SecReT6
I. Summary
SecReT6 ID164 experimental
StrainAcidovorax citrulli AAC00-1
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_008752
Location1617808..1647773
CommentT6SS plays a role in BFB seed-to-seedling transmission, melon seed colonization and biofilm formation
Functionanti-eukaryotic
T6SS TypeType i; subtype i3
experimental Experimental investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111011111
ComponentTssGTssJTssKTssM
Number1111
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1AAVE_RS072651614190..1615446 [-], 1257500118598efflux RND transporter periplasmic adaptor subunit 
2AAVE_RS07270 (hpnC)1615609..1616532 [+], 9241174098326squalene synthase HpnC 
3AAVE_RS072751616619..1617287 [-], 669500118600hypothetical protein 
4AAVE_RS072801617808..1618290 [-], 483500118601type VI secretion system tube protein Hcp  TssD
5AAVE_RS072851618859..1620844 [+], 1986500118602serine/threonine protein kinase 
6AAVE_RS072901620951..1621451 [+], 501500118603TssQ family T6SS-associated lipoprotein 
7AAVE_RS07295 (tagH)1621473..1623806 [+], 2334500118604type VI secretion system-associated FHA domain protein TagH  Fha
8AAVE_RS073001623803..1624591 [+], 789754217893serine/threonine-protein phosphatase 
9AAVE_RS07305 (tssJ)1624635..1625198 [+], 564500118606type VI secretion system lipoprotein TssJ  TssJ
10AAVE_RS07310 (tssK)1625240..1626574 [+], 1335500118607type VI secretion system baseplate subunit TssK  TssK
11AAVE_RS073151626589..1627941 [+], 13531194615205DotU family type VI secretion system protein 
12AAVE_RS07320 (tssM)1627945..1631574 [+], 3630500118609type VI secretion system membrane subunit TssM  TssM
13AAVE_RS07325 (tagF)1631574..1632269 [+], 696889861065type VI secretion system-associated protein TagF 
14AAVE_RS07330 (tssA)1632316..1633356 [+], 1041500118611type VI secretion system protein TssA  TssA
15AAVE_RS07335 (tssB)1633519..1634067 [+], 549500118612type VI secretion system contractile sheath small subunit  TssB
16AAVE_RS07340 (tssC)1634081..1635580 [+], 1500500118613type VI secretion system contractile sheath large subunit  TssC
17AAVE_RS073451635702..1636490 [+], 789516008067virulence protein SciE type 
18AAVE_RS07350 (tssE)1636507..1637028 [+], 522500118615type VI secretion system baseplate subunit TssE  TssE
19AAVE_RS07355 (tssF)1637101..1638975 [+], 1875500118616type VI secretion system baseplate subunit TssF  TssF
20AAVE_RS07360 (tssG)1638972..1640138 [+], 1167500118617type VI secretion system baseplate subunit TssG  TssG
21AAVE_RS07365 (tssH)1640211..1642988 [+], 2778500118618type VI secretion system ATPase TssH  TssH
22AAVE_RS073751643375..1644013 [+], 639500118619hypothetical protein 
23AAVE_RS073801644043..1644546 [+], 504754218589M48 family metallopeptidase 
24AAVE_RS073851644568..1646817 [-], 2250500118621xanthine dehydrogenase family protein molybdopterin-binding subunit 
25AAVE_RS073901646823..1647773 [-], 951500118622xanthine dehydrogenase family protein subunit M 
26AAVE_RS07395 (paoA)1647777..1648395 [-], 619pseudogenealdehyde dehydrogenase iron-sulfur subunit 
27AAVE_RS07400 (murI)1648610..1649500 [-], 891500118623glutamate racemase 
28AAVE_RS074051649597..1651156 [-], 1560500118624fumarate hydratase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BTH_I0068

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

Download FASTA format files
Proteins        Genes
N/A
(1) Tian Y et al. (2014). The Type VI Protein Secretion System Contributes to Biofilm Formation and Seed-to-Seedling Transmission of Acidovorax citrulli on melon. Mol Plant Pathol. 16(1):38-47. [PudMed:24863458] experimental
(2) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation

Genomics & Bioinformatics Group in MML, SJTU