I. Summary

SecReT6 ID	29
Strain	Yersinia pestis KIM10+
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_004088
Location	44888..60608
Comment
Function	N/A
T6SS Type	Type i; subtype i1
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	0	1	0	0	0	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	0	0	0	0

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	y0025 (psiE)	39981..40388 [+], 408	22123946	phosphate-starvation-inducible protein PsiE
2	y0026 (malG)	40531..41442 [-], 912	22123947	maltose ABC transporter permease
3	y0027 (malF)	41435..43027 [-], 1593	22123948	maltose transporter membrane protein
4	y0028 (malE)	43199..44410 [-], 1212	22123949	maltose ABC transporter substrate-binding protein
5	y0030	44888..45250 [+], 363	22123950	hypothetical protein
6	y0029	44998..45234 [+], 237	22123951	hypothetical protein
7	y0031 (malK)	45238..46347 [+], 1110	22123952	maltose ABC transporter ATP-binding protein
8	y0032 (lamB)	46418..47689 [+], 1272	161484925	maltoporin
9	y0033 (malM)	47912..48841 [+], 930	22123954	maltose regulon periplasmic protein
10	y0034	49078..49236 [-], 159	22123955	hypothetical protein
11	y0035	49240..49590 [+], 351	22123956	hypothetical protein
12	y0036	49742..50260 [-], 519	22123957	hypothetical protein	TssD
13	y0037	50781..51281 [+], 501	22123958	hypothetical protein	TssB
14	y0038	51349..52830 [+], 1482	22123959	hypothetical protein	TssC
15	y0039	52837..53277 [+], 441	22123960	hypothetical protein	TssE
16	y0040	53277..54503 [+], 1227	22123961	hypothetical protein	TssF
17	y0041	54393..54650 [-], 258	22123962	transposase
18	y0042	54689..55471 [-], 783	22123963	transposase/IS protein
19	y0043	55468..56490 [-], 1023	22123964	transposase
20	y0044	56560..56985 [+], 426	22123965	transposase
21	y0045	57193..57432 [-], 240	22123966	hypothetical protein
22	y0046 (glpF)	58060..58908 [+], 849	22123967	glycerol uptake facilitator protein
23	y0047 (glpK)	59085..60608 [+], 1524	22123968	glycerol kinase
24	y0048 (glpX)	60845..61855 [+], 1011	161484924	fructose 1,6-bisphosphatase II
25	y0049 (fpr)	62010..62756 [+], 747	22123970	ferredoxin-NADP reductase
26	y0050	63097..63597 [-], 501	22123971	hypothetical protein
27	y0051	63700..64314 [+], 615	22123972	hypothetical protein
28	y0052 (tpiA)	64443..65210 [+], 768	22123973	triosephosphate isomerase

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ECA2866

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	y0036	49742..50260 [-], 519	22123957	hypothetical protein	ECA2866

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Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation