I. Summary

SecReT6 ID	122
Strain	Burkholderia xenovorans LB400
Replicon	chromosome I [Browse all T6SS(s) in this replicon]
Accession	NC_007951
Location	2604751..2633179
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	0	1	1	1	0	0
Component	TssG	TssJ	TssK	TssM
Number	0	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	Bxe_A2108 (catB)	2600273..2601430 [-], 1158	91783706	muconate cycloisomerase
2	Bxe_A2107 (catR)	2601535..2602422 [+], 888	91783707	LysR family transcriptional regulator
3	Bxe_A2106	2602446..2603399 [-], 954	91783708	LysR family transcriptional regulator
4	Bxe_A2105	2603471..2604754 [+], 1284	91783709	(poly)aromatic ring hydroxylating dioxygenase, alpha subunit (Rieske (2Fe-2S) region)
5	Bxe_A2104	2604751..2605251 [+], 501	91783710	aromatic-ring-hydroxylating dioxygenase, beta subunit
6	Bxe_A2103	2605278..2606594 [+], 1317	91783711	major facilitator superfamily metabolite/H(+) symporter
7	Bxe_A2102	2606806..2607183 [+], 378	91783712	hypothetical protein
8	Bxe_A2101	2607167..2607709 [+], 543	91783713	hypothetical protein
9	Bxe_A2100	2607706..2608830 [+], 1125	91783714	Asp-tRNA Asn/Glu-tRNAGln amidotransferase A subunit
10	Bxe_A2099	2608888..2609631 [+], 744	91783715	short-chain dehydrogenase/reductase, TsaC-like
11	Bxe_A2098	2609791..2610888 [-], 1098	91783716	cytoplasmic protein	TssA
12	Bxe_A2097	2611074..2611778 [-], 705	91783717	hypothetical protein
13	Bxe_A2096	2612313..2615063 [+], 2751	91783718	ClpA/B-type chaperone, ATPase subunit ClpB, heat shock protein	TssH
14	Bxe_A2095	2615103..2615651 [+], 549	91783719	cytoplasmic protein	TssB
15	Bxe_A2094	2615685..2617178 [+], 1494	91783720	cytoplasmic protein	TssC
16	Bxe_A2093	2617345..2617746 [+], 402	91783721	hypothetical protein
17	Bxe_A2092	2617743..2618234 [+], 492	91783722	hypothetical protein
18	Bxe_A2091	2618277..2618759 [+], 483	91783723	cytoplasmic protein	TssD
19	Bxe_A2090	2618874..2619374 [+], 501	91783724	outer membrane lipoprotein	TssJ
20	Bxe_A2089	2619387..2620733 [+], 1347	91783725	temperature-dependent protein secretion, ImpJ	TssK
21	Bxe_A2088	2620821..2622152 [+], 1332	91783726	hypothetical protein	TssL
22	Bxe_A2087	2622274..2623164 [-], 891	91783727	IS3 family transposase orfB
23	Bxe_A2086	2623161..2623448 [-], 288	91783728	transposase
24	Bxe_A2085	2623466..2627563 [+], 4098	91783729	membrane protein, SciS/IcmF-like	TssM
25	Bxe_A2084	2627759..2628160 [-], 402	91783730	cation resistance protein, CopC-like
26	Bxe_A2083	2628177..2629073 [-], 897	91783731	hypothetical protein
27	Bxe_A2082	2629182..2629652 [-], 471	91783732	hypothetical protein
28	Bxe_A2081	2629888..2631240 [+], 1353	91783733	TRAP-type uncharacterized transport system, periplasmic component protein
29	Bxe_A2080	2631257..2632111 [-], 855	91783734	ProQ activator of osmoprotectant transporter ProP
30	Bxe_A2079	2632268..2633179 [+], 912	91783735	LysR family transcriptional regulator
31	Bxe_A2078	2633216..2634592 [-], 1377	91783736	major facilitator superfamily metabolite/H(+) symporter
32	Bxe_A2077	2634716..2635534 [-], 819	91783737	enoyl-CoA hydratase/isomerase
33	Bxe_A2076	2635539..2637116 [-], 1578	91783738	long-chain-fatty acid CoA ligase
34	Bxe_A2075	2637109..2637639 [-], 531	91783739	oxidoreductase, iron-sulfur subunit

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

N/A

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

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