I. Summary
SecReT6 ID18 insolico
StrainYersinia pestis CO92
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YPO_RS057501064254..1064562 [-], 309pseudogenesite-specific integrase 
2YPO_RS057551064586..1065221 [-], 636488138797DUF2345 domain-containing protein 
3YPO_RS057601065829..1066526 [-], 6981194687962IS1 family transposase 
4YPO_RS057651066622..1067389 [-], 768488138800hypothetical protein 
5YPO_RS057701067376..1069673 [-], 2298488138801M23 family metallopeptidase 
6YPO_RS057751069689..1070324 [-], 636488138802DUF2345 domain-containing protein 
7YPO_RS057801070947..1071520 [-], 574pseudogeneIS1 family transposase 
8YPO_RS057851071549..1071743 [-], 195488144902hypothetical protein 
9YPO_RS057901071907..1072254 [-], 348514845521hypothetical protein 
10YPO_RS057951072398..1074620 [-], 2223488138803hydroxyethylthiazole kinase 
11YPO_RS058001074635..1076983 [-], 2349488138804type VI secretion system tip protein VgrG 
12YPO_RS05805 (tssH)1076980..1079628 [-], 2649488138805type VI secretion system ATPase TssH 
13YPO_RS058101080046..1080537 [-], 492488138806Hcp family type VI secretion system effector 
14YPO_RS058151080541..1082277 [-], 1737488156841OmpA family protein 
15YPO_RS058201082277..1082963 [-], 687488138807type VI secretion system protein TssL, short form 
16YPO_RS05825 (tssK)1082960..1084312 [-], 1353488140456type VI secretion system baseplate subunit TssK 
17YPO_RS05830 (tssC)1084324..1085868 [-], 1545488144688type VI secretion system contractile sheath large subunit 
18YPO_RS05835 (tssB)1085911..1086411 [-], 501488140454type VI secretion system contractile sheath small subunit 
19YPO_RS058401088261..1088619 [-], 359pseudogeneIS1 family transposase 
20YPO_RS058451088687..1089082 [-], 396488144692lipoprotein 
21YPO_RS058501089533..1090183 [-], 651488144694CPBP family intramembrane metalloprotease 
22YPO_RS058551091363..1092013 [+], 651488144695acyl-homoserine-lactone synthase 
23YPO_RS058601091994..1092737 [-], 744488140447LuxR family transcriptional regulator 
24YPO_RS058651093299..1094675 [+], 1377488140446peptidase 
25YPO_RS058701095052..1095885 [+], 834488140444intradiol ring-cleavage dioxygenase 
26YPO_RS058751096033..1096227 [-], 195488157453hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

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Proteins        Genes
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation