I. Summary
SecReT6 ID142 insolico
StrainEscherichia coli 536
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECP_27872932346..2932768 [+], 423110642945fucose operon FucU protein 
2ECP_27882932944..2933558 [+], 615110642946DNA-binding transcriptional activator 
3ECP_27892933602..2934702 [-], 1101110642947RNA 2'-O-ribose methyltransferase 
4ECP_27902934695..2935090 [-], 396110642948hypothetical protein 
5ECP_27912935109..2936026 [-], 918110642949DNA-binding transcriptional activator GcvA 
6ECP_27922936377..2936604 [-], 228110642950lipoprotein 
7ECP_27932936796..2938001 [+], 1206110642951cysteine sulfinate desulfinase 
8ECP_27942938001..2938444 [+], 444110642952hypothetical protein 
9ECP_27952938495..2939301 [-], 807110642953hypothetical protein 
10ECP_2796 (mltA)2939378..2940475 [-], 1098162138277murein transglycosylase A 
11ECP_28002941612..2942112 [+], 501110642955hypothetical protein  TssB
12ECP_28012942171..2943709 [+], 1539110642956hypothetical protein  TssC
13ECP_28022943727..2945064 [+], 1338110642957hypothetical protein  TssK
14ECP_28032945061..2945726 [+], 666110642958hypothetical protein  TssL
15ECP_28042945739..2947391 [+], 1653110642959OmpA family membrane protein  TagL
16ECP_28052947449..2947940 [+], 492110642960hemolysin-coregulated protein Hcp  TssD
17ECP_28062948132..2950768 [+], 2637110642961CLPA/B-type chaperone protein  TssH
18ECP_28072950780..2953269 [+], 2490110642962VGR-related protein  TssI
19ECP_28082953335..2954153 [+], 819110642963transmembrane protein 
20ECP_28092954167..2954760 [+], 594110642964hypothetical protein 
21ECP_28102954805..2957324 [+], 2520110642965VGR-related protein  TssI
22ECP_28112957317..2958105 [+], 789110642966hypothetical protein 
23ECP_28122958190..2959110 [+], 921110642967hypothetical protein 
24ECP_28132959367..2960581 [+], 1215110642968hypothetical protein 
25ECP_28142960533..2963964 [+], 3432110642969hypothetical protein  TssM
26ECP_28152963930..2965567 [+], 1638110642970hypothetical protein  TssA
27ECP_28162965573..2967003 [+], 1431110642971hypothetical protein  PAAR
28ECP_28172966996..2967400 [+], 405110642972hypothetical protein 
29ECP_28182967475..2967792 [+], 318110642973hypothetical protein  TssF
30ECP_28192967749..2969236 [+], 1488110642974hypothetical protein  TssF
31ECP_28202969200..2970279 [+], 1080110642975hypothetical protein  TssG
32ECP_28212970260..2970796 [+], 537110642976hypothetical protein  TssJ
33ECP_28222970800..2971228 [+], 429110642977hypothetical protein  TssE
34ECP_28232971228..2972604 [+], 1377110642978hypothetical protein  TssA
35ECP_28242972904..2973851 [-], 9481106429792-hydroxyacid dehydrogenase 
36ECP_28252973923..2974519 [-], 597110642980posphosugar isomerase 
37ECP_28262974522..2975697 [-], 1176110642981aminotransferase 
38ECP_28272975697..2977226 [-], 1530110642982PTS system, maltose and glucose-specific IIABC component 
39ECP_28282977309..2978133 [-], 825110642983transcriptional antiterminator protein 
40ECP_28292978391..2979644 [-], 1254110642984amidase 
41ECP_28302979876..2981207 [+], 1332110642985N-acetylglutamate synthase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECP_28052947449..2947940 [+], 492110642960hemolysin-coregulated protein Hcp EC042_4529

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Proteins        Genes
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation