I. Summary
SecReT6 ID219 insolico
StrainPseudomonas aeruginosa PA7
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1PSPA7_35963723208..3723528 [+], 321152987163hypothetical protein 
2PSPA7_35973723584..3724141 [+], 558152988484hypothetical protein 
3PSPA7_3598 (folE)3724219..3724764 [+], 546152984341GTP cyclohydrolase I 
4PSPA7_35993724829..3725290 [-], 462152983688hypothetical protein 
5PSPA7_36003725536..3725916 [+], 381152987831hypothetical protein 
6PSPA7_3601 (stk1)3725944..3726933 [-], 990152984677serine-threonine kinase Stk1  Stk1
7PSPA7_3602 (stp1)3726930..3727658 [-], 729152985159serine/threonine phosphoprotein phosphatase Stp1  Stp1
8PSPA7_36033727658..3731185 [-], 3528152985576hypothetical protein  TssM
9PSPA7_36043731201..3732070 [-], 870152984393hypothetical protein  TssL
10PSPA7_36053732073..3733404 [-], 1332152986797hypothetical protein  TssK
11PSPA7_36063733401..3733907 [-], 507152989564putative lipoprotein  TssJ
12PSPA7_36073733913..3735115 [-], 1203152985292hypothetical protein  Fha
13PSPA7_36083735133..3735273 [-], 141152988569hypothetical protein 
14PSPA7_36093735362..3736873 [-], 1512152988906putative transcriptional regulator  Sfa2
15PSPA7_36103736884..3739511 [-], 2628152985112type VI secretion ATPase  TssH
16PSPA7_36113739524..3740531 [-], 1008152984934hypothetical protein  TssG
17PSPA7_36123740495..3742282 [-], 1788152988907hypothetical protein  TssF
18PSPA7_36133742501..3742908 [-], 408152985565hypothetical protein  TssE
19PSPA7_36143742921..3744396 [-], 1476152987994hypothetical protein  TssC
20PSPA7_36153744423..3744929 [-], 507152988603hypothetical protein  TssB
21PSPA7_36163744965..3746521 [-], 1557152985887hypothetical protein  TssA
22PSPA7_36173747445..3748047 [-], 603152984101putative glutathione S-transferase 
23PSPA7_36183748098..3749264 [-], 1167152983858putative aminotransferase 
24PSPA7_36193749346..3749819 [+], 474152984522MarR family transcriptional regulator 
25PSPA7_36203749842..3750483 [-], 642152983620hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PSPA7_12471259341..1259859 [+], 519152989635secreted protein Hcp PSPTO_5435

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Proteins        Genes
(1) Barret M et al. (2011). Genomic analysis of the type VI secretion systems in Pseudomonas spp.: novel clusters and putative effectors uncovered. Microbiology. 157(Pt 6):1726-39. [PudMed:21474537] in_silico
in_silico This literature contains bioinformatics investigation