I. Summary
SecReT6 ID143 insolico
StrainRalstonia eutropha H16
Repliconchromosome I [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1H16_A0635 (h16_A0635)675392..676096 [-], 705113866662uracil-DNA glycosylase 
2H16_A0636 (pinR)676035..676730 [-], 696113866663site-specific recombinase, DNA invertase Pin-like protein 
3H16_A0637 (h16_A0637)677019..677486 [+], 468113866664hypothetical protein 
4H16_A0638 (h16_A0638)677621..677950 [+], 330113866665ferredoxin 
5H16_A0639 (fdsR)677947..679041 [-], 1095113866666transcriptional regulator of formate dehydrogenase operon 
6H16_A0640 (fdsG)679192..679722 [+], 531113866667NAD-dependent formate dehydrogenase gamma subunit 
7H16_A0641 (fdsB)679719..681281 [+], 1563113866668NAD-dependent formate dehydrogenase beta subunit 
8H16_A0642 (fdsA)681317..684196 [+], 2880113866669NAD-dependent formate dehydrogenase alpha subunit 
9H16_A0643 (fdsC)684212..685078 [+], 867113866670formate dehydrogenase accessory protein 
10H16_A0644 (fdsD)685075..685299 [+], 225113866671NAD-dependent formate dehydrogenase delta subunit 
11H16_A0645 (h16_A0645)685318..686364 [-], 1047113866672hypothetical protein  TssA
12H16_A0646 (h16_A0646)686367..687407 [-], 1041113866673hypothetical protein  TssG
13H16_A0647 (h16_A0647)687410..689320 [-], 1911113866674hypothetical protein  TssF
14H16_A0648 (h16_A0648)689295..689816 [-], 522113866675hypothetical protein  TssE
15H16_A0649 (impE)689809..690645 [-], 837113866676ImpE family protein  TagJ
16H16_A0650 (h16_A0650)690635..691237 [-], 603113866677hypothetical protein 
17H16_A0651 (clpC1)691692..694406 [+], 2715113866678ATP-dependent protease Clp, ATPase subunit  TssH
18H16_A0652 (h16_A0652)694446..694979 [+], 534113866679hypothetical protein  TssB
19H16_A0653 (h16_A0653)695029..696522 [+], 1494113866680hypothetical protein  TssC
20H16_A0654 (h16_A0654)696651..697136 [+], 486113866681hemolysin-coregulated protein  TssD
21H16_A0655 (h16_A0655)697450..698544 [+], 1095113866682hypothetical protein 
22H16_A0656 (h16_A0656)698568..701162 [+], 2595113866683hypothetical protein  TssI
23H16_A0657 (h16_A0657)701196..703544 [+], 2349113866684hypothetical protein 
24H16_A0658 (h16_A0658)703636..705096 [+], 1461113866685hypothetical protein 
25H16_A0659 (h16_A0659)705214..706671 [+], 1458113866686hypothetical protein 
26H16_A0660 (h16_A0660)707107..707613 [+], 507113866687hypothetical protein  TssJ
27H16_A0661 (h16_A0661)707618..708961 [+], 1344113866688hypothetical protein  TssK
28H16_A0662 (h16_A0662)708958..710235 [+], 1278113866689hypothetical protein  TssL
29H16_A0663 (h16_A0663)710248..714069 [+], 3822113866690hypothetical protein  TssM
30H16_A0664 (h16_A0664)714048..715145 [+], 1098113866691hypothetical protein 
31H16_A0665 (h16_A0665)714828..715523 [-], 696113866692bifunctional transglycosylase and transpeptidase 
32H16_A0666 (ldh)715582..716631 [-], 1050113866693L-lactate dehydrogenase 
33H16_A0667 (h16_A0667)716645..718186 [-], 1542113866694Sodium:sulfate symporter transmembrane region 
34H16_A0668 (h16_A0668)718621..718866 [+], 246113866695hypothetical protein 
35H16_A0669 (h16_A0669)718917..719738 [+], 822113866696protein tyrosine/serine phosphatase 
36H16_A0670 (ackA2)719740..721203 [-], 1464113866697acetate kinase 
37H16_A0671 (h16_A0671)721496..723781 [+], 2286113866698hypothetical protein 
38H16_A0672 (h16_A0672)723866..724660 [+], 795113866699transcriptional repressor-molybdenum-binding protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1H16_A0654(h16_A0654)696651..697136 [+], 486113866681hemolysin-coregulated protein SciK

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Proteins        Genes
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation