I. Summary
SecReT6 ID306 insolico
StrainKlebsiella pneumoniae 342
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1KPK_30573109186..3111180 [-], 1995206580265lipoprotein 
2KPK_30583111249..3111779 [-], 531206578689lipoprotein 
3KPK_30593111847..3112377 [-], 531206575894lipoprotein 
4KPK_30603112445..3112972 [-], 528206576142lipoprotein 
5KPK_30613113036..3113815 [-], 780206578161hypothetical protein 
6KPK_30623113816..3116185 [-], 2370206577667ImpA family type VI secretion-associated protein  TssI
7KPK_3063 (clpV)3116187..3118841 [-], 2655206578966type VI secretion ATPase, ClpV1 family  TssH
8KPK_30643119106..3119597 [-], 492206577151type VI secretion system effector  TssD
9KPK_30653119602..3121305 [-], 1704206579667OmpA domain-containing protein  TagL
10KPK_30663121302..3121991 [-], 690206579269type IV/VI secretion system protein, DotU family  TssL
11KPK_30673121988..3123331 [-], 1344206580867hypothetical protein  TssK
12KPK_30683123341..3124885 [-], 1545206580274type VI secretion protein EvpB  TssC
13KPK_30693124928..3125419 [-], 492206577610hypothetical protein  TssB
14KPK_30703125473..3125601 [+], 129206576640hypothetical protein 
15KPK_30713126047..3126616 [+], 570206578791Pfpi family intracellular protease 
16KPK_30723126774..3127535 [-], 762206577855short chain dehydrogenase/reductase family oxidoreductase 
17KPK_30733127644..3128558 [+], 915206580488LysR family transcriptional regulator 
18KPK_30743128861..3129049 [+], 189206576638hypothetical protein 
19KPK_30753129103..3129573 [-], 471206579264anti-sigma B factor 
20KPK_30763129566..3129904 [-], 339206578466anti-anti-sigma factor 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1KPK_30643119106..3119597 [-], 492206577151type VI secretion system effector EC042_4529

Download FASTA format files
Proteins        Genes
(1) Sarris PF et al. (2011). Distribution of the putative type VI secretion system core genes in Klebsiella spp. Infect Genet Evol. 11(1):157-66. [PudMed:20932940] in_silico
in_silico This literature contains bioinformatics investigation