I. Summary
SecReT6 ID298 insolico
StrainSalmonella enterica subsp. enterica serovar Agona str. SL483
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SeAg_B10871085511..1086170 [+], 660197250679hypothetical protein 
2SeAg_B10881086220..1086903 [-], 684197249426integrase, catalytic region 
3SeAg_B10891087074..1087475 [-], 402197248902ISPsy11, transposase OrfA 
4SeAg_B10901088338..1088709 [-], 372197251015hypothetical protein 
5SeAg_B10911089178..1089690 [-], 513197250460hypothetical protein 
6SeAg_B10921089731..1090177 [-], 447197250680hypothetical protein 
7SeAg_B10931090206..1090337 [-], 132197250164hypothetical protein 
8SeAg_B10941090415..1091650 [-], 1236197249126ImpA domain-containing protein  TssA
9SeAg_B10951091793..1092053 [-], 261197248637Pmt1  TssM
10SeAg_B10961092622..1093464 [-], 843197251081hypothetical protein 
11SeAg_B10971093488..1093967 [-], 480197251451type VI secretion system effector, Hcp1 family  TssD
12SeAg_B10981093986..1095347 [-], 1362197247752ImpA domain-containing protein  TssA
13SeAg_B1099 (icmF)1095358..1098819 [-], 3462197248094type VI secretion protein IcmF  TssM
14SeAg_B11001098898..1100310 [-], 1413197248442type VI secretion-associated protein, family  TssA
15SeAg_B11011100312..1101034 [-], 723197249226type VI secretion-associated protein, family 
16SeAg_B1102 (clpV)1101046..1103781 [-], 2736197248814type VI secretion ATPase, ClpV1 family  TssH
17SeAg_B11031103794..1104552 [-], 759197250605Aec26  TssL
18SeAg_B11041104557..1105888 [-], 1332197250367hypothetical protein  TssK
19SeAg_B11051105891..1106424 [-], 534197249936type VI secretion lipoprotein, VC_A0113 family  TssJ
20SeAg_B11061106421..1107707 [-], 1287197251439hypothetical protein  Fha
21SeAg_B11071107732..1108820 [-], 1089197250878type VI secretion protein, family  TssG
22SeAg_B1108 (vasA)1108784..1110637 [-], 1854197250629type VI secretion protein, family  TssF
23SeAg_B11091110642..1111058 [-], 417197250014type VI secretion system lysozyme-related protein  TssE
24SeAg_B11101111055..1112527 [-], 1473197251828type VI secretion protein, EvpB/family  TssC
25SeAg_B11111112818..1113321 [-], 504197251349type VI secretion protein, family  TssB
26SeAg_B11121113378..1113554 [+], 177197249291hypothetical protein 
27SeAg_B11131113950..1114468 [+], 519197247521hcp  TssD
28SeAg_B11141114691..1116832 [+], 2142197248170type VI secretion system Vgr family protein  TssI
29SeAg_B11151116901..1121067 [+], 4167197251192protein RhsA  PAAR
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
ECA4275 , Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SeAg_B11131113950..1114468 [+], 519197247521hcp ECA4275
2SeAg_B33023207255..3207740 [-], 486197249817cytoplasmic protein Hcp

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Proteins        Genes

Homology Immunity protein list

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SeAg_B25162448571..2449089 [+], 519197251724periplasmic protein STY2607

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Proteins        Genes
(1) Blondel CJ et al. (2009). Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 10:354. [PudMed:19653904] in_silico
in_silico This literature contains bioinformatics investigation