I. Summary

SecReT6 ID	202
Strain	Yersinia pestis Pestoides F
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_009381
Location	1668932..1713584
Comment
Function	N/A
T6SS Type	Type i; subtype i2
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	2	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

14

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	YPDSF_1478	1665145..1666407 [+], 1263	145598762	hypothetical protein
2	YPDSF_1479	1666409..1667077 [+], 669	145598763	ABC transporter ATP-binding protein
3	YPDSF_1480	1667087..1668397 [+], 1311	145598764	heme-binding protein
4	YPDSF_1481	1668932..1670206 [+], 1275	145598765	molybdopterin biosynthesis protein MoeA
5	YPDSF_1482	1670208..1670978 [+], 771	145598766	molybdopterin biosynthesis protein MoeB
6	YPDSF_1483	1671043..1671696 [-], 654	145598767	hypothetical protein
7	YPDSF_1484	1671924..1673687 [-], 1764	145598768	ABC transporter ATP-binding protein
8	YPDSF_1485	1674202..1674825 [+], 624	145598769	hypothetical protein
9	YPDSF_1486	1675037..1676404 [-], 1368	145598770	hypothetical protein	TssA
10	YPDSF_1487	1676429..1676881 [-], 453	145598771	hypothetical protein	TssE
11	YPDSF_1488	1676881..1677462 [-], 582	145598772	hypothetical protein	TssJ
12	YPDSF_1489	1677437..1678522 [-], 1086	145598773	hypothetical protein	TssG
13	YPDSF_1490	1678486..1680249 [-], 1764	145598774	hypothetical protein	TssF
14	YPDSF_1491	1680470..1680940 [-], 471	145598775	hypothetical protein
15	YPDSF_1492	1680940..1681998 [-], 1059	145598776	hypothetical protein	PAAR
16	YPDSF_1493	1682016..1683617 [-], 1602	145598777	hypothetical protein	TssA
17	YPDSF_1494	1683661..1687083 [-], 3423	145598778	hypothetical protein	TssM
18	YPDSF_1495	1687080..1688312 [-], 1233	145598779	hypothetical protein
19	YPDSF_1496	1689142..1689315 [+], 174	145598780	IS630 orf
20	YPDSF_1497	1689424..1689744 [+], 321	145598781	transposase
21	YPDSF_1498	1689875..1690012 [+], 138	145598782	transposase
22	YPDSF_1499	1691120..1693303 [-], 2184	145598783	hypothetical protein
23	YPDSF_1500	1693319..1693579 [-], 261	145598784	hypothetical protein
24	YPDSF_1501	1693733..1694506 [-], 774	145598785	hypothetical protein
25	YPDSF_1502	1694503..1696734 [-], 2232	145598786	hypothetical protein
26	YPDSF_1503	1696819..1699167 [-], 2349	145598787	hypothetical protein	TssI
27	YPDSF_1504	1699170..1701812 [-], 2643	145598788	ATPase subunit of ATP-dependent protease	TssH
28	YPDSF_1505	1702200..1702691 [-], 492	145598789	hypothetical protein	TssD
29	YPDSF_1506	1702233..1702718 [+], 486	145598790	hypothetical protein
30	YPDSF_1507	1702695..1704431 [-], 1737	145598791	hypothetical protein	TagL
31	YPDSF_1508	1704431..1705117 [-], 687	145598792	membrane protein	TssL
32	YPDSF_1509	1705114..1706466 [-], 1353	145598793	hypothetical protein	TssK
33	YPDSF_1510	1706478..1708022 [-], 1545	145598794	hypothetical protein	TssC
34	YPDSF_1511	1708071..1708571 [-], 501	145598795	hypothetical protein	TssB
35	YPDSF_1512	1709560..1710408 [-], 849	145598796	acyl transferase
36	YPDSF_1513	1710793..1711281 [-], 489	145598797	hypothetical protein
37	YPDSF_1514	1711320..1712108 [-], 789	145598798	short chain dehydrogenase
38	YPDSF_1515	1712111..1712887 [-], 777	145598799	polyketide biosynthesis enoyl-CoA hydratase
39	YPDSF_1516	1712865..1713584 [-], 720	145598800	enoyl-CoA hydratase
40	YPDSF_1517	1713577..1714815 [-], 1239	145598801	putative hydroxymethylglutaryl-coenzyme A synthase
41	YPDSF_1518	1714831..1715577 [-], 747	145598802	beta-ketoacyl-(acyl-carrier-protein) reductase
42	YPDSF_1519	1715570..1716853 [-], 1284	145598803	beta-ketoacyl-(acyl-carrier-protein) synthase
43	YPDSF_1520	1716843..1717367 [-], 525	145598804	(3R)-hydroxymyristoyl-ACP dehydratase
44	YPDSF_1521	1717631..1717951 [-], 321	145598805	hypothetical protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

EC042_4529

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	YPDSF_1505	1702200..1702691 [-], 492	145598789	hypothetical protein	EC042_4529

Download FASTA format files

Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation