I. Summary

SecReT6 ID	309
Strain	Escherichia coli O157:H7 str. EC4115
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_011353
Location	243962..266987
Comment
Function	N/A
T6SS Type	Type i; subtype i1
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	2	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	0

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	ECH74115_0225 (rnhA)	239068..239535 [-], 468	209396174	ribonuclease H
2	ECH74115_0227 (dnaQ)	239600..240331 [+], 732	209400894	DNA polymerase III subunit epsilon
3	ECH74115_0229	240869..241669 [+], 801	209399184	hypothetical protein
4	ECH74115_0230	241854..242003 [-], 150	209398597	hypothetical protein
5	ECH74115_0233	243962..245371 [-], 1410	209395773	ImpA domain-containing protein	TssA
6	ECH74115_0235	248953..250365 [-], 1413	209399715	ImpA domain-containing protein	TssA
7	ECH74115_0236	250370..251113 [-], 744	209400989	type VI secretion-associated protein
8	ECH74115_0237 (clpV)	251110..253881 [-], 2772	209397886	type VI secretion ATPase, ClpV1 family	TssH
9	ECH74115_0238	253890..254651 [-], 762	209395897	hypothetical protein	TssL
10	ECH74115_0239	254656..255987 [-], 1332	209398751	hypothetical protein	TssK
11	ECH74115_0240	255990..256514 [-], 525	209399492	type VI secretion lipoprotein	TssJ
12	ECH74115_0241	256511..257791 [-], 1281	209400996	hypothetical protein	Fha
13	ECH74115_0242	257816..258898 [-], 1083	209398878	hypothetical protein	TssG
14	ECH74115_0243	258862..260712 [-], 1851	209396969	hypothetical protein	TssF
15	ECH74115_0244	260716..261129 [-], 414	209399977	hypothetical protein	TssE
16	ECH74115_0246	262662..262886 [-], 225	209395714	hypothetical protein	TssC
17	ECH74115_0247	262921..263421 [-], 501	209397057	hypothetical protein	TssB
18	ECH74115_0248	263848..263991 [+], 144	209397620	hypothetical protein
19	ECH74115_0249	264118..264636 [+], 519	209398721	hypothetical protein	TssD
20	ECH74115_0250	264669..264806 [+], 138	209399507	hypothetical protein
21	ECH74115_0251	264846..266987 [+], 2142	209399534	ImpA family type VI secretion-associated protein	TssI
22	ECH74115_0252	267063..271295 [+], 4233	209400273	RHS Repeat family protein	PAAR

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ECA4275

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	ECH74115_0249	264118..264636 [+], 519	209398721	hypothetical protein	ECA4275

Download FASTA format files

Proteins        Genes

N/A

N/A