I. Summary

SecReT6 ID	187
Strain	Burkholderia pseudomallei 1106a
Replicon	chromosome II [Browse all T6SS(s) in this replicon]
Accession	NC_009078
Location	678103..715527
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	2	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	BURPS1106A_A0690 (ppd)	673436..674617 [-], 1182	126457573	3-phosphonopyruvate decarboxylase
2	BURPS1106A_A0691	674614..676302 [-], 1689	126457777	phosphoenolpyruvate phosphomutase
3	BURPS1106A_A0692	676299..677066 [-], 768	126456776	hypothetical protein
4	BURPS1106A_A0693	677105..678106 [-], 1002	126457710	hypothetical protein
5	BURPS1106A_A0694	678103..678873 [-], 771	126457917	2OG-Fe(II) oxygenase family oxidoreductase
6	BURPS1106A_A0695	678873..679562 [-], 690	126455666	CDP-alcohol phosphatidyltransferase family protein
7	BURPS1106A_A0696	679927..681441 [+], 1515	126457343	acetyl-CoA hydrolase/transferase family protein
8	BURPS1106A_A0697	681538..681666 [+], 129	126456039	hypothetical protein
9	BURPS1106A_A0698	682476..682601 [+], 126	126456713	hypothetical protein
10	BURPS1106A_A0699	683162..684100 [+], 939	126457639	ImpA-related N-terminal family protein	TssA
11	BURPS1106A_A0700	684134..684682 [+], 549	126457683	hypothetical protein	TssB
12	BURPS1106A_A0701	684685..686190 [+], 1506	126458605	hypothetical protein	TssC
13	BURPS1106A_A0702	686334..686861 [+], 528	126456659	hypothetical protein	TssD
14	BURPS1106A_A0703	686941..687372 [+], 432	126456040	hypothetical protein	TssE
15	BURPS1106A_A0704	687386..689248 [+], 1863	126455797	hypothetical protein	TssF
16	BURPS1106A_A0705	689245..690234 [+], 990	126458306	hypothetical protein	TssG
17	BURPS1106A_A0706	690237..693107 [+], 2871	126457113	putative ATP-dependent Clp protease, ATP-binding subunit ClpB	TssH
18	BURPS1106A_A0707	693098..695389 [+], 2292	126456440	Rhs element Vgr protein	TssI
19	BURPS1106A_A0708	695412..695543 [-], 132	126457609	hypothetical protein
20	BURPS1106A_A0709	695555..697843 [+], 2289	126456731	Rhs element Vgr protein	TssI
21	BURPS1106A_A0710	697847..700063 [+], 2217	126456216	hypothetical protein
22	BURPS1106A_A0711	700063..701133 [+], 1071	126458544	hypothetical protein
23	BURPS1106A_A0712	701136..701852 [+], 717	126457880	hypothetical protein
24	BURPS1106A_A0713	701895..702284 [+], 390	126457245	hypothetical protein
25	BURPS1106A_A0714	702290..702883 [+], 594	126456475	putative lipoprotein	TssJ
26	BURPS1106A_A0715	702880..704241 [+], 1362	126455771	hypothetical protein	TssK
27	BURPS1106A_A0716	704324..705982 [+], 1659	126457957	hypothetical protein	TssL
28	BURPS1106A_A0717	705979..709482 [+], 3504	126457252	hypothetical protein	TssM
29	BURPS1106A_A0718	709541..709900 [+], 360	126456546	hypothetical protein
30	BURPS1106A_A0719	709923..710348 [+], 426	126455763	hypothetical protein
31	BURPS1106A_A0720	710548..710670 [-], 123	126458342	hypothetical protein
32	BURPS1106A_A0721	710624..710944 [+], 321	126457620	hypothetical protein
33	BURPS1106A_A0722	710981..711121 [+], 141	126457697	hypothetical protein
34	BURPS1106A_A0723 (rhlA)	711495..712394 [+], 900	126456665	rhamnosyltransferase I subunit A
35	BURPS1106A_A0724	712436..712738 [-], 303	126458335	hypothetical protein
36	BURPS1106A_A0725 (rhlB)	712628..713947 [+], 1320	126457580	rhamnosyltransferase I subunit B
37	BURPS1106A_A0726	713944..715527 [+], 1584	126457285	EmrB/QacA family drug resistance transporter
38	BURPS1106A_A0727	715479..715595 [+], 117	126456435	hypothetical protein
39	BURPS1106A_A0728	715780..716775 [+], 996	126457630	rhamnosyltransferase
40	BURPS1106A_A0729	716901..717083 [+], 183	126456611	hypothetical protein
41	BURPS1106A_A0730	717080..718663 [+], 1584	126455696	NodT family efflux transporter outer membrane lipoprotein
42	BURPS1106A_A0731	718979..719167 [-], 189	126458102	hypothetical protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

YPK_3563

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	BURPS1106A_A0702	686334..686861 [+], 528	126456659	hypothetical protein	YPK_3563

Download FASTA format files

Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation