I. Summary
SecReT6 ID309 insolico
StrainEscherichia coli O157:H7 str. EC4115
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECH74115_0225 (rnhA)239068..239535 [-], 468209396174ribonuclease H 
2ECH74115_0227 (dnaQ)239600..240331 [+], 732209400894DNA polymerase III subunit epsilon 
3ECH74115_0229240869..241669 [+], 801209399184hypothetical protein 
4ECH74115_0230241854..242003 [-], 150209398597hypothetical protein 
5ECH74115_0233243962..245371 [-], 1410209395773ImpA domain-containing protein  TssA
6ECH74115_0235248953..250365 [-], 1413209399715ImpA domain-containing protein  TssA
7ECH74115_0236250370..251113 [-], 744209400989type VI secretion-associated protein 
8ECH74115_0237 (clpV)251110..253881 [-], 2772209397886type VI secretion ATPase, ClpV1 family  TssH
9ECH74115_0238253890..254651 [-], 762209395897hypothetical protein  TssL
10ECH74115_0239254656..255987 [-], 1332209398751hypothetical protein  TssK
11ECH74115_0240255990..256514 [-], 525209399492type VI secretion lipoprotein  TssJ
12ECH74115_0241256511..257791 [-], 1281209400996hypothetical protein  Fha
13ECH74115_0242257816..258898 [-], 1083209398878hypothetical protein  TssG
14ECH74115_0243258862..260712 [-], 1851209396969hypothetical protein  TssF
15ECH74115_0244260716..261129 [-], 414209399977hypothetical protein  TssE
16ECH74115_0246262662..262886 [-], 225209395714hypothetical protein  TssC
17ECH74115_0247262921..263421 [-], 501209397057hypothetical protein  TssB
18ECH74115_0248263848..263991 [+], 144209397620hypothetical protein 
19ECH74115_0249264118..264636 [+], 519209398721hypothetical protein  TssD
20ECH74115_0250264669..264806 [+], 138209399507hypothetical protein 
21ECH74115_0251264846..266987 [+], 2142209399534ImpA family type VI secretion-associated protein  TssI
22ECH74115_0252267063..271295 [+], 4233209400273RHS Repeat family protein  PAAR
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECH74115_0249264118..264636 [+], 519209398721hypothetical protein ECA4275

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Proteins        Genes