I. Summary
SecReT6 ID144 insolico
StrainRalstonia eutropha H16
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i4a
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1H16_B24052714370..2714726 [-], 357116696341putative monooxygenase 
2H16_B2406 (cypX)2714754..2715878 [-], 1125116696342putative cytochrome P450 
3H16_B2407 (acrB10)2716034..2719210 [-], 3177116696343cation/multidrug efflux pump 
4H16_B2408 (acrA10)2719224..2720498 [-], 1275116696344cation/multidrug efflux system, mebrane-fusion component 
5H16_B2409 (acrC10)2720515..2721786 [-], 1272116696345cation/multidrug efflux system outer membrane porin 
6H16_B2410 (acrD)2721884..2722258 [-], 375116696346cation efflux system periplasmic protein 
7H16_B24112722544..2722888 [+], 345116696347hypothetical protein 
8H16_B24122722941..2723147 [-], 207116696348hypothetical protein 
9H16_B2413 (rpoE6)2723190..2723783 [-], 594116696349RNA polymerase sigma factor 
10H16_B24142723870..2725033 [-], 1164116696350hypothetical protein 
11H16_B24152725094..2726179 [-], 1086116696351hypothetical protein  TssA
12H16_B2416 (icmF)2726176..2730294 [-], 4119116696352IcmF-like protein  TssM
13H16_B24172730332..2731084 [-], 753116696353hypothetical protein  TssL
14H16_B24182731111..2732439 [-], 1329116696354hypothetical protein  TssK
15H16_B24192732485..2732988 [-], 504116696355hypothetical protein 
16H16_B2420 (gltP4)2733018..2734472 [-], 1455116696356proton/sodium-dicarboxylate symporter 
17H16_B2421 (racX)2734469..2735191 [-], 723116696357aspartate racemase 
18H16_B2422 (gltP3)2735203..2736537 [-], 1335116696358proton/sodium-dicarboxylate symporter 
19H16_B24232736534..2737283 [-], 750116696359periplasmic solute binding protein 
20H16_B24242737527..2737787 [-], 261116696360hypothetical protein 
21H16_B24252737805..2738191 [-], 387116696361hypothetical protein 
22H16_B24262738194..2738856 [-], 663116696362hypothetical protein 
23H16_B24272738915..2740816 [-], 1902116696363hypothetical protein  TssI
24H16_B2428 (clpB2)2740820..2743540 [-], 2721116696364ATP-dependent protease Clp, ATPase subunit  TssH
25H16_B24292743552..2744598 [-], 1047116696365quinoprotein dehydrogenase  TssG
26H16_B24302744553..2746328 [-], 1776116696366hypothetical protein  TssF
27H16_B24312746321..2746776 [-], 456116696367hypothetical protein  TssE
28H16_B24322746789..2747313 [-], 525116696368hypothetical protein  TssD
29H16_B24332747374..2748885 [-], 1512116696369hypothetical protein  TssC
30H16_B24342748949..2749485 [-], 537116696370hypothetical protein  TssB
31H16_B24352750276..2750995 [+], 720116696371response regulator 
32H16_B24362751281..2751637 [+], 357116696372hypothetical protein 
33H16_B24372751899..2752792 [+], 894116696373LysR family transcriptional regulator 
34H16_B24382752996..2754228 [+], 1233116696374acyl-CoA transferase/carnitine dehydratase 
35H16_B24392754334..2755311 [+], 978116696375extra-cytoplasmic solute receptor 
36H16_B2440 (hyuAB)2755733..2759461 [+], 3729116696376hydantoinase/oxoprolinase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation