I. Summary

SecReT6 ID	128
Strain	Yersinia pestis Nepal516
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_008149
Location	45430..61094
Comment
Function	N/A
T6SS Type	Type i; subtype i1
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	0	1	0	0	0	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	0	0	0	0

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	YPN_0025 (malG)	40963..41853 [-], 891	108810191	maltose transporter permease
2	YPN_0026 (malF)	41867..43444 [-], 1578	108810192	maltose transporter membrane protein
3	YPN_0027 (malE)	43631..44842 [-], 1212	108810193	maltose ABC transporter periplasmic protein
4	YPN_0028	45430..45666 [+], 237	108810194	hypothetical protein
5	YPN_0029	45670..46779 [+], 1110	108810195	maltose/maltodextrin transporter ATP-binding protein
6	YPN_0030 (lamB)	46850..48121 [+], 1272	108810196	maltoporin
7	YPN_0031	48362..49273 [+], 912	108810197	maltose regulon periplasmic protein
8	YPN_0032	49612..50022 [+], 411	108810198	hypothetical protein
9	YPN_0033	50174..50692 [-], 519	108810199	hypothetical protein	TssD
10	YPN_0034	51216..51713 [+], 498	108810200	hypothetical protein	TssB
11	YPN_0035	51781..53262 [+], 1482	108810201	hypothetical protein	TssC
12	YPN_0036	53269..53709 [+], 441	108810202	hypothetical protein	TssE
13	YPN_0037	53709..54935 [+], 1227	108810203	hypothetical protein	TssF
14	YPN_0038	54825..55610 [-], 786	108810204	transposase for insertion sequence IS1661
15	YPN_0039	55664..56308 [-], 645	108810205	insertion element IS1661 DNA-binding protein
16	YPN_0040	56921..59557 [-], 2637	108810206	phosphoenolpyruvate carboxylase
17	YPN_0041	59931..61094 [-], 1164	108810207	acetylornithine deacetylase
18	YPN_0042 (argC)	61345..62349 [+], 1005	108810208	N-acetyl-gamma-glutamyl-phosphate reductase
19	YPN_0043	62515..63291 [+], 777	108810209	acetylglutamate kinase
20	YPN_0044	63458..64831 [+], 1374	108810210	argininosuccinate lyase

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ECA2866

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	YPN_0033	50174..50692 [-], 519	108810199	hypothetical protein	ECA2866

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Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation