I. Summary
SecReT6 ID22 insolico
StrainYersinia pestis CO92
Repliconchromosome [Browse all T6SS(s) in this replicon]
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YPO3581 (yhbG)3991676..3992401 [+], 726218930593ABC transporter ATP-binding protein YhbG 
2YPO3582 (rpoN)3992463..3993896 [+], 1434218930594RNA polymerase factor sigma-54 
3YPO3585 (ptsN)3994325..3994807 [+], 483218930595PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 
4YPO35863995113..3995967 [+], 855218930596hypothetical protein 
5YPO3587 (ptsO)3995964..3996236 [+], 273218930597phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 
6YPO3588 (pyrB)3996574..3997509 [+], 936218930598aspartate carbamoyltransferase 
7YPO3589 (pyrI)3997521..3997985 [+], 465218930599aspartate carbamoyltransferase 
8YPO35903998123..3998509 [+], 387218930600hypothetical protein 
9YPO3591 (y1093)3998850..3999872 [+], 1023218930601transposase for insertion sequence IS100 
10YPO35923999869..4000651 [+], 783218930602transposase/IS protein 
11YPO3592A4000721..4000924 [-], 204218930603insertion element IS1661 protein (gene fragment) 
12YPO35944001721..4002770 [+], 1050218930604hypothetical protein  TssG
13YPO35954002896..4004212 [+], 1317218930605hypothetical protein  Fha
14YPO35964004212..4004757 [+], 546218930606lipoprotein  TssJ
15YPO35974004760..4006106 [+], 1347218930607hypothetical protein  TssK
16YPO35984006106..4006873 [+], 768218930608hypothetical protein  TssL
17YPO3599 (clpB2)4006884..4009487 [+], 2604218930609Clp ATPase  TssH
18YPO36004009484..4010281 [+], 798218930610hypothetical protein 
19YPO36014010278..4010964 [+], 687218930611hypothetical protein 
20YPO36024010961..4012358 [+], 1398218930612hypothetical protein  TssA
21YPO36034012390..4015923 [+], 3534218930613hypothetical protein  TssM
22YPO36044016048..4016830 [+], 783218930614hypothetical protein  TssA
23YPO36054016827..4017360 [+], 534218930615hypothetical protein  TssA
24YPO36064017382..4019784 [+], 2403218930616Rhs accessory genetic element  TssI
25YPO36074019790..4020248 [+], 459218930617hypothetical protein 
26YPO36084020241..4023105 [+], 2865218930618hypothetical protein  PAAR
27YPO36094023133..4024503 [+], 1371218930619hypothetical protein 
28YPO36104024505..4024990 [+], 486218930620hypothetical protein 
29YPO36114025040..4025231 [-], 192218930621hypothetical protein 
30YPO36124025613..4026020 [-], 408218930622transcriptional regulator 
31YPO36134026381..4028579 [+], 2199218930623Rhs accessory genetic element  TssI
32YPO36144028582..4029004 [+], 423218930624hypothetical protein 
33YPO36154029049..4033587 [+], 4539218930625hypothetical protein  PAAR
34YPO36164033596..4034390 [+], 795218930626hypothetical protein 
35YPO36174034737..4035636 [-], 900218930627hypothetical protein 
36YPO36184035633..4036763 [-], 1131218930628oxidoreductase 
37YPO36194036958..4037899 [+], 942218930629AraC family transcriptional regulator 
38YPO36204038061..4038564 [-], 504218930630carbohydrate transport protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1YPO37084142000..4142518 [+], 519218930714hypothetical protein ECA2866

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Proteins        Genes
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation