I. Summary
SecReT6 ID213 insolico
StrainKlebsiella pneumoniae subsp. pneumoniae MGH 78578
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1KPN_013181478632..1479546 [-], 915152969871LysR family transcriptional regulator 
2KPN_013191479689..1480423 [+], 7351529698727-alpha-hydroxysteroid dehydrogenase 
3KPN_013201480640..1482172 [+], 1533152969873metal-dependent phosphohydrolase 
4KPN_013211482371..1482919 [-], 549152969874putative intracellular protease/amidase 
5KPN_013221483578..1484069 [+], 492152969875hypothetical protein  TssB
6KPN_013231484106..1485656 [+], 1551152969876hypothetical protein  TssC
7KPN_013241485666..1487009 [+], 1344152969877hypothetical protein  TssK
8KPN_013251487006..1487695 [+], 690152969878hypothetical protein  TssL
9KPN_013261487692..1489398 [+], 1707152969879putative outer membrane protein  TagL
10KPN_013271489403..1489894 [+], 492152969880hypothetical protein  TssD
11KPN_013281490213..1492813 [+], 2601152969881putative protease  TssH
12KPN_013291492806..1495325 [+], 2520152969882hypothetical protein  TssI
13KPN_013301495318..1496529 [+], 1212152969883hypothetical protein 
14KPN_013311496534..1496938 [+], 405152969884hypothetical protein 
15KPN_013321496928..1497029 [+], 102152969885hypothetical protein 
16KPN_013331497333..1497584 [+], 252152969886hypothetical protein 
17KPN_013341497730..1499490 [+], 1761152969887putative membrane proteins 
18KPN_013351499487..1499747 [+], 261152969888hypothetical protein 
19KPN_013361499734..1500501 [+], 768152969889hypothetical protein 
20KPN_013371501395..1501784 [+], 390152969890putative transposase-related protein 
21KPN_013381502017..1502493 [+], 477152969891putative transposase-related protein 
22KPN_013391502858..1503199 [+], 342152969892maltose transport system permease 
23KPN_013401503379..1503513 [+], 135152969893hypothetical protein 
24KPN_013411503939..1505147 [+], 1209152969894putative structural protein 
25KPN_013421505225..1508599 [+], 3375152969895hypothetical protein  TssM
26KPN_013431508599..1510197 [+], 1599152969896hypothetical protein  TssA
27KPN_013441510228..1511283 [+], 1056152969897hypothetical protein  PAAR
28KPN_013451511280..1511750 [+], 471152969898hypothetical protein 
29KPN_013461511844..1512812 [-], 969152969899putative transposase, IS4 
30KPN_013471512893..1514647 [+], 1755152969900hypothetical protein  TssF
31KPN_013481516265..1516324 [-], 60152969901hypothetical protein 
32KPN_013491516455..1516838 [+], 384152969902hypothetical protein 
33KPN_013501516905..1517618 [-], 714152969903oxidoreductase 
34KPN_013511517692..1518285 [+], 594152969904putative regulatory protein TetR 
35KPN_01352 (yghA)1518290..1519045 [-], 756152969905oxidoreductase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1KPN_013271489403..1489894 [+], 492152969880hypothetical protein EC042_4529

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Proteins        Genes
(1) Sarris PF et al. (2011). Distribution of the putative type VI secretion system core genes in Klebsiella spp. Infect Genet Evol. 11(1):157-66. [PudMed:20932940] in_silico
in_silico This literature contains bioinformatics investigation