I. Summary
SecReT6 ID215 insolico
StrainKlebsiella pneumoniae subsp. pneumoniae MGH 78578
Repliconchromosome [Browse all T6SS(s) in this replicon]
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1KPN_03162 (ygdK)3471683..3472114 [+], 432152971684hypothetical protein 
2KPN_03163 (ygdL)3472157..3472978 [-], 822152971685putative enzyme 
3KPN_03164 (mltA)3473066..3474163 [-], 1098152971686murein transglycosylase A 
4KPN_031683476167..3477507 [+], 1341152971687hypothetical protein  TssK
5KPN_031693478172..3479875 [+], 1704152971688hypothetical protein  TagL
6KPN_031703480091..3482646 [+], 2556152971689hypothetical protein  TssI
7KPN_031713482649..3484100 [+], 1452152971690hypothetical protein 
8KPN_031723484185..3485213 [+], 1029152971691hypothetical protein 
9KPN_031733485322..3485693 [+], 372152971692hypothetical protein 
10KPN_031743485999..3487138 [+], 1140152971693hypothetical protein 
11KPN_031753487423..3490500 [+], 3078152971694hypothetical protein  TssM
12KPN_031763490493..3490885 [+], 393152971695hypothetical protein 
13KPN_031773491456..3492418 [+], 963152971696hypothetical protein 
14KPN_031783492511..3493107 [+], 597152971697hypothetical protein 
15KPN_031793493264..3495024 [+], 1761152971698hypothetical protein  TssF
16KPN_031803494988..3496070 [+], 1083152971699hypothetical protein  TssG
17KPN_031813496588..3497013 [+], 426152971700hypothetical protein  TssE
18KPN_03182 (cobT)3497239..3498294 [-], 1056152971701nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
19KPN_03183 (cobU)3498338..3498883 [-], 546152971702adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 
20KPN_03184 (cbiP)3498877..3500400 [-], 1524152971703cobyric acid synthase 
21KPN_03185 (cbiO)3500397..3501221 [-], 825152971704cobalt transporter ATP-binding subunit 
22KPN_03186 (cboQ)3501230..3501907 [-], 678152971705hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Sarris PF et al. (2011). Distribution of the putative type VI secretion system core genes in Klebsiella spp. Infect Genet Evol. 11(1):157-66. [PudMed:20932940] in_silico
in_silico This literature contains bioinformatics investigation