I. Summary
SecReT6 ID305 insolico
StrainKlebsiella pneumoniae 342
Repliconchromosome [Browse all T6SS(s) in this replicon]
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1KPK_20362099114..2100262 [+], 1149206577224galactonate dehydratase 
2KPK_20372100357..2101670 [+], 1314206579717major facilitator family transporter 
3KPK_20382101667..2102614 [+], 948206578811D-isomer specific 2-hydroxyacid dehydrogenase family protein 
4KPK_20392102672..2103001 [-], 330206580907hypothetical protein 
5KPK_20402103171..2103347 [+], 177206580664hypothetical protein 
6KPK_20412103631..2104971 [+], 1341206576125hypothetical protein  TssK
7KPK_20422104968..2105621 [+], 654206578427type IV/VI secretion system protein, DotU family  TssL
8KPK_20432105625..2107322 [+], 1698206577657OmpA domain-containing protein  TagL
9KPK_20452107440..2107601 [+], 162206577448hypothetical protein 
10KPK_20442107595..2107714 [-], 120206579150hypothetical protein 
11KPK_20462107781..2110408 [+], 2628206578686ImpA family type VI secretion-associated protein  TssI
12KPK_20472110411..2110929 [+], 519206579448LysM domain-containing protein 
13KPK_20482110992..2111915 [+], 924206576814IS903, transposase 
14KPK_20492112089..2113495 [+], 1407206576718transglycosylase 
15KPK_20502113716..2114351 [+], 636206575904hypothetical protein 
16KPK_20512114639..2115850 [+], 1212206580609hypothetical protein 
17KPK_20522116315..2119281 [+], 2967206579221ImcF-related family protein  TssM
18KPK_20532119415..2121178 [+], 1764206578488hypothetical protein  TssF
19KPK_20542121133..2122224 [+], 1092206578179type VI secretion protein  TssG
20KPK_20552122205..2122741 [+], 537206578921type VI secretion lipoprotein  TssJ
21KPK_20562122744..2123187 [+], 444206576798type VI secretion system lysozyme-like protein  TssE
22KPK_20572123207..2124592 [+], 1386206578041ImpA domain-containing protein  TssA
23KPK_20582124741..2125655 [+], 915206576480periplasmic sugar-binding protein 
24KPK_20592125739..2126068 [+], 330206577766hypothetical protein 
25KPK_2060 (engD)2126151..2127245 [-], 1095206581061GTP-dependent nucleic acid-binding protein EngD 
26KPK_2061 (pth)2127363..2127947 [-], 585206576264peptidyl-tRNA hydrolase 
27KPK_20622128220..2128495 [+], 276206578768hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Sarris PF et al. (2011). Distribution of the putative type VI secretion system core genes in Klebsiella spp. Infect Genet Evol. 11(1):157-66. [PudMed:20932940] in_silico
in_silico This literature contains bioinformatics investigation