I. Summary
SecReT6 ID124 insolico
StrainCupriavidus metallidurans CH34
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1Rmet_0611665546..666292 [+], 74794309556TetR/AcrR family transcriptional regulator 
2Rmet_0612666464..667159 [+], 69694309557LuxR family two component transcriptional regulator 
3Rmet_0613667171..669108 [+], 193894309558putative two-component sensor histidine kinase 
4Rmet_0614668983..674208 [-], 522694309559hypothetical protein 
5Rmet_0615 (groS)674569..674859 [+], 29194309560co-chaperonin GroES 
6Rmet_0616 (groL)674944..676587 [+], 164494309561chaperonin GroEL 
7Rmet_0617676887..677321 [-], 43594309562hypothetical protein  TssE
8Rmet_0618 (clpB)677318..679999 [-], 268294309563Chaperone ClpB  TssH
9Rmet_0619680084..680569 [-], 48694309564hypothetical protein  TssD
10Rmet_0620680584..682302 [-], 171994309565putative OmpA/MotB  TagL
11Rmet_0621682313..682969 [-], 65794309566hypothetical protein  TssL
12Rmet_0622682966..683796 [-], 83194309567hypothetical protein  TssK
13Rmet_0623683645..684205 [-], 561335055499hypothetical protein  TssK
14Rmet_0624684362..685939 [-], 157894309569hypothetical protein  TssC
15Rmet_0625685965..686480 [-], 51694309570hypothetical protein  TssB
16Rmet_0626686770..689439 [+], 267094309571Rhs element Vgr protein  TssI
17Rmet_0627689436..691403 [+], 196894309572putative phospholipase D family protein 
18Rmet_0628691407..692714 [+], 130894309573putative sel1-like repeat; harboring protein 
19Rmet_0629692711..692911 [+], 20194309574putative phospholipase protein 
20Rmet_0630692915..694213 [+], 129994309575putative sel1-like repeat; harboring protein 
21Rmet_0631694310..694564 [+], 25594309576hypothetical protein  PAAR
22Rmet_0632694531..695808 [+], 127894309577hypothetical protein 
23Rmet_0633695874..699221 [+], 334894309578hypothetical protein  TssM
24Rmet_0634699369..700940 [+], 157294309579ImpA, N-terminal  TssA
25Rmet_0635700962..702782 [+], 182194309580hypothetical protein  TssF
26Rmet_0636702800..703888 [+], 108994309581hypothetical protein  TssG
27Rmet_0637703925..704494 [+], 57094309582hypothetical protein  TssJ
28Rmet_0638704628..705416 [-], 78994309583Metallophosphoesterase 
29Rmet_0639 (tadC)705624..706595 [-], 97294309584type II secretion system protein 
30Rmet_0640 (tadB)706647..707624 [-], 97894309585flp pilus assembly protein TadB 
31Rmet_0641 (cpaF1)707667..709037 [-], 137194309586flp pilus assembly ATPase CpaF 
32Rmet_0642 (cpaE1)709100..710293 [-], 119494309587flp pilus assembly ATPase 
33Rmet_0643710354..710812 [-], 45994309588flp pilus assembly protein 
34Rmet_0644710809..711339 [-], 53194309589flp pilus assembly protein 
35Rmet_0645711349..712653 [-], 130594309590hypothetical protein 
36Rmet_0646712676..713023 [-], 34894309591hypothetical protein 
37Rmet_0647 (cpaC1)713059..714921 [-], 186394309592Flp pilus assembly protein secretin CpaC 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1Rmet_0619680084..680569 [-], 48694309564hypothetical protein EC042_4529

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Proteins        Genes