I. Summary
SecReT6 ID259 insolico
StrainYersinia pseudotuberculosis YPIII
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YPK_25792833782..2834552 [+], 771170024804molybdopterin biosynthesis protein MoeB 
2YPK_25802834624..2835271 [-], 648170024805hypothetical protein 
3YPK_25812835489..2837084 [-], 1596170024806ABC transporter-like protein 
4YPK_25822837768..2838391 [+], 624170024807hypothetical protein 
5YPK_25832838599..2839966 [-], 1368170024808ImpA domain-containing protein  TssA
6YPK_25842839991..2840443 [-], 453170024809type VI secretion system lysozyme-like protein  TssE
7YPK_25852840443..2841024 [-], 582170024810hypothetical protein  TssJ
8YPK_25862840999..2842084 [-], 1086170024811type VI secretion protein  TssG
9YPK_25872842048..2843811 [-], 1764170024812type VI secretion protein  TssF
10YPK_25882844032..2844502 [-], 471170024813hypothetical protein 
11YPK_25892844502..2845560 [-], 1059170024814hypothetical protein  PAAR
12YPK_25902845578..2847179 [-], 1602170024815type VI secretion-associated protein  TssA
13YPK_25912847223..2850645 [-], 3423170024816ImcF domain-containing protein  TssM
14YPK_25922850642..2851874 [-], 1233170024817hypothetical protein 
15YPK_25932851981..2852763 [-], 783170024818hypothetical protein 
16YPK_25942852812..2853246 [-], 435170024819hypothetical protein 
17YPK_25952853585..2853857 [-], 273170024820hypothetical protein 
18YPK_25962853902..2854720 [-], 819170024821hypothetical protein 
19YPK_25972854732..2855034 [-], 303170024822hypothetical protein 
20YPK_25982855039..2855605 [-], 567170024823hypothetical protein  TssC
21YPK_25992855804..2855923 [-], 120170024824hypothetical protein 
22YPK_26002855972..2856472 [-], 501170024825type VI secretion protein  TssB
23YPK_26012857137..2857379 [-], 243170024826hypothetical protein 
24YPK_26022857435..2858283 [-], 849170024827putative acyltransferase 
25YPK_26032858382..2858630 [-], 249170024828putative acyl carrier protein 
26YPK_26042858678..2859010 [-], 333170024829hypothetical protein 
27YPK_26052859205..2859993 [-], 789170024830short-chain dehydrogenase/reductase SDR 
28YPK_26062859996..2860748 [-], 753170024831polyketide biosynthesis enoyl-CoA hydratase 
29YPK_26072860750..2861469 [-], 720170024832enoyl-CoA hydratase/isomerase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Zhang W et al. (2012). A type VI secretion system regulated by OmpR in Yersinia pseudotuberculosis functions to maintain intracellular pH homeostasis. Environ Microbiol. 15(2):557-69. [PudMed:23094603] experimental
(2) Zhang W et al. (2011). Modulation of a thermoregulated type VI secretion system by AHL-dependent quorum sensing in Yersinia pseudotuberculosis. Arch Microbiol. 193(5):351-63. [PudMed:21298257]
experimental This literature contains experimental investigation