I. Summary

SecReT6 ID	232
Strain	Escherichia coli E24377A
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_009801
Location	3128230..3143489
Comment
Function	N/A
T6SS Type	Type i; subtype i2
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	1	1	1	1	0
Component	TssG	TssJ	TssK	TssM
Number	0	1	1	0

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	EcE24377A_3116 (csdA)	3123414..3124619 [+], 1206	157156888	cysteine sulfinate desulfinase
2	EcE24377A_3117 (csdE)	3124619..3125062 [+], 444	157158642	cysteine desulfuration protein CsdE
3	EcE24377A_3118	3125113..3125919 [-], 807	157158275	ThiF family protein
4	EcE24377A_3119 (mltA)	3125996..3127093 [-], 1098	157155153	murein transglycosylase A
5	EcE24377A_3123	3128230..3128730 [+], 501	157154801	hypothetical protein	TssB
6	EcE24377A_3124	3128789..3130327 [+], 1539	157155143	hypothetical protein	TssC
7	EcE24377A_3125	3130345..3131682 [+], 1338	157155664	hypothetical protein	TssK
8	EcE24377A_3126	3131679..3132344 [+], 666	157156380	DotU family type IV/VI secretion system protein	TssL
9	EcE24377A_3127	3132357..3134009 [+], 1653	157156833	OmpA domain-containing protein	TagL
10	EcE24377A_3128	3134067..3134558 [+], 492	157157465	hypothetical protein	TssD
11	EcE24377A_3129	3134749..3137394 [+], 2646	157155408	ClpA/ClpB family protein	TssH
12	EcE24377A_3130	3137406..3139913 [+], 2508	157158477	ImpA family type VI secretion-associated protein	TssI
13	EcE24377A_3131	3139935..3140537 [+], 603	157158177	hypothetical protein
14	EcE24377A_3132	3140539..3141090 [+], 552	157157411	hypothetical protein
15	EcE24377A_3133	3141298..3141681 [+], 384	157159449	type VI secretion lipoprotein	TssJ
16	EcE24377A_3134	3141685..3142113 [+], 429	157158774	hypothetical protein	TssE
17	EcE24377A_3135	3142113..3143489 [+], 1377	157156697	ImpA-related N-terminal domain-containing protein	TssA
18	EcE24377A_3136	3143554..3144102 [+], 549	157158496	hypothetical protein
19	EcE24377A_3137 (amiC)	3144448..3145701 [-], 1254	157157803	N-acetylmuramoyl-L-alanine amidase
20	EcE24377A_3138 (argA)	3145933..3147264 [+], 1332	157156402	N-acetylglutamate synthase

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

EC042_4529

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	EcE24377A_3128	3134067..3134558 [+], 492	157157465	hypothetical protein	EC042_4529

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Proteins        Genes

N/A

N/A