I. Summary

SecReT6 ID	19
Strain	Yersinia pestis CO92
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_003143
Location	1651381..1695174
Comment
Function	N/A
T6SS Type	Type i; subtype i2
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	2	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	YPO1453	1647014..1647334 [+], 321	218928596	hypothetical protein
2	YPO1454	1647664..1648122 [+], 459	218928597	(3R)-hydroxymyristoyl-ACP dehydratase
3	YPO1455	1648112..1649395 [+], 1284	218928598	beta-ketoacyl-ACP synthase
4	YPO1456	1649388..1650134 [+], 747	218928599	3-ketoacyl-ACP reductase
5	YPO1457	1650150..1651388 [+], 1239	218928600	hydroxymethylglutaryl-coenzyme A synthase
6	YPO1458	1651381..1652100 [+], 720	218928601	enoyl-CoA hydratase
7	YPO1459	1652093..1652854 [+], 762	218928602	polyketide biosynthesis enoyl-CoA hydratase
8	YPO1460	1652857..1653645 [+], 789	218928603	short chain dehydrogenase
9	YPO1461	1653684..1654172 [+], 489	218928604	hypothetical protein
10	YPO1462	1654210..1654458 [+], 249	218928605	acyl carrier protein
11	YPO1463	1654557..1655405 [+], 849	218928606	acyl transferase
12	YPO1464	1655562..1655729 [+], 168	218928607	hypothetical protein
13	YPO1465	1656394..1656894 [+], 501	218928608	hypothetical protein	TssB
14	YPO1466	1656937..1658487 [+], 1551	218928609	hypothetical protein	TssC
15	YPO1467	1658499..1659851 [+], 1353	218928610	hypothetical protein	TssK
16	YPO1468	1659848..1660534 [+], 687	218928611	hypothetical protein	TssL
17	YPO1469	1660534..1662270 [+], 1737	218928612	hypothetical protein	TagL
18	YPO1470	1662274..1662765 [+], 492	218928613	hypothetical protein	TssD
19	YPO1471	1663153..1665795 [+], 2643	218928614	ATPase subunit of ATP-dependent protease	TssH
20	YPO1472	1665798..1668146 [+], 2349	218928615	hypothetical protein	TssI
21	YPO1473	1668162..1670462 [+], 2301	218928616	hypothetical protein
22	YPO1474	1670459..1671232 [+], 774	218928617	hypothetical protein
23	YPO1475	1671386..1671646 [+], 261	218928618	hypothetical protein
24	YPO1476	1671662..1673845 [+], 2184	218928619	hypothetical protein
25	YPO1477	1674018..1674488 [+], 471	218928620	hypothetical protein
26	YPO1481	1676764..1677885 [+], 1122	218928621	hypothetical protein
27	YPO1482	1677882..1681304 [+], 3423	218928622	hypothetical protein	TssM
28	YPO1483	1681348..1682949 [+], 1602	218928623	hypothetical protein	TssA
29	YPO1484	1682940..1684025 [+], 1086	218928624	hypothetical protein	PAAR
30	YPO1484a	1684025..1684495 [+], 471	218928625	hypothetical protein
31	YPO1485	1684716..1686479 [+], 1764	218928626	hypothetical protein	TssF
32	YPO1486	1686443..1687528 [+], 1086	218928627	hypothetical protein	TssG
33	YPO1487	1687596..1688084 [+], 489	218928628	hypothetical protein	TssJ
34	YPO1488	1688084..1688536 [+], 453	218928629	hypothetical protein	TssE
35	YPO1489	1688561..1689928 [+], 1368	218928630	hypothetical protein	TssA
36	YPO1490	1690140..1690763 [-], 624	218928631	hypothetical protein
37	YPO1491 (ybiT)	1691446..1693041 [+], 1596	218928632	ABC transporter ATP-binding protein
38	YPO1492	1693269..1693922 [+], 654	218928633	hypothetical protein
39	YPO1493 (y1062)	1693966..1695174 [-], 1209	218928634	transposase
40	YPO1494 (moeB)	1695310..1696077 [-], 768	218928635	molybdopterin biosynthesis protein MoeB
41	YPO1495 (moeA)	1696082..1697356 [-], 1275	218928636	molybdopterin biosynthesis protein MoeA
42	YPO1496	1697891..1699201 [-], 1311	218928637	heme-binding protein
43	YPO1497	1699211..1699879 [-], 669	218928638	ABC transporter ATP-binding protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

EC042_4529

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	YPO1470	1662274..1662765 [+], 492	218928613	hypothetical protein	EC042_4529

Download FASTA format files

Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation