I. Summary

SecReT6 ID	154
Strain	Burkholderia cenocepacia HI2424
Replicon	chromosome I [Browse all T6SS(s) in this replicon]
Accession	NC_008542
Location	499546..550557
Comment
Function	N/A
T6SS Type	Type i; subtype i4b
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	2	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

14

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	Bcen2424_0450	495319..495774 [+], 456	116688474	hypothetical protein
2	Bcen2424_0451	496114..496842 [-], 729	116688475	hypothetical protein
3	Bcen2424_0452	497082..497807 [+], 726	116688476	hypothetical protein
4	Bcen2424_0453	497867..498466 [+], 600	116688477	hypothetical protein
5	Bcen2424_0454	499546..501162 [+], 1617	116688478	phage protein
6	Bcen2424_0455	501276..502160 [+], 885	116688479	hypothetical protein
7	Bcen2424_0456	502224..503174 [+], 951	116688480	hypothetical protein
8	Bcen2424_0457	503892..504095 [+], 204	116688481	hypothetical protein
9	Bcen2424_0458	504205..505005 [-], 801	116688482	extracellular solute-binding protein
10	Bcen2424_0459	505362..508553 [+], 3192	116688483	Rhs element Vgr protein	TssI
11	Bcen2424_0460	508605..513260 [+], 4656	116688484	YD repeat-containing protein
12	Bcen2424_0461	513271..513846 [+], 576	116688485	hypothetical protein
13	Bcen2424_0462	514382..514699 [+], 318	116688486	hypothetical protein
14	Bcen2424_0463	514786..515568 [-], 783	116688487	hypothetical protein	TssL
15	Bcen2424_0464	515565..516911 [-], 1347	116688488	hypothetical protein	TssK
16	Bcen2424_0465	517014..517625 [-], 612	116688489	hypothetical protein	TssJ
17	Bcen2424_0466	517998..518633 [+], 636	116688490	TPR repeat-containing protein
18	Bcen2424_0467	518680..519195 [+], 516	116688491	hypothetical protein	TssB
19	Bcen2424_0468	519211..520701 [+], 1491	116688492	hypothetical protein	TssC
20	Bcen2424_0469	520772..521275 [+], 504	116688493	hypothetical protein	TssD
21	Bcen2424_0470	521338..521823 [+], 486	116688494	hypothetical protein	TssE
22	Bcen2424_0471	521900..523735 [+], 1836	116688495	hypothetical protein	TssF
23	Bcen2424_0472	523699..524799 [+], 1101	116688496	hypothetical protein	TssG
24	Bcen2424_0473	524841..527510 [+], 2670	116688497	ATPase	TssH
25	Bcen2424_0474	527554..528675 [+], 1122	116688498	ImpA domain-containing protein	TssA
26	Bcen2424_0475	528742..531303 [+], 2562	116688499	Rhs element Vgr protein	TssI
27	Bcen2424_0476	531303..532343 [+], 1041	116688500	hypothetical protein
28	Bcen2424_0477	532330..533166 [+], 837	116688501	hypothetical protein
29	Bcen2424_0478	533386..534321 [+], 936	116688502	hypothetical protein
30	Bcen2424_0479	534308..536569 [+], 2262	116688503	hypothetical protein
31	Bcen2424_0480	536652..536909 [-], 258	116688504	OmpA/MotB domain-containing protein	TagL
32	Bcen2424_0481	537086..537955 [+], 870	116688505	hypothetical protein
33	Bcen2424_0482	537988..538608 [+], 621	116688506	hypothetical protein
34	Bcen2424_0483	538876..539826 [-], 951	116688507	OmpA/MotB domain-containing protein	TagL
35	Bcen2424_0484	539831..540820 [-], 990	116688508	hypothetical protein
36	Bcen2424_0485	540817..544761 [-], 3945	116688509	ImcF domain-containing protein	TssM
37	Bcen2424_0486	545063..545908 [-], 846	116688510	peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins
38	Bcen2424_0487	546030..547034 [+], 1005	116688511	hypothetical protein
39	Bcen2424_0488	547247..548275 [+], 1029	116688512	Mg2+ transporter protein, CorA family protein
40	Bcen2424_0489	548319..548471 [-], 153	116688513	hypothetical protein
41	Bcen2424_0490	548496..549473 [-], 978	116688514	alcohol dehydrogenase
42	Bcen2424_0491	549637..550557 [+], 921	116688515	LysR family transcriptional regulator
43	Bcen2424_0492	550679..552847 [-], 2169	116688516	peptidase M1, membrane alanine aminopeptidase
44	Bcen2424_0493	552952..553209 [-], 258	116688517	hypothetical protein
45	Bcen2424_0494	553491..553985 [+], 495	116688518	hypothetical protein
46	Bcen2424_0495	554141..554473 [+], 333	116688519	hypothetical protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

BCAL0343

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	Bcen2424_0469	520772..521275 [+], 504	116688493	hypothetical protein	BCAL0343

Download FASTA format files

Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation