I. Summary
SecReT6 ID295 insolico
StrainSalmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SeSA_A0290 (mltD)301930..303150 [-], 1221194734347membrane-bound lytic murein transglycosylase D 
2SeSA_A0291 (gloB)303369..304124 [-], 756194736047hydroxyacylglutathione hydrolase 
3SeSA_A0292304159..304881 [+], 723194735250methyltransferase 
4SeSA_A0293 (rnhA)304878..305345 [-], 468194736767ribonuclease H 
5SeSA_A0294 (dnaQ)305400..306140 [+], 741194736138DNA polymerase III subunit epsilon 
6SeSA_A0296306670..307713 [-], 1044194736484ImpA-related N- family protein  TssA
7SeSA_A0297307730..308725 [-], 996194736246type VI secretion protein, family protein  TssG
8SeSA_A0298 (vasA)308722..310605 [-], 1884194736842type VI secretion protein, family protein  TssF
9SeSA_A0299310621..311115 [-], 495194737470type VI secretion system lysozyme-related protein  TssE
10SeSA_A0300311112..311936 [-], 825194738070SciE protein  TagJ
11SeSA_A0301311923..312813 [-], 891194734411hypothetical protein 
12SeSA_A0302312896..313033 [-], 138194734926hypothetical protein 
13SeSA_A0303 (clpV)313193..315856 [+], 2664194734614type VI secretion ATPase, ClpV1 family protein  TssH
14SeSA_A0304315942..316232 [+], 291194735383hypothetical protein 
15SeSA_A0305316294..316836 [+], 543194734723type VI secretion protein, family protein  TssB
16SeSA_A0306316860..318368 [+], 1509194736373type VI secretion protein, EvpB/family protein  TssC
17SeSA_A0307318720..319001 [+], 282194735722cytoplasmic protein 
18SeSA_A0308319255..319740 [+], 486194734344hemolysin-coregulated protein  TssD
19SeSA_A0309320034..320519 [+], 486194735014cytoplasmic protein  STM0277 (e)
20SeSA_A0310320516..320887 [+], 372194734402periplasmic protein  STM0278 (i)
21SeSA_A0311321030..321515 [+], 486194734020hemolysin-coregulated protein  TssD
22SeSA_A0312321627..322118 [+], 492194736056type VI secretion lipoprotein, family protein  TssJ
23SeSA_A0313322122..323465 [+], 1344194735441type VI secretion protein, family protein  TssK
24SeSA_A0314323462..324766 [+], 1305194736479hypothetical protein  TssL
25SeSA_A0315324771..325544 [+], 774194737075hypothetical protein 
26SeSA_A0318 (icmF)326189..330058 [+], 3870194738351type VI secretion protein IcmF  TssM
27SeSA_A0319330058..330840 [+], 783194733908cytoplasmic protein 
28SeSA_A0320330837..331676 [+], 840194737231hypothetical protein 
29SeSA_A0321331666..331926 [+], 261194737681hypothetical protein 
30SeSA_A0322332051..334243 [+], 2193194735863Rhs-family protein  TssI
31SeSA_A0323334267..334713 [+], 447194735948hypothetical protein 
32SeSA_A0325338692..338826 [+], 135194737344hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SciK , SciK, Hcp, STM0277, STY2606

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SeSA_A0311321030..321515 [+], 486194734020hemolysin-coregulated protein SciK
2SeSA_A0308319255..319740 [+], 486194734344hemolysin-coregulated protein SciK
3SeSA_A33083190967..3191452 [-], 486194734856cytoplasmic protein Hcp
4SeSA_A0309320034..320519 [+], 486194735014cytoplasmic protein STM0277
5SeSA_A26042489772..2489990 [+], 219194735460hypothetical protein STY2606

Download FASTA format files
Proteins        Genes

Homology Immunity protein list
STM0278, STY2607

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SeSA_A0310320516..320887 [+], 372194734402periplasmic protein STM0278
2SeSA_A26052489990..2490508 [+], 519194734732periplasmic protein STY2607

Download FASTA format files
Proteins        Genes
(1) Blondel CJ et al. (2009). Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 10:354. [PudMed:19653904] in_silico
in_silico This literature contains bioinformatics investigation