BTH_II1885	2282208..2285702 [-], 3495	83716717	ImcF-like family protein	TssM
7	BTH_II1886	2285699..2287483 [-], 1785	83717203	hypothetical protein	TssL
8	BTH_II1887	2287509..2288870 [-], 1362	83716495	hypothetical protein	TssK
9	BTH_II1888	2288867..2289346 [-], 480	83718208	lipoprotein	TssJ
10	BTH_II1889	2289466..2289855 [-], 390	83717888	hypothetical protein
11	BTH_II1890	2289895..2290611 [-], 717	83716070	hypothetical protein
12	BTH_II1891	2290614..2291684 [-], 1071	83716702	pentapeptide repeat-containing protein
13	BTH_II1892	2291684..2293834 [-], 2151	83717521	hypothetical protein
14	BTH_II1893	2293904..2296192 [-], 2289	83716389	Rhs element Vgr protein	TssI
15	BTH_II1894	2296361..2298652 [-], 2292	83717067	Rhs element Vgr protein	TssI
16	BTH_II1895	2298643..2301486 [-], 2844	83717751	ATP-dependent Clp protease, ATP-binding subunit ClpB	TssH
17	BTH_II1896	2301489..2302478 [-], 990	83718279	hypothetical protein	TssG
18	BTH_II1897	2302475..2304337 [-], 1863	83716407	hypothetical protein	TssF
19	BTH_II1898	2304351..2304782 [-], 432	83717049	hypothetical protein	TssE
20	BTH_II1899	2304861..2305388 [-], 528	83718015	hypothetical protein	TssD
21	BTH_II1900	2305532..2307037 [-], 1506	83718249	hypothetical protein	TssC
22	BTH_II1901	2307040..2307591 [-], 552	83717753	hypothetical protein	TssB
23	BTH_II1902	2307625..2308569 [-], 945	83717202	ImpA-like N-terminal family protein	TssA
24	BTH_II1903	2310190..2312109 [-], 1920	83716517	coenzyme A transferase
25	BTH_II1904	2312067..2312762 [+], 696	83717914	CDP-alcohol phosphatidyltransferase
26	BTH_II1905	2312759..2313532 [+], 774	83717482	2OG-Fe(II) oxygenase oxidoreductase

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

YPK_3563

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	BTH_II1899	2304861..2305388 [-], 528	83718015	hypothetical protein	YPK_3563

Download FASTA format files

Proteins        Genes

N/A

(1) Russell AB et al. (2012). A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe. 11(5):538-49. [PudMed:22607806]

(2) Schwarz S et al. (2010). Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog. 6(8):e1001068. [PudMed:20865170]

This literature contains experimental investigation

This literature contains bioinformatics investigation