I. Summary

SecReT6 ID	316
Strain	Escherichia coli S88
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_011742
Location	243428..266460
Comment
Function	N/A
T6SS Type	Type i; subtype i1
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	2	1	1	2	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	ECS88_0227 (gloB)	238994..239749 [-], 756	218557148	hydroxyacylglutathione hydrolase
2	ECS88_0228 (yafS)	239783..240505 [+], 723	218557149	S-adenosyl-L-methionine-dependent methyltransferase
3	ECS88_0229 (rnhA)	240502..240969 [-], 468	218557150	ribonuclease H
4	ECS88_0230 (dnaQ)	241034..241765 [+], 732	218557151	DNA polymerase III subunit epsilon
5	ECS88_0231 (yafT)	242303..243088 [+], 786	218557152	aminopeptidase
6	ECS88_0232	243428..243928 [-], 501	218557153	hypothetical protein	TssD
7	ECS88_0233	243925..245424 [-], 1500	218557154	hypothetical protein	TssA
8	ECS88_0234	245294..248821 [-], 3528	218557155	hypothetical protein	TssM
9	ECS88_0235	248841..250349 [-], 1509	218557156	hypothetical protein	TssA
10	ECS88_0236	250288..251031 [-], 744	218557157	hypothetical protein
11	ECS88_0237	251028..253787 [-], 2760	218557158	ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity	TssH
12	ECS88_0238	253797..254561 [-], 765	218557159	membrane protein Aec26	TssL
13	ECS88_0239	254566..255912 [-], 1347	218557160	hypothetical protein	TssK
14	ECS88_0240	255915..256439 [-], 525	218557161	hypothetical protein	TssJ
15	ECS88_0241	256436..257878 [-], 1443	218557162	hypothetical protein	Fha
16	ECS88_0242	257733..258782 [-], 1050	218557163	hypothetical protein	TssG
17	ECS88_0243	258746..260605 [-], 1860	218557164	hypothetical protein	TssF
18	ECS88_0244	260593..261018 [-], 426	218557165	hypothetical protein	TssE
19	ECS88_0245	261023..262507 [-], 1485	218557166	hypothetical protein	TssC
20	ECS88_0246	262530..263084 [-], 555	218557167	hypothetical protein	TssB
21	ECS88_0247	263739..264257 [+], 519	218557168	hypothetical protein	TssD
22	ECS88_0248	264478..266460 [+], 1983	218557169	hypothetical protein	TssI
23	ECS88_0249	266567..267613 [+], 1047	218557170	hypothetical protein
24	ECS88_0250	267606..269045 [+], 1440	218557171	hypothetical protein	PAAR
25	ECS88_0251	269020..269310 [+], 291	218557172	hypothetical protein
26	ECS88_0252	269568..269747 [+], 180	218557173	H-repeat associated protein
27	ECS88_0253	269847..270332 [+], 486	218557174	transposase
28	ECS88_0254	270561..271064 [+], 504	218557175	hypothetical protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ECA2866

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	ECS88_0247	263739..264257 [+], 519	218557168	hypothetical protein	ECA2866

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Proteins        Genes

N/A

N/A