SecReT6
I. Summary
SecReT6 ID302 insolico
StrainSalmonella enterica subsp. enterica serovar Dublin str. CT_02021853
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_011205
Location1206170..1229487
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121121211
ComponentTssGTssJTssKTssM
Number1111
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SED_RS062001201427..1202533 [+], 1107446911330Gfo/Idh/MocA family oxidoreductase 
2SED_RS062051202700..1202993 [-], 294446036546hypothetical protein 
3SED_RS062101203024..1203242 [+], 219446803361hypothetical protein 
4SED_RS062201203843..1204301 [-], 459446546026DUF1311 domain-containing protein 
5SED_RS062251204425..1204796 [-], 372487407841hypothetical protein 
6SED_RS062301204805..1205245 [-], 441446944865hypothetical protein 
7SED_RS062351205265..1206137 [-], 873446170355LysM peptidoglycan-binding domain-containing protein 
8SED_RS062401206170..1206649 [-], 480447207707Hcp family type VI secretion system effector  TssD
9SED_RS062451206665..1208029 [-], 1365445998211type VI secretion system ImpA family N-terminal domain-containing protein  TssA
10SED_RS06250 (tssM)1208040..1211501 [-], 3462447059848type VI secretion system membrane subunit TssM  TssM
11SED_RS06255 (tssA)1211580..1212992 [-], 1413446287948type VI secretion system protein TssA  TssA
12SED_RS06260 (tagO)1212994..1213731 [-], 738446011293type VI secretion system-associated protein TagO 
13SED_RS06265 (tssH)1213728..1216463 [-], 2736446536953type VI secretion system ATPase TssH  TssH
14SED_RS062701216476..1217234 [-], 759446266123type IVB secretion system protein IcmH/DotU  TssL
15SED_RS06275 (tssK)1217239..1218570 [-], 1332446168600type VI secretion system baseplate subunit TssK  TssK
16SED_RS06280 (tssJ)1218573..1219076 [-], 5041524033542type VI secretion system lipoprotein TssJ 
17SED_RS06285 (tagH)1219103..1220389 [-], 1287446719629type VI secretion system-associated FHA domain protein TagH  Fha
18SED_RS06290 (tssG)1220414..1221502 [-], 1089446431194type VI secretion system baseplate subunit TssG  TssG
19SED_RS06295 (tssF)1221466..1223319 [-], 1854446316013type VI secretion system baseplate subunit TssF  TssF
20SED_RS06300 (tssE)1223324..1223740 [-], 417446534352type VI secretion system baseplate subunit TssE  TssE
21SED_RS06305 (tssC)1223737..1225209 [-], 1473445979144type VI secretion system contractile sheath large subunit  TssC
22SED_RS06315 (tssB)1225500..1226003 [-], 504445953397type VI secretion system contractile sheath small subunit  TssB
23SED_RS063251226633..1227151 [+], 519447065710Hcp family type VI secretion system effector  TssD
24SED_RS063301227373..1229487 [+], 2115446025603type VI secretion system tip protein VgrG  TssI
25SED_RS063351229589..1233806 [+], 4218445936774RHS repeat protein  PAAR
26SED_RS063401233806..1234138 [+], 333487407844hypothetical protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ECA4275 , Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

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Proteins        Genes
N/A
(1) Pezoa D et al. (2014). Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is involved in colonization of the avian and murine hosts. Vet Res. 45(1):2. [PudMed:24405577] experimental
(2) Blondel CJ et al. (2009). Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 10:354. [PudMed:19653904] in_silico
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation