SecReT6
I. Summary
SecReT6 ID19 insolico
StrainYersinia pestis CO92
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_003143
Location1651381..1695174
Comment
FunctionN/A
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111121111
ComponentTssGTssJTssKTssM
Number1111
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YPO_RS082551647116..1647334 [+], 219488141828hypothetical protein 
2YPO_RS082601647598..1648122 [+], 525488141826beta-hydroxyacyl-ACP dehydratase 
3YPO_RS082651648112..1649395 [+], 1284488141824beta-ketoacyl-[acyl-carrier-protein] synthase family protein 
4YPO_RS082701649397..1650134 [+], 738488141822SDR family oxidoreductase 
5YPO_RS082751650150..1651388 [+], 1239488141820hydroxymethylglutaryl-CoA synthase family protein 
6YPO_RS082801651381..1652100 [+], 720488141818enoyl-CoA hydratase/isomerase family protein 
7YPO_RS082851652102..1652854 [+], 753488141817enoyl-CoA hydratase/isomerase family protein 
8YPO_RS082901652857..1653645 [+], 789488141816SDR family oxidoreductase 
9YPO_RS082951653732..1654172 [+], 441488157362lipocalin-like domain-containing protein 
10YPO_RS083001654210..1654458 [+], 249488141809acyl carrier protein 
11YPO_RS083051654557..1655405 [+], 849488141808ACP S-malonyltransferase 
12YPO_RS08310 (tssB)1656394..1656894 [+], 501488141806type VI secretion system contractile sheath small subunit 
13YPO_RS08315 (tssC)1656937..1658487 [+], 1551488143499type VI secretion system contractile sheath large subunit 
14YPO_RS08320 (tssK)1658499..1659851 [+], 1353488141803type VI secretion system baseplate subunit TssK 
15YPO_RS083251659848..1660534 [+], 687488138807type VI secretion system protein TssL, short form 
16YPO_RS083301660534..1662270 [+], 1737488143360OmpA family protein 
17YPO_RS083351662274..1662765 [+], 492488138806Hcp family type VI secretion system effector 
18YPO_RS08340 (tssH)1663153..1665795 [+], 2643488140719type VI secretion system ATPase TssH 
19YPO_RS083451665798..1668146 [+], 2349488140720type VI secretion system tip protein VgrG 
20YPO_RS083501668162..1670462 [+], 2301488140721M23 family metallopeptidase 
21YPO_RS083551670459..1671232 [+], 774488140722hypothetical protein 
22YPO_RS083601671386..1671646 [+], 261488140723DUF2345 domain-containing protein 
23YPO_RS083651671662..1673845 [+], 2184488140724M23 family metallopeptidase 
24YPO_RS083701674018..1674488 [+], 471488143356hypothetical protein 
25YPO_RS083751674953..1675823 [-], 871pseudogenetransposase 
26YPO_RS083801676653..1677885 [+], 1233488140727hypothetical protein 
27YPO_RS083851677882..1681304 [+], 3423488140728type VI secretion system membrane subunit 
28YPO_RS08390 (tssA)1681348..1682949 [+], 1602488140729type VI secretion system protein TssA 
29YPO_RS083951682967..1684025 [+], 1059488140730PAAR domain-containing protein 
30YPO_RS084001684040..1684495 [+], 456488140731hypothetical protein 
31YPO_RS08405 (tssF)1684716..1686479 [+], 1764488140732type VI secretion system baseplate subunit TssF 
32YPO_RS08410 (tssG)1686443..1687528 [+], 1086488140733type VI secretion system baseplate subunit TssG 
33YPO_RS08415 (tssJ)1687503..1688084 [+], 582488143344type VI secretion system lipoprotein TssJ 
34YPO_RS08420 (tssE)1688084..1688536 [+], 453488140735type VI secretion system baseplate subunit TssE 
35YPO_RS084251688561..1689928 [+], 1368488140736type VI secretion system ImpA family N-terminal domain-containing protein 
36YPO_RS084301690140..1690763 [-], 624488140737hypothetical protein 
37YPO_RS084351691446..1693041 [+], 1596488156788ABC-F family ATPase 
38YPO_RS084401693269..1693922 [+], 654488140739hypothetical protein 
39YPO_RS084451693966..1695174 [-], 1209488138535IS256 family transposase 
40YPO_RS08450 (moeB)1695310..1696080 [-], 771488140740molybdopterin-synthase adenylyltransferase MoeB 
41YPO_RS08455 (moeA)1696082..1697356 [-], 1275488140741molybdopterin molybdotransferase MoeA 
42YPO_RS08460 (darE)1697891..1699201 [-], 1311488140742darobactin maturation radical SAM/SPASM protein DarE 
43YPO_RS08465 (darD)1699211..1699879 [-], 669488140743darobactin export ABC transporter ATP-binding protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
EC042_4529

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

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Proteins        Genes
N/A
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
 
in_silico This literature contains bioinformatics investigation