SecReT6
I. Summary
SecReT6 ID257 insolico
StrainYersinia pseudotuberculosis YPIII
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_010465
Location906784..918536
Comment
FunctionN/A
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111101100
ComponentTssGTssJTssKTssM
Number0010
7
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YPK_0793903021..903671 [+], 651170023042abortive infection protein 
2YPK_0794904188..904517 [+], 330170023043lipoprotein 
3YPK_0795904585..904848 [+], 264170023044insertion element protein 
4YPK_0796905005..905376 [+], 372170023045hypothetical protein 
5YPK_0797905419..905574 [+], 156170023046hypothetical protein 
6YPK_0798906784..907284 [+], 501170023047type VI secretion protein  TssB
7YPK_0799907333..908877 [+], 1545170023048EvpB family type VI secretion protein  TssC
8YPK_0800908889..910241 [+], 1353170023049type VI secretion protein  TssK
9YPK_0801910238..910924 [+], 687170023050hypothetical protein  TssL
10YPK_0802910924..912660 [+], 1737170023051OmpA/MotB domain-containing protein  TagL
11YPK_0803912664..913155 [+], 492170023052Hcp1 family type VI secretion system effector  TssD
12YPK_0804913543..916185 [+], 2643170023053type VI secretion ATPase  TssH
13YPK_0805916188..918536 [+], 2349170023054ImpA family type VI secretion-associated protein  TssI
14YPK_0806918552..920849 [+], 2298170023055peptidase M23B 
15YPK_0807920836..921603 [+], 768170023056hypothetical protein 
16YPK_0808921699..921974 [+], 276170023057insertion element protein 
17YPK_0809922895..923407 [+], 513170023058hypothetical protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
EC042_4529

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1YPK_0803912664..913155 [+], 492170023052Hcp1 family type VI secretion system effector EC042_4529

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Proteins        Genes
N/A
(1) Zhang W et al. (2012). A type VI secretion system regulated by OmpR in Yersinia pseudotuberculosis functions to maintain intracellular pH homeostasis. Environ Microbiol. 15(2):557-69. [PudMed:23094603] experimental
(2) Zhang W et al. (2011). Modulation of a thermoregulated type VI secretion system by AHL-dependent quorum sensing in Yersinia pseudotuberculosis. Arch Microbiol. 193(5):351-63. [PudMed:21298257]
 
experimental This literature contains experimental investigation