I. Summary
SecReT6 ID114 insolico
StrainBurkholderia thailandensis E264
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BTH_II18802277721..2279148 [-], 142883716540rhamnosyltransferase I subunit B 
2BTH_II18812279278..2280177 [-], 90083716935rhamnosyltransferase 1 subunit A 
3BTH_II18822280750..2281121 [-], 37283717991hypothetical protein 
4BTH_II18832281342..2281767 [-], 42683718045hypothetical protein 
5BTH_II18842281790..2282149 [-], 36083717690hypothetical protein 
6BTH_II18852282208..2285702 [-], 349583716717ImcF-like family protein  TssM
7BTH_II18862285699..2287483 [-], 178583717203hypothetical protein  TssL
8BTH_II18872287509..2288870 [-], 136283716495hypothetical protein  TssK
9BTH_II18882288867..2289346 [-], 48083718208lipoprotein  TssJ
10BTH_II18892289466..2289855 [-], 39083717888hypothetical protein 
11BTH_II18902289895..2290611 [-], 71783716070hypothetical protein 
12BTH_II18912290614..2291684 [-], 107183716702pentapeptide repeat-containing protein 
13BTH_II18922291684..2293834 [-], 215183717521hypothetical protein 
14BTH_II18932293904..2296192 [-], 228983716389Rhs element Vgr protein  TssI
15BTH_II18942296361..2298652 [-], 229283717067Rhs element Vgr protein  TssI
16BTH_II18952298643..2301486 [-], 284483717751ATP-dependent Clp protease, ATP-binding subunit ClpB  TssH
17BTH_II18962301489..2302478 [-], 99083718279hypothetical protein  TssG
18BTH_II18972302475..2304337 [-], 186383716407hypothetical protein  TssF
19BTH_II18982304351..2304782 [-], 43283717049hypothetical protein  TssE
20BTH_II18992304861..2305388 [-], 52883718015hypothetical protein  TssD
21BTH_II19002305532..2307037 [-], 150683718249hypothetical protein  TssC
22BTH_II19012307040..2307591 [-], 55283717753hypothetical protein  TssB
23BTH_II19022307625..2308569 [-], 94583717202ImpA-like N-terminal family protein  TssA
24BTH_II19032310190..2312109 [-], 192083716517coenzyme A transferase 
25BTH_II19042312067..2312762 [+], 69683717914CDP-alcohol phosphatidyltransferase 
26BTH_II19052312759..2313532 [+], 774837174822OG-Fe(II) oxygenase oxidoreductase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BTH_II18992304861..2305388 [-], 52883718015hypothetical protein YPK_3563

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Proteins        Genes
(1) Russell AB et al. (2012). A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe. 11(5):538-49. [PudMed:22607806] experimental in_silico
(2) Schwarz S et al. (2010). Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog. 6(8):e1001068. [PudMed:20865170] experimental
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation