I. Summary

SecReT6 ID	238
Strain	Salmonella enterica subsp. arizonae serovar 62:z4,z23:- str. RSK2980
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_010067
Location	2617346..2651626
Comment
Function	N/A
T6SS Type	Type i; subtype i2
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	2	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

14

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	SARI_02702	2614228..2614950 [+], 723	161504588	hypothetical protein
2	SARI_02703	2615112..2615519 [+], 408	161504589	hypothetical protein
3	SARI_02704	2615563..2615763 [-], 201	161504590	hypothetical protein
4	SARI_02705	2615945..2616184 [+], 240	161504591	hypothetical protein
5	SARI_02706	2616493..2617257 [+], 765	161504592	adhesin/invasin PagN
6	SARI_02707	2617493..2617657 [-], 165	161504593	hypothetical protein
7	SARI_02708	2617664..2618065 [+], 402	161504594	hypothetical protein
8	SARI_02709	2618086..2619468 [-], 1383	161504595	hypothetical protein	TssA
9	SARI_02710	2619515..2620759 [-], 1245	161504596	hypothetical protein
10	SARI_02711	2621574..2621828 [-], 255	161504597	hypothetical protein
11	SARI_02712	2621843..2622295 [-], 453	161504598	hypothetical protein	TssE
12	SARI_02713	2622288..2622830 [-], 543	161504599	hypothetical protein	TssJ
13	SARI_02714	2622805..2623908 [-], 1104	161504600	hypothetical protein	TssG
14	SARI_02715	2623863..2625626 [-], 1764	161504601	hypothetical protein	TssF
15	SARI_02716	2625648..2626178 [-], 531	161504602	hypothetical protein
16	SARI_02717	2626241..2626972 [-], 732	161504603	hypothetical protein
17	SARI_02718	2627003..2627488 [-], 486	161504604	hypothetical protein
18	SARI_02719	2627615..2628598 [-], 984	161504605	hypothetical protein	TssA
19	SARI_02720	2628598..2632005 [-], 3408	161504606	hypothetical protein	TssM
20	SARI_02721	2631992..2633149 [-], 1158	161504607	hypothetical protein
21	SARI_02722	2633449..2634303 [-], 855	161504608	hypothetical protein
22	SARI_02723	2634309..2636534 [-], 2226	161504609	hypothetical protein
23	SARI_02724	2636579..2639092 [-], 2514	161504610	hypothetical protein	TssI
24	SARI_02725	2639170..2639379 [-], 210	161504611	hypothetical protein
25	SARI_02726	2639397..2639861 [-], 465	161504612	hypothetical protein
26	SARI_02727	2639855..2640424 [-], 570	161504613	hypothetical protein
27	SARI_02728	2640439..2643033 [-], 2595	161504614	hypothetical protein	TssH
28	SARI_02729	2643250..2643756 [-], 507	161504615	hypothetical protein	TssD
29	SARI_02730	2643746..2645470 [-], 1725	161504616	hypothetical protein	TagL
30	SARI_02731	2645474..2646124 [-], 651	161504617	hypothetical protein	TssL
31	SARI_02732	2646121..2647458 [-], 1338	161504618	hypothetical protein	TssK
32	SARI_02733	2647477..2649024 [-], 1548	161504619	hypothetical protein	TssC
33	SARI_02734	2649059..2649595 [-], 537	161504620	hypothetical protein	TssB
34	SARI_02735	2650194..2650556 [-], 363	161504621	hypothetical protein
35	SARI_02736	2650632..2651483 [+], 852	161504622	hypothetical protein
36	SARI_02738	2651835..2652575 [-], 741	161504623	DNA polymerase III subunit epsilon
37	SARI_02739 (rnhA)	2652630..2653097 [+], 468	161504624	ribonuclease H
38	SARI_02740	2653094..2653816 [-], 723	161504625	hypothetical protein
39	SARI_02741	2653851..2654606 [+], 756	161504626	hydroxyacylglutathione hydrolase
40	SARI_02742 (mltD)	2654678..2656045 [+], 1368	161504627	membrane-bound lytic murein transglycosylase D

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

EC042_4529

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	SARI_02729	2643250..2643756 [-], 507	161504615	hypothetical protein	EC042_4529

Download FASTA format files

Proteins        Genes

N/A

(1) Blondel CJ et al. (2009). Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 10:354. [PudMed:19653904]

This literature contains bioinformatics investigation