I. Summary
SecReT6 ID304 insolico
StrainKlebsiella pneumoniae 342
Repliconchromosome [Browse all T6SS(s) in this replicon]
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1KPK_0930 (cbiQ)937701..938378 [+], 678206577163cobalt ABC transporter permease 
2KPK_0931 (cbiO)938387..939211 [+], 825206577904cobalt transporter ATP-binding subunit 
3KPK_0932 (cobQ)939208..940731 [+], 1524206575940cobyric acid synthase 
4KPK_0933 (cobU)940725..941270 [+], 546206576693adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 
5KPK_0934 (cobT)941314..942369 [+], 1056206580152nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
6KPK_0935942594..943019 [-], 426206580906type VI secretion system lysozyme-like protein  TssE
7KPK_0936943023..943556 [-], 534206579068type VI secretion lipoprotein  TssJ
8KPK_0937943537..944619 [-], 1083206579851type VI secretion protein  TssG
9KPK_0938 (vasA)944583..946343 [-], 1761206577037type VI secretion protein  TssF
10KPK_0939946468..949803 [-], 3336206576260ImcF domain-containing protein  TssM
11KPK_0940949803..950951 [-], 1149206575954hypothetical protein 
12KPK_0941951390..952496 [-], 1107206577602hypothetical protein 
13KPK_0942952586..953692 [-], 1107206577155hypothetical protein 
14KPK_0943953670..955460 [-], 1791206579443hypothetical protein 
15KPK_0944955480..957960 [-], 2481206578457ImpA family type VI secretion-associated protein  TssI
16KPK_0945958176..959879 [-], 1704206580585OmpA domain-containing protein  TagL
17KPK_0946959882..960547 [-], 666206580425type IV/VI secretion system protein, DotU family  TssL
18KPK_0947960544..961884 [-], 1341206577990hypothetical protein  TssK
19KPK_0948961886..962134 [-], 249206578337hypothetical protein 
20KPK_0949962625..962780 [-], 156206576408hypothetical protein 
21KPK_0953 (mltA)963889..964986 [+], 1098206579920murein transglycosylase A 
22KPK_0954965074..965883 [+], 810206580476ThiF family protein 
23KPK_0955 (csdE)966025..966462 [-], 438206578741cysteine desulfuration protein CsdE 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Sarris PF et al. (2011). Distribution of the putative type VI secretion system core genes in Klebsiella spp. Infect Genet Evol. 11(1):157-66. [PudMed:20932940] in_silico
in_silico This literature contains bioinformatics investigation