SecReT6
I. Summary
SecReT6 ID184 insolico
StrainBurkholderia pseudomallei 1106a
Repliconchromosome I [Browse all T6SS(s) in this replicon]
AccessionNC_009076
Location3541597..3571949
Comment
FunctionN/A
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111011111
ComponentTssGTssJTssKTssM
Number1111
12
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BURPS1106A_36383538655..3539053 [+], 399126453497hypothetical protein 
2BURPS1106A_36393539096..3539365 [+], 270126455446hypothetical protein 
3BURPS1106A_36403539468..3539698 [+], 231126452670hypothetical protein 
4BURPS1106A_36413539932..3540288 [-], 357126451515hypothetical protein 
5BURPS1106A_36423540314..3541582 [+], 1269126454853secretion protein 
6BURPS1106A_36433541597..3543858 [+], 2262126453800toxin secretion ABC transporter ATP-binding protein 
7BURPS1106A_36443543888..3545303 [+], 1416126452663TolC family type I secretion outer membrane protein 
8BURPS1106A_36453545288..3545437 [+], 150126453820hypothetical protein 
9BURPS1106A_36463545513..3546481 [-], 969126453523hypothetical protein 
10BURPS1106A_36473546493..3547458 [+], 966126452417D-alanyl-D-alanine carboxypeptidase 
11BURPS1106A_36483547487..3547624 [+], 138126453276hypothetical protein 
12BURPS1106A_36493547609..3547722 [+], 114126454205hypothetical protein 
13BURPS1106A_36503547730..3551623 [+], 3894126454823hypothetical protein  TssM
14BURPS1106A_36513551620..3552609 [+], 990126453923hypothetical protein 
15BURPS1106A_36523552614..3553546 [+], 933126453039ompA family protein  TagL
16BURPS1106A_36533553745..3554866 [-], 1122126452090ImpA-related N-terminal family protein  TssA
17BURPS1106A_36543554956..3557625 [-], 2670126451777ClpA/B type protease  TssH
18BURPS1106A_36553557659..3558759 [-], 1101126454687hypothetical protein  TssG
19BURPS1106A_36563558723..3560561 [-], 1839126453567hypothetical protein  TssF
20BURPS1106A_36573560641..3561123 [-], 483126452668hypothetical protein  TssE
21BURPS1106A_36583561181..3561684 [-], 504126451804hypothetical protein  TssD
22BURPS1106A_36593561757..3563247 [-], 1491126454940hypothetical protein  TssC
23BURPS1106A_36603563264..3563782 [-], 519126455085hypothetical protein  TssB
24BURPS1106A_36613563819..3564454 [-], 636126453290hypothetical protein 
25BURPS1106A_36623564616..3564753 [-], 138126452377hypothetical protein 
26BURPS1106A_36633564876..3565478 [+], 603126455022lipoprotein  TssJ
27BURPS1106A_36643565587..3566933 [+], 1347126453341hypothetical protein  TssK
28BURPS1106A_36653566930..3567715 [+], 786126452435hypothetical protein  TssL
29BURPS1106A_36663567817..3568182 [+], 366126453577phage tail completion protein 
30BURPS1106A_36673569271..3569687 [-], 417126451812DNA methylase 
31BURPS1106A_36683569772..3569969 [-], 198126452919bacteriophage tail protein I 
32BURPS1106A_36693570176..3570502 [-], 327126454262bacteriophage baseplate assembly protein J 
33BURPS1106A_36703570789..3571949 [-], 1161126455202ISBma1, transposase 
34BURPS1106A_36713572859..3573389 [+], 531126453279hypothetical protein  PAAR
35BURPS1106A_36723574186..3575289 [+], 1104126454388gp31 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BTH_I2697 , BCAL0343, BTH_I2698, BTH_I0068, BTH_I2693, BTH_I2705, BTH_II0310, BTH_II0090, BTH_I3226, BTH_I3225, BTH_I3225

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BURPS1106A_16101562992..1566327 [+], 3336126451485Rhs element Vgr protein BTH_I2697
2BURPS1106A_36583561181..3561684 [-], 504126451804hypothetical protein BCAL0343
3BURPS1106A_16091560574..1562883 [+], 2310126451896hypothetical protein BTH_I2698
4BURPS1106A_007975535..76503 [+], 969126452333hypothetical protein BTH_I0068
5BURPS1106A_16151568463..1571303 [+], 2841126453710Rhs element Vgr protein BTH_I2693
6BURPS1106A_16061555551..1558358 [+], 2808126454317Rhs element Vgr protein BTH_I2705
7BURPS1106A_A27572692398..2693303 [+], 906126455552hypothetical protein BTH_II0310
8BURPS1106A_A010191141..93381 [+], 2241126457559Type V secretory pathway, adhesin AidA BTH_II0090
9BURPS1106A_A16141580625..1582865 [-], 2241126457785hypothetical protein BTH_I3226
10BURPS1106A_A010088347..91127 [+], 2781126457812Rhs element Vgr protein BTH_I3225
11BURPS1106A_A16151582879..1585665 [-], 2787126458074putative Rhs element Vgr protein BTH_I3225

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Proteins        Genes

Homology Immunity protein list
BTH_I2700, BTH_I0069

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BURPS1106A_16081559379..1559888 [+], 510126452772hypothetical protein BTH_I2700
2BURPS1106A_008076490..76858 [+], 369126453223lipoprotein BTH_I0069

Download FASTA format files
Proteins        Genes
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
 
in_silico This literature contains bioinformatics investigation

Genomics & Bioinformatics Group in MML, SJTU