I. Summary
SecReT6 ID302 insolico
StrainSalmonella enterica subsp. enterica serovar Dublin str. CT_02021853
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SeD_A12091201430..1202533 [+], 1104198245130oxidoreductase YjhC 
2SeD_A12101202700..1202978 [-], 279198242554GTP cyclohydrolase II 
3SeD_A12111203072..1203242 [+], 171198244180hypothetical protein 
4SeD_A12121203281..1203406 [+], 126198245479hypothetical protein 
5SeD_A12131204294..1204428 [-], 135198242349hypothetical protein 
6SeD_A12141204425..1204796 [-], 372198241857hypothetical protein 
7SeD_A12151205265..1206137 [-], 873198245586peptidoglycan-binding LysM 
8SeD_A12161206170..1206649 [-], 480198242614HNH endonuclease domain-containing protein  TssD
9SeD_A12171206665..1208029 [-], 1365198246064ImpA domain-containing protein  TssA
10SeD_A12181208040..1211501 [-], 3462198244477hypothetical protein  TssM
11SeD_A12191211580..1212992 [-], 1413198244825ImpA domain-containing protein  TssA
12SeD_A12201212994..1213731 [-], 738198243272type VI secretion-associated protein 
13SeD_A1221 (clpB)1213728..1216463 [-], 2736198243050chaperone protein clpB  TssH
14SeD_A12221216476..1217234 [-], 759198243709hypothetical protein  TssL
15SeD_A12231217239..1218570 [-], 1332198241763hypothetical protein  TssK
16SeD_A12241218573..1219106 [-], 534198242383type VI secretion lipoprotein family protein  TssJ
17SeD_A12251219103..1220389 [-], 1287198243153hypothetical protein  Fha
18SeD_A12261220414..1221502 [-], 1089198243822hypothetical protein  TssG
19SeD_A12271221466..1223319 [-], 1854198243146hypothetical protein  TssF
20SeD_A12281223324..1223740 [-], 417198243684hypothetical protein  TssE
21SeD_A12291223737..1225209 [-], 1473198241800hypothetical protein  TssC
22SeD_A12301225258..1225470 [-], 213198242376hypothetical protein  TssC
23SeD_A12311225500..1226003 [-], 504198245588type VI secretion protein  TssB
24SeD_A12321226060..1226239 [+], 180198246198hypothetical protein 
25SeD_A12331226633..1227151 [+], 519198242802hypothetical protein  TssD
26SeD_A12341227373..1229487 [+], 2115198242271Vgr family type VI secretion system  TssI
27SeD_A12351229589..1233806 [+], 4218198245895hypothetical protein  PAAR
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
ECA4275 , Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SeD_A12331226633..1227151 [+], 519198242802hypothetical protein ECA4275
2SeD_A34763338034..3338519 [-], 486198243473hypothetical protein Hcp

Download FASTA format files
Proteins        Genes
(1) Pezoa D et al. (2014). Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is involved in colonization of the avian and murine hosts. Vet Res. 45(1):2. [PudMed:24405577] experimental
(2) Blondel CJ et al. (2009). Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 10:354. [PudMed:19653904] in_silico
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation