I. Summary
SecReT6 ID259 insolico
StrainYersinia pseudotuberculosis YPIII
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YPK_RS12900 (moeB)2833782..2834552 [+], 771488140740molybdopterin-synthase adenylyltransferase MoeB 
2YPK_RS129052834624..2835271 [-], 648501261248hypothetical protein 
3YPK_RS129102835489..2837084 [-], 1596501261249ABC-F family ATPase 
4YPK_RS129152837768..2838391 [+], 624501261250hypothetical protein 
5YPK_RS129202838599..2839966 [-], 1368501261251type VI secretion system ImpA family N-terminal domain-containing protein 
6YPK_RS12925 (tssE)2839991..2840443 [-], 453499505453type VI secretion system baseplate subunit TssE 
7YPK_RS12930 (tssJ)2840443..2841024 [-], 582501261252type VI secretion system lipoprotein TssJ 
8YPK_RS12935 (tssG)2840999..2842084 [-], 1086501261253type VI secretion system baseplate subunit TssG 
9YPK_RS12940 (tssF)2842048..2843811 [-], 1764501261254type VI secretion system baseplate subunit TssF 
10YPK_RS129452844032..2844487 [-], 456488140731hypothetical protein 
11YPK_RS129502844502..2845560 [-], 1059501261255PAAR domain-containing protein 
12YPK_RS12955 (tssA)2845578..2847179 [-], 1602501261256type VI secretion system protein TssA 
13YPK_RS129602847223..2850645 [-], 3423501261257type VI secretion system membrane subunit 
14YPK_RS129652850642..2851874 [-], 1233501261258hypothetical protein 
15YPK_RS129702851981..2852799 [-], 819752489972hypothetical protein 
16YPK_RS129752852812..2853246 [-], 435501261260hypothetical protein 
17YPK_RS215152853585..2853857 [-], 273501261261hypothetical protein 
18YPK_RS129852853902..2854681 [-], 780752490075hypothetical protein 
19YPK_RS129902854732..2855034 [-], 303501261263hypothetical protein 
20YPK_RS12995 (tssC)2855039..2855929 [-], 891pseudogenetype VI secretion system contractile sheath large subunit 
21YPK_RS13000 (tssB)2855972..2856472 [-], 501488141806type VI secretion system contractile sheath small subunit 
22YPK_RS130102857435..2858283 [-], 849488141808ACP S-malonyltransferase 
23YPK_RS130152858382..2858630 [-], 249488141809acyl carrier protein 
24YPK_RS130202858678..2859118 [-], 441488157362lipocalin-like domain-containing protein 
25YPK_RS130252859205..2859993 [-], 789488141816SDR family oxidoreductase 
26YPK_RS130302859996..2860748 [-], 753488141817enoyl-CoA hydratase/isomerase family protein 
27YPK_RS130352860750..2861469 [-], 720488141818enoyl-CoA hydratase/isomerase family protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Zhang W et al. (2012). A type VI secretion system regulated by OmpR in Yersinia pseudotuberculosis functions to maintain intracellular pH homeostasis. Environ Microbiol. 15(2):557-69. [PudMed:23094603] experimental
(2) Zhang W et al. (2011). Modulation of a thermoregulated type VI secretion system by AHL-dependent quorum sensing in Yersinia pseudotuberculosis. Arch Microbiol. 193(5):351-63. [PudMed:21298257]
experimental This literature contains experimental investigation