I. Summary

SecReT6 ID	32
Strain	Yersinia pestis KIM10+
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_004088
Location	2952460..2996296
Comment
Function	N/A
T6SS Type	Type i; subtype i2
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	2	1	1	2	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	y2671	2947755..2948423 [+], 669	22126550	ABC transporter ATP-binding protein
2	y2672	2948433..2949743 [+], 1311	22126551	arylsulfatase
3	y2673 (moeA)	2950278..2951552 [+], 1275	22126552	molybdopterin biosynthesis protein MoeA
4	y2674 (moeB)	2951524..2952324 [+], 801	22126553	molybdopterin biosynthesis protein MoeB
5	y2675	2952460..2953668 [+], 1209	22126554	transposase
6	y2676	2953712..2954365 [-], 654	22126555	hypothetical protein
7	y2677	2954593..2956356 [-], 1764	22126556	ABC transporter ATP-binding protein
8	y2678	2956871..2957494 [+], 624	22126557	hypothetical protein
9	y2679	2957706..2959073 [-], 1368	22126558	hypothetical protein	TssA
10	y2680	2959098..2959367 [-], 270	22126559	hypothetical protein	TssE
11	y2681	2959360..2959551 [-], 192	22126560	hypothetical protein	TssE
12	y2682	2959551..2960132 [-], 582	22126561	hypothetical protein	TssJ
13	y2683	2960107..2961192 [-], 1086	22126562	hypothetical protein	TssG
14	y2684	2961156..2962919 [-], 1764	22126563	hypothetical protein	TssF
15	y2685	2963140..2963610 [-], 471	22126564	hypothetical protein
16	y2686	2963610..2964668 [-], 1059	22126565	hypothetical protein	PAAR
17	y2687	2964686..2966287 [-], 1602	22126566	hypothetical protein	TssA
18	y2688	2966331..2969753 [-], 3423	22126567	hypothetical protein	TssM
19	y2689	2969750..2970982 [-], 1233	22126568	hypothetical protein
20	y2690	2972094..2972414 [+], 321	22126569	transposase
21	y2691	2972545..2972682 [+], 138	22126570	transposase
22	y2692	2973147..2973617 [-], 471	22126571	hypothetical protein
23	y2694	2973790..2975952 [-], 2163	22126572	hypothetical protein
24	y2693	2973921..2974181 [-], 261	22126573	hypothetical protein
25	y2695	2975989..2976249 [-], 261	22126574	hypothetical protein
26	y2696	2976403..2977176 [-], 774	22126575	hypothetical protein
27	y2697	2977173..2979473 [-], 2301	22126576	hypothetical protein
28	y2698	2979489..2981837 [-], 2349	22126577	hypothetical protein	TssI
29	y2699 (clpB)	2981840..2984479 [-], 2640	22126578	heat shock protein	TssH
30	y2700	2984867..2985358 [-], 492	22126579	hypothetical protein	TssD
31	y2701	2984900..2985385 [+], 486	22126580	hypothetical protein
32	y2702	2985362..2987098 [-], 1737	22126581	hypothetical protein	TagL
33	y2703	2987098..2987784 [-], 687	22126582	hypothetical protein	TssL
34	y2704	2987781..2989133 [-], 1353	22126583	hypothetical protein	TssK
35	y2705	2989145..2990689 [-], 1545	22126584	hypothetical protein	TssC
36	y2706	2990732..2991235 [-], 504	22126585	hypothetical protein	TssB
37	y2707	2992221..2993069 [-], 849	22126586	acyl transferase
38	y2708	2993454..2993942 [-], 489	22126587	hypothetical protein
39	y2709	2993981..2994769 [-], 789	22126588	3-oxoacyl-ACP reductase
40	y2710	2994772..2995548 [-], 777	22126589	polyketide biosynthesis enoyl-CoA hydratase
41	y2711	2995526..2996296 [-], 771	22126590	enoyl-CoA hydratase
42	y2712 (pksG)	2996238..2997476 [-], 1239	22126591	hydroxymethylglutaryl-coenzyme A synthase
43	y2713 (fabG)	2997492..2998283 [-], 792	22126592	3-ketoacyl-ACP reductase
44	y2714 (fabF)	2998231..2999514 [-], 1284	22126593	3-ketoacyl-ACP synthase
45	y2715 (fabZ)	2999504..3000028 [-], 525	22126594	myristoyl-acyl carrier dehydratase
46	y2716	3000292..3000612 [-], 321	22126595	hypothetical protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

EC042_4529

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	y2700	2984867..2985358 [-], 492	22126579	hypothetical protein	EC042_4529

Download FASTA format files

Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation