I. Summary
SecReT6 ID20 insolico
StrainYersinia pestis CO92
Repliconchromosome [Browse all T6SS(s) in this replicon]
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YPO2710 (nadB)3037547..3039184 [-], 1638218929782L-aspartate oxidase 
2YPO2711 (rpoE)3039372..3039947 [+], 576218929783RNA polymerase sigma factor RpoE 
3YPO2712 (rseA)3039973..3040629 [+], 657218929784anti-RNA polymerase sigma factor SigE 
4YPO2713 (rseB)3040629..3041585 [+], 957218929785periplasmic negative regulator of sigmaE 
5YPO2714 (rseC)3041582..3042037 [+], 456218929786SoxR reducing system protein RseC 
6YPO2715 (lepA)3042058..3042912 [-], 855218929787hypothetical protein 
7YPO2716 (lepA)3043412..3045211 [+], 1800218929788GTP-binding protein LepA 
8YPO2717 (lepB)3045221..3046219 [+], 999218929789signal peptidase I 
9YPO2718 (rnc)3046571..3047251 [+], 681218929790ribonuclease III 
10YPO2719 (era)3047248..3048159 [+], 912218929791GTP-binding protein Era 
11YPO2720 (recO)3048169..3048894 [+], 726218929792DNA repair protein RecO 
12YPO2721 (y1093)3049021..3050043 [+], 1023218929793transposase for insertion sequence IS100 
13YPO27223050040..3050822 [+], 783218929794transposase/IS protein 
14YPO27233050889..3051674 [+], 786218929795OmpA family protein  TssL
15YPO27243051683..3055510 [+], 3828218929796hypothetical protein  TssM
16YPO27253055804..3058569 [+], 2766218929797hypothetical protein  TssI
17YPO27263058928..3059776 [+], 849218929798hypothetical protein 
18YPO27273059796..3060602 [+], 807218929799hypothetical protein  TagJ
19YPO27283060699..3061178 [+], 480218929800hypothetical protein  TssE
20YPO27293061203..3061550 [+], 348218929801hypothetical protein 
21YPO27303061607..3061948 [-], 342218929802hypothetical protein 
22YPO27313062324..3064363 [-], 2040218929803hypothetical protein 
23YPO2732 (lemA)3064368..3064910 [-], 543218929804hypothetical protein 
24YPO27333065526..3065993 [+], 468218929805hypothetical protein 
25YPO2734 (ccmA)3066438..3067094 [+], 657218929806cytochrome c biogenesis protein CcmA 
26YPO2735 (ccmB)3067064..3067723 [+], 660218929807heme exporter protein B 
27YPO2736 (ccmC)3067786..3068523 [+], 738218929808heme exporter protein C 
28YPO2737 (ccmD)3068520..3068822 [+], 303218929809heme exporter protein D 
29YPO2738 (ccmE)3068819..3069313 [+], 495218929810cytochrome c-type biogenesis protein CcmE 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation