I. Summary

SecReT6 ID	185
Strain	Burkholderia pseudomallei 1106a
Replicon	chromosome II [Browse all T6SS(s) in this replicon]
Accession	NC_009078
Location	110188..151260
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	2	1	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	BURPS1106A_A0122	106790..107197 [+], 408	126456087	haemagluttinin family protein
2	BURPS1106A_A0123 (pqaA)	107264..108715 [-], 1452	126458397	PqaA protein
3	BURPS1106A_A0124	108787..109002 [+], 216	126457476	hypothetical protein
4	BURPS1106A_A0125 (yfaZ)	109013..109465 [-], 453	226830795	outer membrane protein
5	BURPS1106A_A0126	110188..110697 [+], 510	126457347	fimbrial protein
6	BURPS1106A_A0127	110762..111499 [+], 738	126456489	fimbrial assembly chaperone protein
7	BURPS1106A_A0128	111612..114356 [+], 2745	126457629	fimbrial usher protein
8	BURPS1106A_A0129	114349..114921 [+], 573	126458042	major fimbrial subunit protein
9	BURPS1106A_A0130	114953..115642 [+], 690	126455750	hypothetical protein	TssL
10	BURPS1106A_A0131	115693..117321 [+], 1629	126456220	OmpA family protein	TagL
11	BURPS1106A_A0132	117284..117397 [+], 114	126456929	hypothetical protein
12	BURPS1106A_A0133	117711..118250 [+], 540	126457308	hypothetical protein	TssB
13	BURPS1106A_A0134	118284..119783 [+], 1500	126457919	hypothetical protein	TssC
14	BURPS1106A_A0135	119787..119939 [+], 153	126455880	hypothetical protein
15	BURPS1106A_A0136 (sciM)	119983..120465 [+], 483	126456784	SciM protein	TssD
16	BURPS1106A_A0137 (sciN)	120593..121135 [+], 543	126456559	SciN protein	TssJ
17	BURPS1106A_A0138	121132..122490 [+], 1359	126456681	hypothetical protein	TssK
18	BURPS1106A_A0139	122487..123788 [+], 1302	126457603	hypothetical protein	TssL
19	BURPS1106A_A0140	123803..127711 [+], 3909	126457982	ImcF/SciS family protein	TssM
20	BURPS1106A_A0141	127742..127864 [+], 123	126456250	hypothetical protein
21	BURPS1106A_A0142	127901..128470 [+], 570	126456361	hypothetical protein
22	BURPS1106A_A0143	128568..131258 [+], 2691	126457271	Rhs element Vgr protein	TssI
23	BURPS1106A_A0144	131327..131602 [+], 276	126458070	PAAR motif-containing protein	PAAR
24	BURPS1106A_A0145	131615..135067 [+], 3453	126455803	YD repeat-/RHS repeat-containing protein
25	BURPS1106A_A0146	135974..136150 [+], 177	126456464	hypothetical protein
26	BURPS1106A_A0147	136351..137379 [-], 1029	126455537	hypothetical protein
27	BURPS1106A_A0148	137434..138504 [-], 1071	126456359	ImpA-related N-terminal family protein	TssA
28	BURPS1106A_A0149	138523..139572 [-], 1050	126458527	hypothetical protein	TssG
29	BURPS1106A_A0150	139569..141449 [-], 1881	126456197	hypothetical protein	TssF
30	BURPS1106A_A0151	141451..141969 [-], 519	126456785	hypothetical protein	TssE
31	BURPS1106A_A0152	141956..142762 [-], 807	126457335	ImpE/SciE family protein	TagJ
32	BURPS1106A_A0153	142794..143849 [-], 1056	126458215	hypothetical protein
33	BURPS1106A_A0154	143908..144036 [-], 129	126455511	hypothetical protein
34	BURPS1106A_A0155	144139..144261 [-], 123	126458525	hypothetical protein
35	BURPS1106A_A0156 (clpB)	144237..146924 [+], 2688	126457862	chaperone clpB	TssH
36	BURPS1106A_A0157	146998..147135 [-], 138	126457183	hypothetical protein
37	BURPS1106A_A0158	147187..147306 [+], 120	126456486	hypothetical protein
38	BURPS1106A_A0159	147315..150413 [-], 3099	126455824	response regulator/sensor histidine kinase
39	BURPS1106A_A0160	151144..151260 [-], 117	126457506	hypothetical protein
40	BURPS1106A_A0161	151961..152623 [-], 663	126457628	LuxR family DNA-binding response regulator
41	BURPS1106A_A0162	152735..152896 [-], 162	126456924	hypothetical protein
42	BURPS1106A_A0163	153172..155541 [-], 2370	126455641	fimbrial usher family protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

N/A

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

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